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Sterling C. Johnson
University of Wisconsin-Madison
524Publications
60H-index
13.5kCitations
Publications 524
Newest
Published on May 9, 2018in Brain Imaging and Behavior 3.72
Amy Barzgari1
Estimated H-index: 1
(University of Wisconsin-Madison),
Jitka Sojkova3
Estimated H-index: 3
(University of Wisconsin-Madison)
+ 9 AuthorsChristopher R. Nicholas8
Estimated H-index: 8
(University of Wisconsin-Madison)
Parkinson’s disease (PD) is an age-related neurodegenerative disease that produces changes in movement, cognition, sleep, and autonomic function. Motor learning involves acquisition of new motor skills through practice, and is affected by PD. The purpose of the present study was to evaluate regional differences in resting cerebral blood flow (rCBF), measured using arterial spin labeling (ASL) MRI, during a finger-typing task of motor skill acquisition in PD patients compared to age- and gender-m...
1 Citations Source Cite
Published on May 18, 2019in Genetic Epidemiology 2.54
Burcu F. Darst5
Estimated H-index: 5
(University of Wisconsin-Madison),
Qiongshi Lu10
Estimated H-index: 10
(University of Wisconsin-Madison)
+ 1 AuthorsCorinne D. Engelman19
Estimated H-index: 19
Although Alzheimer9s disease (AD) is highly heritable, genetic variants known to be associated with AD only explain a small proportion of its heritability. Genetic factors may only convey disease risk in individuals with certain environmental exposures, suggesting that a multi-omics approach could reveal underlying mechanisms contributing to complex traits, such as AD. We developed an integrated network to investigate relationships between metabolomics, genomics, and AD risk factors using Wiscon...
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Published on May 7, 2019in Journal of Alzheimer's Disease 3.17
Lena L. Law1
Estimated H-index: 1
(University of Wisconsin-Madison),
Kate E. Sprecher4
Estimated H-index: 4
(University of Wisconsin-Madison)
+ 13 AuthorsSanjay Asthana46
Estimated H-index: 46
(University of Wisconsin-Madison)
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Published on Apr 17, 2019in Archives of Clinical Neuropsychology 1.59
Deborah Talamonti (Liverpool John Moores University), Rebecca L. Koscik25
Estimated H-index: 25
(University of Wisconsin-Madison)
+ 1 AuthorsDavide Bruno13
Estimated H-index: 13
(Liverpool John Moores University)
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Published on Apr 16, 2019in Neurology 8.05
Claire M. Erickson1
Estimated H-index: 1
,
Stephanie A. Schultz10
Estimated H-index: 10
+ 17 AuthorsBarbara B. Bendlin30
Estimated H-index: 30
Objective To examine whether the KLOTHO gene variant KL-VS attenuates APOE4- associated β-amyloid (Aβ) accumulation in a late-middle-aged cohort enriched with Alzheimer disease (AD) risk factors. Methods Three hundred nine late-middle-aged adults from the Wisconsin Registry for Alzheimer9s Prevention and the Wisconsin Alzheimer9s Disease Research Center were genotyped to determine KL-VS and APOE4 status and underwent CSF sampling (n = 238) and/or 11 C-Pittsburgh compound B (PiB)-PET imaging (n =...
1 Citations Source Cite
Published on Apr 2, 2019in Neurology 8.05
Anja Soldan11
Estimated H-index: 11
,
Corinne Pettigrew11
Estimated H-index: 11
+ 12 AuthorsSanjay Asthana46
Estimated H-index: 46
Objective To examine the long-term cognitive trajectories of individuals with normal cognition at baseline and distinct amyloid/tau/neurodegeneration (ATN) profiles. Methods Pooling data across 4 cohort studies, 814 cognitively normal participants (mean baseline age = 59.6 years) were classified into 8 ATN groups using baseline CSF levels of β-amyloid 1–42 as a measure of amyloid (A), phosphorylated tau 181 as a measure of tau (T), and total tau as a measure of neurodegeneration (N). Cognitive p...
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Published on Apr 1, 2019in Brain Imaging and Behavior 3.72
Patrick J. Lao7
Estimated H-index: 7
(University of Wisconsin-Madison),
Ben L. Handen3
Estimated H-index: 3
(University of Pittsburgh)
+ 8 AuthorsWilliam E. Klunk81
Estimated H-index: 81
(University of Pittsburgh)
The focus of Alzheimer’s disease (AD) neuroimaging research has shifted towards an investigation of the earliest stages of AD pathogenesis, which manifests in every young adult with Down syndrome (DS; trisomy 21) resulting from a deterministic genetic predisposition to amyloid precursor protein overproduction. Due to morphological differences in brain structure in the DS population, special consideration must be given to processing pipelines and the use of normative atlases developed for the non...
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Published on Mar 9, 2019in Brain Imaging and Behavior 3.72
Ryan J. Dougherty5
Estimated H-index: 5
(University of Wisconsin-Madison),
Elizabeth A. Boots9
Estimated H-index: 9
(University of Illinois at Chicago)
+ 13 AuthorsBarbara B. Bendlin30
Estimated H-index: 30
(University of Wisconsin-Madison)
Patterns of decreased resting cerebral blood flow (CBF) within the inferior temporal gyri, angular gyri, and posterior cingulate are a feature of aging and Alzheimer’s disease (AD) and have shown to be predictive of cognitive decline among older adults. Fitness and physical activity are both associated with many indices of brain health and may positively influence CBF, however, the majority of research to date has examined these measures in isolation, leaving the potential independent associatio...
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