Match!
Hongyi Kang
University of Rochester Medical Center
10Publications
6H-index
1,782Citations
Publications 10
Newest
Published on May 1, 2019in Journal of Neurosurgery
Benjamin A. Plog10
Estimated H-index: 10
(URMC: University of Rochester Medical Center),
Nanhong Lou12
Estimated H-index: 12
+ 7 AuthorsG. Edward Vates16
Estimated H-index: 16
Published on Sep 1, 2016in Journal of Cerebral Blood Flow and Metabolism6.04
McConnell Ed1
Estimated H-index: 1
(URMC: University of Rochester Medical Center),
Helen S. Wei4
Estimated H-index: 4
(URMC: University of Rochester Medical Center)
+ 4 AuthorsNedergaard M1
Estimated H-index: 1
(URMC: University of Rochester Medical Center)
Aneurysmal subarachnoid hemorrhage remains one of the more devastating forms of stroke due in large part to delayed cerebral ischemia that appears days to weeks following the initial hemorrhage. Therapies exclusively targeting large caliber arterial vasospasm have fallen short, and thus we asked whether capillary dysfunction contributes to delayed cerebral ischemia after subarachnoid hemorrhage. Using a mouse model of subarachnoid hemorrhage and two-photon microscopy we showed capillary dysfunct...
Published on Nov 1, 2015in Nature Communications11.88
Iben Lundgaard5
Estimated H-index: 5
,
Baoman Li4
Estimated H-index: 4
+ 9 AuthorsMichael L. Nielsen24
Estimated H-index: 24
The brain is a highly active organ that relies almost exclusively on glucose as its energy source, but whether glucose is directly taken up by neurons or whether it is converted to lactate by astrocytes before neuronal uptake is still unclear. Here the authors perform in vivo imaging in awake mice and show evidence in support of the direct uptake of glucose by neurons.
Published on Aug 1, 2015in Neurosurgery4.61
Helen S. Wei4
Estimated H-index: 4
,
Izad-Yar D. Rasheed2
Estimated H-index: 2
+ 4 AuthorsG. Edward Vates16
Estimated H-index: 16
Published on Feb 1, 2015in Stroke6.05
Helen S. Wei1
Estimated H-index: 1
(UR: University of Rochester),
Takahiro Takano39
Estimated H-index: 39
(UR: University of Rochester)
+ 6 AuthorsG. Edward Vates2
Estimated H-index: 2
(UR: University of Rochester)
Activity-dependent increases in blood flow comprise the basis for functional brain imaging and are considered a hallmark of normal brain function. The central dogma of blood flow regulation states that flow changes effected by arteriolar tone drive functional hyperemia and that the capillary bed is a passive conduit for hyperemia resulting from upstream vasodilation. Recent evidence has begun to challenge this convention in cerebral blood flow control and suggests that pericytes may dilate capil...
Published on Dec 1, 2014in Annals of Neurology9.50
Benjamin T. Kress10
Estimated H-index: 10
(UR: University of Rochester),
Jeffrey J. Iliff24
Estimated H-index: 24
(UR: University of Rochester)
+ 10 AuthorsJason Liew1
Estimated H-index: 1
(UR: University of Rochester)
Objective: In the brain, protein waste removal is partly performed by paravascular pathways that facilitate convective exchange of water and soluble contents between cerebrospinal fluid (CSF) and interstitial fluid (ISF). Several lines of evidence suggest that bulk flow drainage via the glymphatic system is driven by cerebrovascular pulsation, and is dependent on astroglial water channels that line paravascular CSF pathways. The objective of this study was to evaluate whether the efficiency of C...
Published on May 1, 2014in Journal of Neuroscience Methods2.79
Benjamin A. Plog10
Estimated H-index: 10
(UR: University of Rochester),
Katherine Moll2
Estimated H-index: 2
(UR: University of Rochester)
+ 3 AuthorsG. Edward Vates16
Estimated H-index: 16
(URMC: University of Rochester Medical Center)
Background Subarachnoid hemorrhage (SAH) is a neurologic catastrophe and poor outcome is typically attributed to vasospasm; however, there is also evidence that SAH causes a pro-inflammatory state and these two phenomena may be interrelated. SAH causes activation of microglia, but the time course and degree of microglial activation after SAH and its link to poor patient outcome and vasospasm remains unknown.
Published on Jan 1, 2014
Lulu Xie4
Estimated H-index: 4
,
Hongyi Kang6
Estimated H-index: 6
+ 6 AuthorsTakahiro Takano39
Estimated H-index: 39
Published on Dec 1, 2013in Cell Calcium3.93
Fengfei Ding1
Estimated H-index: 1
(URMC: University of Rochester Medical Center),
John O’Donnell3
Estimated H-index: 3
(URMC: University of Rochester Medical Center)
+ 4 AuthorsFushun Wang15
Estimated H-index: 15
(URMC: University of Rochester Medical Center)
Astrocyte Ca2+ signals in awake behaving mice are widespread, coordinated and differ fundamentally from the locally restricted Ca2+ transients observed ex vivo and in anesthetized animals. Here we show that the synchronized release of norepinephrine (NE) from locus coeruleus (LC) projections throughout the cerebral cortex mediate long-ranging Ca2+ signals by activation of astrocytic α1-adrenergic receptors. When LC output was triggered by either physiological sensory (whisker) stimulation or an ...
Published on Oct 18, 2013in Science41.04
Lulu Xie4
Estimated H-index: 4
(URMC: University of Rochester Medical Center),
Hongyi Kang6
Estimated H-index: 6
(URMC: University of Rochester Medical Center)
+ 9 AuthorsJeffrey J. Iliff24
Estimated H-index: 24
(URMC: University of Rochester Medical Center)
The conservation of sleep across all animal species suggests that sleep serves a vital function. We here report that sleep has a critical function in ensuring metabolic homeostasis. Using real-time assessments of tetramethylammonium diffusion and two-photon imaging in live mice, we show that natural sleep or anesthesia are associated with a 60% increase in the interstitial space, resulting in a striking increase in convective exchange of cerebrospinal fluid with interstitial fluid. In turn, conv...
1