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Niccolo Camarlinghi
University of Pisa
PhysicsBeam (structure)Medical physicsProton therapyDetector
81Publications
12H-index
608Citations
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Publications 82
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Abstract FOOT (FragmentatiOn On Target) is an applied nuclear physics experiment aimed at measuring the production cross sections of fragments for energies, beams and targets relevant in particle therapy and radioprotection in space. The Δ E-TOF detector will measure the energy deposited by the fragments in a wall of plastic scintillators and the time of flight with respect to a start detector. These two quantities allow to determine the charge Z of the fragment. In this work, we summarize the c...
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#1A. Topi (INFN: Istituto Nazionale di Fisica Nucleare)
#2S. Muraro (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 7
Last. Valeria Rosso (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 18
view all 17 authors...
In this work, we investigate the use of a PET system to monitor the proton therapy. The monitoring procedure is based on the comparison between the β+activity generated in the irradiated volume during the treatment, with the β+activity distribution obtained with Monte Carlo simulation. The dedicated PET system is a dual head detection system; each head is composed of nine scintillating LYSO crystal matrices read out independently with a custom modularized acquisition system. Our experimental dat...
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#1Ilaria MatteiH-Index: 10
view all 96 authors...
In a carbon ion treatment the nuclear fragmentation of both target and beam projectiles impacts on the dose released on the tumor and on the surrounding healthy tissues. Carbon ion fragmentation occurring inside the patient body has to be studied in order to take into account this contribution. These data are also important for the development of the range monitoring techniques with charged particles. The production of charged fragments generated by carbon ion beams of 115–353 MeV/u kinetic ener...
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#1L. Galli (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 2
#2A.C. Kraan (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 4
Last. Maria Giuseppina Bisogni (UniPi: University of Pisa)H-Index: 18
view all 16 authors...
Abstract Nuclear physics processes are an important source of uncertainty in dose calculations in particle therapy and radioprotection in space. Accurate cross section measurements are a crucial ingredient in improving the understanding of these processes. The FOOT (FragmentatiOn Of Target) experiment aims at measuring the production cross sections of fragments for energies, beams and targets that are relevant in particle therapy and radioprotection in space. An experimental apparatus composed o...
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#1S. Muraro (UniPi: University of Pisa)H-Index: 1
#2Niccolo Camarlinghi (UniPi: University of Pisa)H-Index: 12
Last. Valeria Rosso (UniPi: University of Pisa)H-Index: 18
view all 17 authors...
Abstract Positron emission tomography (PET) is one of the most mature techniques for monitoring in ion beam therapy. PET allows to reconstruct the β + activity generated in the patient by the nuclear interaction of the ions. Taking advantage of the spatial correlation between positron emitters created along the ions path and the dose distribution, it is possible to perform a quality control of the treatment. Usually, to reconstruct the activity generated within the irradiated volume, standard 3D...
1 CitationsSource
#1Esther Ciarrocchi (UniPi: University of Pisa)H-Index: 4
#2Nicola Belcari (UniPi: University of Pisa)H-Index: 21
Last. Maria Giuseppina Bisogni (UniPi: University of Pisa)H-Index: 18
view all 14 authors...
Abstract The FOOT experiment aims at identifying the fragments produced in the human body during hadrontherapy and at measuring their cross sections. The apparatus is composed of several detectors which allow a complete reconstruction of the tracks of the fragments. In particular, the Δ E-TOF detector measures the energy released in a thin plastic scintillator and the time of flight of the fragments. In this work, we report the energy and time resolution of a Δ E-TOF detector prototype with prot...
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#1S.M. Valle (INFN: Istituto Nazionale di Fisica Nucleare)
#2A. AlexandrovH-Index: 6
Last. Antonio Zoccoli (UNIBO: University of Bologna)H-Index: 85
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Abstract Particle therapy uses proton or 12 C beams to treat deep-seated solid tumors. Due to the advantageous characteristics of charged particles energy deposition in matter, the maximum of the dose is released to the tumor at the end of the beam range, in the Bragg peak region. However, the beam nuclear interactions with the patient tissues induces fragmentation both of projectile and target nuclei and needs to be carefully taken into account. In proton treatments, the target fragmentation pr...
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#2Adele LauriaH-Index: 20
Last. G. De LellisH-Index: 23
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#1Nicola Belcari (UniPi: University of Pisa)H-Index: 21
#2Maria Giuseppina Bisogni (UniPi: University of Pisa)H-Index: 18
Last. Alberto Del Guerra (UniPi: University of Pisa)H-Index: 31
view all 9 authors...
The TRIMAGE project aims at developing a brain-dedicated PET/MR/EEG system able to perform simultaneous PET, MR, and EEG acquisitions for application in schizophrenia. Both PET and MR components have been designed in this project. The PET component consists of a full ring with 18 sectors each comprising three square detector modules. The modules are based on dual-layer staggered matrices of LYSO crystals read out by silicon photomultipliers. This paper describes in full detail the final version ...
2 CitationsSource
#1A.C. KraanH-Index: 4
#2S. MuraroH-Index: 7
Last. Valeria RossoH-Index: 18
view all 17 authors...
Background: Treatment verification with PET imaging in charged particle therapy is conventionally done by comparing measurements of spatial distributions with Monte Carlo (MC) predictions. However, decay curves can provide additional independent information about the treatment and the irradiated tissue. Most studies performed so far focus on long time intervals. Here we investigate the reliability of MC predictions of space and time (decay rate) profiles shortly after irradiation, and we show ho...
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