Match!
Adrianna Vlachos
North Shore-LIJ Health System
Molecular biologyDiamond–Blackfan anemiaGeneticsMedicineBiology
37Publications
16H-index
1,925Citations
What is this?
Publications 52
Newest
Patients with sickle cell disease (SCD) are theoretically at greater risk for serious illness from COVID 19 due to the underlying pathophysiology of chronic inflammation with an increased risk of thrombosis, especially at the time of a vaso-occlusive event (1). Individuals living with SCD are also considered to be immunocompromised due to autoinfarction of their spleen or surgical splenectomy, often as a result of red cell splenic sequestration (2). In addition, patients with SCD often have como...
Source
#1Ryan Ashley (Hofstra University)H-Index: 1
#2Hongxia Yan (University of Montpellier)
Last. Adrianna Vlachos (Hofstra University)H-Index: 16
view all 18 authors...
Despite the effective clinical use of steroids for the treatment of Diamond Blackfan anemia (DBA), the mechanisms through which glucocorticoids regulate human erythropoiesis remain poorly understood. We report that the sensitivity of erythroid differentiation to dexamethasone is dependent on the developmental origin of human CD34+ progenitor cells, specifically increasing the expansion of CD34+ progenitors from peripheral blood (PB) but not cord blood (CB). Dexamethasone treatment of erythroid-d...
1 CitationsSource
#1Ryan Ashley (The Feinstein Institute for Medical Research)
#2Hongxia Yan (NYBC: New York Blood Center)H-Index: 5
Last. Adrianna VlachosH-Index: 16
view all 18 authors...
Source
#1Adrianna Vlachos (Hofstra University)H-Index: 16
#2Evangelia Atsidaftos (The Feinstein Institute for Medical Research)H-Index: 2
Last. Jeffrey M. Lipton (The Feinstein Institute for Medical Research)H-Index: 39
view all 17 authors...
Source
#1Jimmy HomH-Index: 3
#2Brian M. DulmovitsH-Index: 3
Last. Lionel BlancH-Index: 20
view all 6 authors...
Source
#1Adrianna VlachosH-Index: 16
#2Diana S. OsorioH-Index: 3
Last. Jeffrey M. LiptonH-Index: 1
view all 16 authors...
#1Jens LichtenbergH-Index: 11
#2Jason E. Farrar (University of Arkansas for Medical Sciences)H-Index: 14
Last. David M. Bodine (NIH: National Institutes of Health)H-Index: 50
view all 9 authors...
Source
#1Adrianna Vlachos (Hofstra University)H-Index: 16
#2Philip S. Rosenberg (NIH: National Institutes of Health)H-Index: 60
Last. Jeffrey M. Lipton (Hofstra University)H-Index: 39
view all 6 authors...
Diamond Blackfan anemia (DBA) is an inherited bone marrow failure syndrome (IBMFS) characterized by red cell aplasia and congenital anomalies. In our 2012 report the predisposition to cancer was quantified for the first time by the DBA Registry of North America (DBAR), the largest established DBA patient cohort with prospective follow-up since 1991. Five years from the original analysis, this update of the cancer incidence in patients with DBA reveals additional solid tumors, in particular gastr...
7 CitationsSource
#1Amit Lahoti (Hofstra University)H-Index: 2
#2Yael T. Harris (Hofstra University)H-Index: 6
Last. Adrianna Vlachos (Hofstra University)H-Index: 16
view all 6 authors...
Background Diamond–Blackfan anemia (DBA) is a rare inherited bone marrow failure syndrome. The mainstays of treatment involve chronic red cell transfusions, long-term glucocorticoid therapy, and stem cell transplantation. Systematic data concerning endocrine function in DBA are limited. We studied patients in the DBA Registry (DBAR) of North America to assess the prevalence of various endocrinopathies. Procedure In a pilot study, retrospective data were collected for 12 patients with DBA. Subseq...
6 CitationsSource
#1Adrianna VlachosH-Index: 16
#2Jeffrey M. LiptonH-Index: 1
This chapter describes the causes, clinical manifestations, diagnosis and treatment of various types of both acquired and inherited bone marrow failure syndromes.
Source
123456