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Vaughan J. Carr
University of New South Wales
PsychiatryPsychologyPsychosisClinical psychologySchizophrenia
357Publications
59H-index
15.2kCitations
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Publications 370
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#1Stacy Tzoumakis (Griffith University)H-Index: 9
#2Tyson Whitten (UNSW: University of New South Wales)H-Index: 1
Last. Melissa J. Green (UNSW: University of New South Wales)H-Index: 38
view all 8 authors...
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#1Kristin R. Laurens (UNSW: University of New South Wales)H-Index: 33
#2Fahkrul Islam (UNSW: University of New South Wales)
Last. Vaughan J. Carr (UNSW: University of New South Wales)H-Index: 59
view all 11 authors...
Abstract Background Maltreated children are at risk of poor educational outcomes, but also experience greater individual, family, and neighbourhood adversities that may obscure an understanding of relationships between child protection involvement and educational attainment. Objective To examine associations between child protection involvement and 3rd- and 5th-grade reading and numeracy attainment, while controlling multiple other adversities. Participants and Setting Participants were 56,860 A...
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#1Patrycja J. Piotrowska (NeuRA: Neuroscience Research Australia)
#2Tyson Whitten (UNSW: University of New South Wales)H-Index: 1
Last. Melissa J. Green (UNSW: University of New South Wales)H-Index: 38
view all 8 authors...
Adult psychosocial difficulties, including psychiatric disorders, are often preceded by childhood psychosocial vulnerabilities, presenting critical windows of opportunity for preventative intervention. The present study aimed to identify longitudinal patterns (representing transitions between profiles) of childhood socio-emotional and cognitive vulnerability in the general population from early to middle childhood, in relation to key risk factors (e.g. parental mental illness and offending). Dat...
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#1Mark Pinese (UNSW: University of New South Wales)H-Index: 23
#2Paul Lacaze (Monash University)H-Index: 5
Last. Dmitry Degrave (Garvan Institute of Medical Research)
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Population health research is increasingly focused on the genetic determinants of healthy ageing, but there is no public resource of whole genome sequences and phenotype data from healthy elderly individuals. Here we describe the first release of the Medical Genome Reference Bank (MGRB), comprising whole genome sequence and phenotype of 2570 elderly Australians depleted for cancer, cardiovascular disease, and dementia. We analyse the MGRB for single-nucleotide, indel and structural variation in ...
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#1William R. Reay (University of Newcastle)H-Index: 1
#2Joshua Atkins (University of Newcastle)H-Index: 3
Last. Murray J. Cairns (University of Newcastle)H-Index: 35
view all 5 authors...
Individuals with complex disorders typically have a heritable burden of common variation that can be expressed as a polygenic risk score (PRS). While PRS has some predictive utility, it lacks the molecular specificity to be directly informative for clinical interventions. We therefore sought to develop a framework to quantify an individual’s common variant enrichment in clinically actionable systems responsive to existing drugs. This was achieved with a metric designated the pharmagenic enrichme...
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#1Tyson Whitten (UNSW: University of New South Wales)H-Index: 1
#2Melissa J. Green (UNSW: University of New South Wales)H-Index: 38
Last. Kimberlie Dean (UNSW: University of New South Wales)H-Index: 25
view all 7 authors...
Contact with the police, as the first contact with the criminal justice system for young people and children, may signify individuals who are vulnerable to later adverse social and health outcomes....
1 CitationsSource
#1Amanda L. Neil (UTAS: University of Tasmania)H-Index: 14
#2Fakhrul Islam (UNSW: University of New South Wales)H-Index: 40
Last. Melissa J. Green (UNSW: University of New South Wales)H-Index: 38
view all 8 authors...
Abstract Background Longitudinal data on health costs associated with physical and mental conditions are not available for children reported to child protection services. Objective To estimate the costs of hospitalization for physical and mental health conditions by child protection status, including out-of-home-care (OOHC) placement, from birth until 13-years, and to assess the excess costs associated with child protection contact over this period. Participants and setting Australian population...
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#1Melissa J. Green (UNSW: University of New South Wales)H-Index: 38
#2Gabrielle Hindmarsh (UNSW: University of New South Wales)H-Index: 1
Last. Vaughan J. Carr (UNSW: University of New South Wales)H-Index: 59
view all 9 authors...
Objectives: To examine associations between being the subject of child protection reports in early childhood and diagnoses of mental disorders during middle childhood, by level of service response. Design, setting, participants: Retrospective analysis of linked New South Wales administrative data, 2001–2016, for a population cohort of children (mean age in 2016, 13.2 years; SD, 0.37 years) enrolled in the longitudinal NSW Child Development Study (NSW-CDS), wave 2 linkage. Main outcome measures: ...
1 CitationsSource
#1Phil H. LeeH-Index: 39
#2Verneri AnttilaH-Index: 31
Last. Jordan W. SmollerH-Index: 78
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Summary Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette syndrome. ...
8 CitationsSource
#1Xiaoman LiuH-Index: 2
#2Siew-Kee LowH-Index: 15
Last. Murray J. CairnsH-Index: 35
view all 20 authors...
Supplemental material, Supplementary_files_of_GWAS_of_schizophrenia_684indiv_EUR_3covariates_v3-revised_v1 for Wnt receptor gene FZD1 was associated with schizophrenia in genome-wide SNP analysis of the Australian Schizophrenia Research Bank cohort by Xiaoman Liu, Siew-Kee Low, Joshua R Atkins, Jing Qin Wu, William R Reay, Heath M Cairns, Melissa J Green, Ulrich Schall, Assen Jablensky, Bryan Mowry, Patricia T Michie, Stan V Catts, Frans Henskens, Christos Pantelis, Carmel Loughland, Alan V Bodd...
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