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Shiyu Tao
Nanjing Agricultural University
21Publications
6H-index
117Citations
Publications 21
Newest
#1Liuping Cai (NAU: Nanjing Agricultural University)H-Index: 2
#2Canfeng Hua (NAU: Nanjing Agricultural University)H-Index: 4
Last.Ruqian Zhao (NAU: Nanjing Agricultural University)H-Index: 22
view all 8 authors...
Abstract Chronic stress has a profound effect on health in both animals and humans. Dexamethasone (Dex), a synthetic glucocorticoid, is used to induce chronic stress in many studies. The impact of chronic stress on epithelial cells of hindgut of ruminants is still unknown. In this study, we investigated the effect of chronic stress induced by long term injection of low dosage of Dex on the colonic epithelium of goats. The results showed that Dex exposure increased the number of TUNEL-positive ce...
Source
#1Shiyu Tao (NAU: Nanjing Agricultural University)H-Index: 6
#2Qinwei Sun (NAU: Nanjing Agricultural University)H-Index: 9
Last.Ruqian Zhao (NAU: Nanjing Agricultural University)H-Index: 22
view all 7 authors...
4 CitationsSource
#1Canfeng Hua (NAU: Nanjing Agricultural University)H-Index: 4
#2Yali Geng (NAU: Nanjing Agricultural University)H-Index: 4
Last.Ruqian Zhao (NAU: Nanjing Agricultural University)H-Index: 22
view all 8 authors...
Dexamethasone (Dex), an artificially synthetic cortisol substitute, is commonly used as an anti-inflammatory drug, and is also employed to mimic the stress state experimentally. It is well known that chronic stress disturbs the gut microbiota community and digestive functions. However, no relevant studies have been conducted in ruminants. In this study, a low dosage of Dex (0.2 mg/kg body weight, Dex group, n = 5) was consecutively injected intramuscularly for 21 days to simulate chronic stress ...
1 CitationsSource
#1Liqiong Niu (NAU: Nanjing Agricultural University)H-Index: 1
#2Qu Chen (NAU: Nanjing Agricultural University)H-Index: 1
Last.Ruqian Zhao (NAU: Nanjing Agricultural University)H-Index: 7
view all 8 authors...
Dexamethasone (Dex), a synthetic glucocorticoid, is among the most commonly used drugs worldwide in animals and humans as an anti-inflammatory and immunosuppressive agent. GC has profound effects on plasma glucose level and other metabolic conditions. However, the effect of prolonged use of Dex on glucose metabolism in ruminants is still unclear. Ten goats were randomly assigned to two groups: the control goats were injected with saline, and the Dex-treated goats were intramuscularly injected da...
1 CitationsSource
#1Canfeng Hua (NAU: Nanjing Agricultural University)H-Index: 4
#2Yali Geng (NAU: Nanjing Agricultural University)H-Index: 4
Last.Ruqian Zhao (NAU: Nanjing Agricultural University)H-Index: 7
view all 8 authors...
Abstract Bile acids (BAs) are synthesized in the liver via the oxidation of cholesterol and further metabolized by microbiota in the gut, where they simultaneously impact gut function. In the present study, 10 goats were randomly divided into 2 groups; 1 group was injected with dexamethasone (Dex; 0.2 mg/kg), and the other group was injected with saline as the control (Con) for 21 d. Expression levels of key genes and proteins in the liver and gut mucosa were analyzed and compared to investigate...
Source
#1Canfeng Hua (NAU: Nanjing Agricultural University)H-Index: 4
#2Yali Geng (NAU: Nanjing Agricultural University)H-Index: 4
Last.Ruqian Zhao (NAU: Nanjing Agricultural University)H-Index: 7
view all 8 authors...
Source
#1Canfeng Hua (NAU: Nanjing Agricultural University)H-Index: 4
#2Yali Geng (NAU: Nanjing Agricultural University)H-Index: 4
Last.Ruqian Zhao (NAU: Nanjing Agricultural University)H-Index: 22
view all 8 authors...
Abstract The objective of this study was to investigate the effects of chronic stress induced by a low dosage of dexamethasone (Dex) on the lipolytic response in adipose tissue of goats. Ten male goats were randomly assigned to two groups; one group was injected subcutaneously with 0.2 mg/kg Dex, and the other group was injected subcutaneously with the same volume of saline as a control (Con) for 21 days. The result revealed that plasma triglycerides (TG) (P
Source
#1Qu Chen (NAU: Nanjing Agricultural University)H-Index: 1
#2Canfeng Hua (NAU: Nanjing Agricultural University)H-Index: 4
Last.Ruqian Zhao (NAU: Nanjing Agricultural University)H-Index: 7
view all 8 authors...
Abstract Chronic stress severely threatens the welfare and health of animals and humans. In order to study the effects of chronic stress on metabolism, de novo transcriptome sequencing was used to generate the expressed sequence tag dataset for the goat, using nextgeneration sequencing technology. For this study, consecutive dexamethasone (Dex) injection was used in 10 healthy male goats (body weight 25 ± 1.0 kg) to mimic chronic stress. Ten male goats were randomly assigned into two groups, one...
Source
#1Shiyu Tao (NAU: Nanjing Agricultural University)H-Index: 6
#2Liqiong Niu (NAU: Nanjing Agricultural University)H-Index: 1
Last.Ruqian Zhao (NAU: Nanjing Agricultural University)H-Index: 7
view all 7 authors...
Abstract Aims The quorum-sensing molecule N‑(3‑oxododecanoyl)‑ l ‑homoserine lactone (C12-HSL), produced by the Gram negative human pathogenic bacterium Pseudomonas aeruginosa, modulates mammalian cell behavior. Our previous findings suggested that C12-HSL rapidly decreases viability and induces apoptosis in LS174T goblet cells. Main methods In this study, the effects of 100 μM C12-HSL on mitochondrial function and cell proliferation in LS174T cells treated for 4 h were evaluated by real-time PC...
5 CitationsSource
#1Ping Tian (NAU: Nanjing Agricultural University)H-Index: 3
#2Yanwen Luo (NAU: Nanjing Agricultural University)H-Index: 4
Last.Ruqian Zhao (NAU: Nanjing Agricultural University)H-Index: 7
view all 9 authors...
Background It is well known that feeding a high concentrate (HC) diet to lactating ruminants likely induces subacute ruminal acidosis (SARA) and leads to a decrease in milk fat production. However, the effects of feeding a HC diet for long periods on milk fatty acids composition and the mechanism behind the decline of milk fat still remains poorly understood. The aim of this study was to investigate the impact of feeding a HC diet to lactating dairy goats on milk fat yield and fatty acids compos...
4 CitationsSource
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