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Sofia Ramiro
Leiden University Medical Center
Physical therapyAnkylosing spondylitisDiseaseMedicineCohort
300Publications
27H-index
6,286Citations
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Publications 319
Newest
#1Elena Nikiphorou ('KCL': King's College London)H-Index: 11
#2Sofia Ramiro (LUMC: Leiden University Medical Center)H-Index: 27
Last. D. van der Heijde (LUMC: Leiden University Medical Center)H-Index: 129
view all 6 authors...
OBJECTIVES To investigate the relationship between smoking and imaging outcomes over 5 years in axSpA and assess if socioeconomic (SE) factors influence these relationships. METHODS Patients with axSpA from the DESIR cohort were included. Four imaging outcomes (spine radiographs [modified Stoke Ankylosing Spondylitis Spine Score, mSASSS]; SIJ radiographs [modified New York grading, mNY]); MRI-Spine [Spondyloarthritis Research Consortium of Canada scoring, SPARCC] and MRI-SIJ [SPARCC]) were asses...
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#1Alexandre Sepriano (LUMC: Leiden University Medical Center)H-Index: 13
#2Sofia RamiroH-Index: 27
Last. Walter P. MaksymowychH-Index: 65
view all 30 authors...
Objective Compelling evidence supports a treat-to-target (T2T) strategy for optimal outcomes in rheumatoid arthritis (RA). There is limited knowledge regarding the factors that impede implementation of T2T, particularly in a setting where adherence to T2T is protocol specified. We aimed to assess clinical factors that associate with failure to adhere to T2T. Methods RA patients from 10 countries starting or changing conventional synthetic disease-modifying anti-rheumatic (csDMARDs) drugs and/or ...
3 CitationsSource
#1F. Hirano (Loyola University Medical Center)
#2D. van der Heijde (Loyola University Medical Center)H-Index: 4
Last. Sofia Ramiro (Loyola University Medical Center)H-Index: 27
view all 6 authors...
Background: A framework has been proposed to explain which disease outcomes impact quality of life or well-being in patients with axSpA; this was based on cross-sectional data and patients with radiographic axSpA.1 Objectives: To investigate the determinants of patient’s well-being over time, and the influence of contextual factors on these relationships in patients with early axSpA. Methods: Five-year data from DESIR, a cohort of early axSpA, were analysed. Clinical data were collected every 6 ...
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#1Alessia Alunno (University of Perugia)H-Index: 26
#2M. L. Marques (Loyola University Medical Center)
Last. P. PutrikH-Index: 1
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Background: Anti-tumour necrosis factor α (anti-TNFα) drugs infliximab (IFX) and adalimumab (ADL) are effective treatments for several rheumatic diseases. Therapeutic drug level and anti-drug antibody monitoring (TDM) has emerged as a useful tool for optimising drug effectiveness, by identifying individuals who may benefit from dose or treatment frequency adjustment, or have secondary drug failure due to immunogenicity. Objectives: Ensuring safe and effective use of biologic medicines has been i...
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#1Minne BakkerH-Index: 2
#2P. PutrikH-Index: 1
Last. Richard H. Osborne (Swinburne University of Technology)H-Index: 58
view all 13 authors...
Background: The prevalence of limited health literacy (i.e. cognitive and social resources of individuals to access, understand and apply health information to promote and maintain good health) in the Netherlands is estimated to be over 36% [1]. Access to and outcomes of rheumatological care may be compromised by limited patient health literacy, yet little is known about how to address this, thus action is required. As influencing individual patients’ health literacy in the rheumatology context ...
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#2Alexandre Sepriano (Loyola University Medical Center)H-Index: 13
Last. S. C. Barreira (HSM)
view all 17 authors...
Background: It has been common practice to start a second TNF inhibitor (TNFi) in patients with axial spondyloarthritis (axSpA) who discontinue their first TNFi. It remains unclear if the reason for discontinuation of the first TNFi influences the response to the second. Objectives: To assess if the reason of discontinuation of the first TNFi influences the response to the second TNFi. Methods: Patients with axSpA from the ReumaPt registry, who discontinued their first TNFi and started a second ...
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#1M. van OnnaH-Index: 3
#2Sofia Ramiro (Loyola University Medical Center)H-Index: 27
Last. Louise FalzonH-Index: 24
view all 11 authors...
Background: In clinical training, a portfolio is expected to stimulate learning and encourage critical reflection. Some, but not all, European countries use a portfolio in rheumatology training, and their scope varies widely. A EULAR portfolio for Rheumatology trainees could contribute to improve overall training, raise educational standards, foster the setting of common goals and harmonize rheumatology training across countries. Objectives: Develop key components that should be included in a EU...
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#1A. Najm (French Institute of Health and Medical Research)H-Index: 6
#2Alessia Alunno (University of Perugia)H-Index: 26
Last. Catherine Haines ('KCL': King's College London)H-Index: 1
view all 5 authors...
Background: In order to become a rheumatologist, trainees must successfully complete a rheumatology training program. Both the content and the assessments within these programs are regulated by national authorities, and therefore a wide heterogeneity between countries is expected. Objectives: To gain insight into current methods and practices for the assessment of competences during rheumatology training, and to explore the underlying priorities and rationales for competence assessment across EU...
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#2Remy MostardH-Index: 2
Last. Robert Landewé (LUMC: Leiden University Medical Center)H-Index: 30
view all 8 authors...
Younger patients with COVID-19 may experience an exaggerated immune response to SARS-CoV-2 infection and develop cytokine release syndrome (CRS), which may be life threatening. There is no proven antiviral therapy for COVID-19 so far, but profound immunosuppression has recently been suggested as a treatment for COVID-19-associated CRS. We present a case of life-threatening CRS caused by COVID-19 infection with a favourable response to immunosuppressive therapy with tocilizumab (TCZ). The rapid c...
2 CitationsSource
#1Alexandre Sepriano (NOVA: Universidade Nova de Lisboa)H-Index: 13
#2Sofia Ramiro (LUMC: Leiden University Medical Center)H-Index: 27
Last. Robert Landewé (UvA: University of Amsterdam)H-Index: 30
view all 4 authors...
Zeidler and Hudson1 break a lance on the entity of reactive arthritis when dealing with classification criteria for spondyloarthritis (SpA), axial or peripheral. We would like to thank our colleagues for their insightful comments and reassure them that we do not forget reactive arthritis as an entity or put it aside. It is important to make clear that Zeidler and Hudson argue about a causal …
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