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Ana M. Troncoso
University of Seville
ChemistryFood scienceChromatographyBiochemistryWine
136Publications
35H-index
4,089Citations
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Publications 138
Newest
#1Cristina Úbeda (University of Seville)H-Index: 10
#2Ruth Hornedo-Ortega (University of Bordeaux)H-Index: 2
Last. Ana M. Troncoso (University of Seville)H-Index: 35
view all 5 authors...
Abstract Climate change has an impact on the chemical risks associated to wine consumption related with grape development and microbial contamination. We can classify chemical hazards in wine into two groups: those present in grapes due to agricultural practices, environmental contamination or fungal growth and those coming from fermentation and the winemaking process. The first group includes mycotoxins, whilst the second encompasses ethyl carbamate, biogenic amines, sulfur dioxide and proteins...
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Neuroinflammation is a common feature shared by neurodegenerative disorders, such as Parkinson’s disease (PD), and seems to play a key role in their development and progression. Microglia cells, the principal orchestrators of neuroinflammation, can be polarized in different phenotypes, which means they are able to have anti-inflammatory, pro-inflammatory, or neurodegenerative effects. Increasing evidence supports that the traditional Mediterranean dietary pattern is related to the reduction of c...
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#1M. Antonia Álvarez-Fernández (University of Seville)H-Index: 7
#2E. Fernández-Cruz (University of Seville)H-Index: 4
Last. M. Carmen Garcia-Parrilla (University of Seville)H-Index: 17
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Abstract Yeast nitrogen metabolism produces metabolites, whose origin in wines has scarcely been studied, with an important biological and organoleptic role. The present work focuses on comparing three intracellular extraction methods in order to elucidate efficiency of extraction while measuring the effect of temperature upon the integrity of the compounds related to the metabolism of tryptophan and tyrosine by yeast. Two UHPLC/HRMS methods to measure 16 metabolites were developed and validated...
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#1Ana B. CerezoH-Index: 17
#2María LabradorH-Index: 1
Last. M. Carmen Garcia-ParrillaH-Index: 17
view all 6 authors...
Angiogenesis drives evolution and destabilisation of atherosclerotic plaques and the growth and expansion of tumour cells. Vascular endothelial growth factor (VEGF) is the main endogenous pro-angiogenic factor in humans. The aim was to provide insight into the anti-VEGF activity of bioactive compounds derived from aromatic amino acids (serotonin, melatonin, 3-indoleacetic acid, 5-hydroxytryptophol and hydroxytyrosol). Experiments involved endothelial cell migration (wound-healing assay), the mol...
1 CitationsSource
#1Marta Gallardo-Fernández (University of Seville)
#2Ruth Hornedo-Ortega (University of Bordeaux)H-Index: 2
Last. M. Carmen Garcia-Parrilla (University of Seville)H-Index: 17
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Abstract Preventing the abnormal assembly of α-synuclein (α-Syn) and the correct modulation of vitagenes system exercise strong neuroprotective effects. It has been reported that melatonin (MEL), protocatechuic acid (PCA) and hydroxytyrosol (HT) reduce α-Syn toxicity. Their effect on the vitagenes system of PC12 cells have not been explored yet. These bioactive can cross the blood brain barrier (BBB). Therefore, this work aims to evaluate the inhibitory and destabilising capacities of MEL, PCA, ...
3 CitationsSource
#1Eva GesteiroH-Index: 5
Last. Marcela González-GrossH-Index: 46
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Internationally recognized Spanish experts in the food industry, nutrition, toxicology, sustainability, and veterinary science met in Madrid on July 2018 to develop a consensus about palm oil (PO) as a food ingredient. Their aim was to provide a useful, evidence-based point of reference about PO. Scientific evidence about the role of PO in food safety, nutrition and sustainability was analyzed. Main conclusions were: (1) RSPO foundation responded to the environmental impact of palm crops. The Am...
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#1M. Antonia Álvarez-Fernández (University of Seville)H-Index: 7
#2E. Fernández-Cruz (University of Seville)H-Index: 4
Last. Panagiotis ArapitsasH-Index: 15
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Tryptophan, phenylalanine, and tyrosine play an important role as nitrogen sources in yeast metabolism. They regulate biomass production and fermentation rate, and their catabolites contribute to wine health benefits and sensorial character through the yeast biotransformation of grape juice constitutes into biologically active and flavor-impacting components. A UHPLC-MS/MS method was applied to monitor 37 tryptophan/phenylalanine/tyrosine yeast metabolites both in extra- and intracellular extrac...
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#1E. Fernández-Cruz (University of Seville)H-Index: 4
#2Ana B. Cerezo (University of Seville)H-Index: 17
Last. M. Carmen Garcia-Parrilla (University of Seville)H-Index: 17
view all 6 authors...
Stilbenes are phenolic compounds present in different higher plant families that have shown different biological activities, such as antioxidant properties and antitumoral and anti-atherosclerotic effects, among others. Angiogenesis is a key process involved in both cancer and cardiovascular diseases, the vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 being the main triggers. Certain polyphenol compounds, such as flavonoids, have shown a potent capacity to inhibit VEGF and, c...
1 CitationsSource
#1E. Fernández-Cruz (University of Seville)H-Index: 4
#2Beatriz GonzálezH-Index: 6
Last. José Manuel Guillamón (CSIC: Spanish National Research Council)H-Index: 40
view all 9 authors...
Certain bioactive compounds that derive from tryptophan have been determined in fermented foods, which suggests that the role of yeast is putative in origin. Melatonin is a neurohormone in humans that plays an important role in health. The activity of other compounds, such as 3-indoleacetic acid, has been recently highlighted, and interest in elucidating the conditions of their production has grown. However, the biosynthesis of melatonin by yeasts remains unclear to a large extent. Therefore, th...
1 CitationsSource
#1E. Fernández-Cruz (University of Seville)H-Index: 4
#2Ana B. Cerezo (University of Seville)H-Index: 17
Last. María Carmen García-Parrilla (University of Seville)H-Index: 25
view all 5 authors...
5 CitationsSource
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