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Antonio Fraioli
Sapienza University of Rome
55Publications
11H-index
600Citations
Publications 55
Newest
#1Ilaria Barchetta (Sapienza University of Rome)H-Index: 12
#2Valentina Ceccarelli (Sapienza University of Rome)H-Index: 5
Last.Maria Gisella Cavallo (Sapienza University of Rome)H-Index: 23
view all 9 authors...
Purpose Osteopontin (OPN), osteoprotegerin (OPG) and osteocalcin (OC) are matrix glycoproteins which mediate bone mineralization; moreover, their effects on glucose/insulin homeostasis have recently been demonstrated. Higher circulating OPN and OPG levels have been associated with the presence of insulin resistance, atherosclerosis and coronary heart disease. No data are available on contextual changes of these markers in type 2 diabetes mellitus (T2DM). Therefore, aims of this study were to eva...
2 CitationsSource
#1Antonio Fraioli (Policlinico Umberto I)H-Index: 11
#2G Mennuni (Policlinico Umberto I)H-Index: 13
Last.Serio A (Università Campus Bio-Medico)H-Index: 4
view all 7 authors...
Background. Osteoarthritis (OA) is the most common musculoskeletal disease in the world. OA is the result of an inflammatory and degenerative process affecting the entire joint. Osteoarthritis, especially involving the knee, has a relevant socioeconomic impact in terms of drugs, hospital admissions, work absences, and temporary or permanent invalidity. Therapy of knee osteoarthritis is based on pharmacological and nonpharmacological measures. Methods. We conducted a systematic review of the stud...
4 CitationsSource
#1Ilaria BarchettaH-Index: 12
#2M. Del BenH-Index: 1
Last.Maria Gisella CavalloH-Index: 23
view all 16 authors...
Source
#1Marco Paoloni (Sapienza University of Rome)H-Index: 18
#2Andrea Bernetti (Sapienza University of Rome)H-Index: 7
Last.Valter Santilli (Sapienza University of Rome)H-Index: 26
view all 13 authors...
Objective . The aim of the study was to identify the main aspects concerning appropri-ateness and efficacy of Spa therapy for musculoskeletal pathologies. Methods . A committee of 8 experts from Italian universities, public hospitals, territorial services, research institutes and patient associations was set up. Clinicians from Italian medical centers specialized in rheumatology, rehabilitation and thermal medicine took part in a Delphi process aimed at obtaining consensus statements among the p...
11 CitationsSource
#1Ilaria Barchetta (Sapienza University of Rome)H-Index: 12
#2M. Del Ben (Sapienza University of Rome)H-Index: 25
Last.Maria Gisella Cavallo (Sapienza University of Rome)H-Index: 23
view all 16 authors...
Non-alcoholic fatty liver disease (NAFLD) is the most common hepatic disorder worldwide, reaching prevalence up to 90 % in obese patients with type 2 diabetes (T2D), and representing an independent risk factor for cardiovascular mortality. Furthermore, the coexistence of T2D and NAFLD leads to higher incidence of diabetes’ complications and additive detrimental liver outcomes. The existence of a close association between NAFLD and hypovitaminosis D, along with the anti-inflammatory and insulin-s...
45 CitationsSource
#1Ilaria BarchettaH-Index: 12
#2Francesco AngelicoH-Index: 31
Last.Maria Gisella CavalloH-Index: 23
view all 13 authors...
Adipose tissue (AT) inflammation leads to increased free fatty acid (FFA) efflux and ectopic fat deposition, but whether AT dysfunction drives selective fat accumulation in specific sites remains unknown. The aim of the present study was to investigate the correlation between AT dysfunction, hepatic/pancreatic fat fraction (HFF, PFF) and the associated metabolic phenotype in patients with Type 2 diabetes (T2D). Sixty-five consecutive T2D patients were recruited at the Diabetes Centre of Sapienza...
7 CitationsSource
#1Ilaria Barchetta (Sapienza University of Rome)H-Index: 12
#2Cristiano Alessandri (Sapienza University of Rome)H-Index: 30
Last.Maria Gisella Cavallo (Sapienza University of Rome)H-Index: 23
view all 9 authors...
Osteopontin (OPN) is a sialoprotein implicated in different immunity and metabolic pathways. Capable of activating dendritic cells and inducing Th1-Th17-mediated tissue damage, OPN plays a significant role in the development/progression of several autoimmune diseases; interestingly, it was also shown that OPN participates in the acute pancreatic islets response to experimentally induced diabetes in non-obese diabetic (NOD) mice. Furthermore, OPN promotes adipose tissue dysfunction, systemic infl...
12 CitationsSource
#1Ilaria BarchettaH-Index: 12
#2F. AngelicoH-Index: 5
Last.Maria Gisella CavalloH-Index: 23
view all 14 authors...
1 CitationsSource
#1Ilaria Barchetta (Sapienza University of Rome)H-Index: 12
#2Marco Giorgio Baroni (Sapienza University of Rome)H-Index: 30
Last.Maria Gisella Cavallo (Sapienza University of Rome)H-Index: 23
view all 9 authors...
A circannual periodicity in thyrotropin (TSH) secretion has been reported but the causes of these phenomenon are still undefined. Vitamin D exerts a direct influence on pituitary axes including the hypothalamus–pituitary–thyroid axis. Aims of the present study were to investigate the presence of a seasonal variability of TSH secretion and to study the association between vitamin D status and TSH levels in a population of euthyroid adults. For this purpose, we recruited 294 euthyroid adults (M/F ...
7 CitationsSource
#1G MennuniH-Index: 13
#2Serio AH-Index: 4
Last.Antonio FraioliH-Index: 11
view all 8 authors...
The prevalence and incidence of nephrolithiasis is reported to be increasing across the world. It is a disease of increased urinary concentration of stone-forming salts. The physicochemical mechanism of stone formation includes precipitation, homogenous/heterogeneous nucleation, growth, aggregation and concretion of various modulators in urine. Necessary condition to develop stones is urinary supersaturation, due to reduced urinary volume or to an excesses solutes. Fluid intake is the main deter...
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