Match!
Adrian Gericke
University of Mainz
OphthalmologyEndocrinologySurgeryMedicineBiology
79Publications
12H-index
508Citations
What is this?
Publications 80
Newest
#1Verena Prokosch (WWU: University of Münster)H-Index: 10
#1Verena Prokosch (WWU: University of Münster)H-Index: 2
Last. Solon Thanos (WWU: University of Münster)H-Index: 30
view all 8 authors...
PURPOSE: Pathological alterations within optic nerve axons and progressive loss of the parental retinal ganglion cell (RGC) bodies are characteristics of glaucomatous neuropathy. Abnormally elevated intraocular pressure (IOP) is thought to be the major risk factor for most forms of glaucomatous changes, while lowering of the IOP is the mainstream of treatment. However, the pathophysiological mechanisms involved in neurodegenerative changes are poorly understood. It remains still a matter of deba...
1 CitationsSource
#1Jana C. RiedlH-Index: 1
Last. Adrian GerickeH-Index: 12
view all 6 authors...
To evaluate changes of anterior and posterior corneal astigmatism after superficial keratectomy in peripheral hypertrophic subepithelial corneal opacification (PHSCO). Patients with PHSCO, who had ...
Source
#1Aytan Musayeva (University of Mainz)H-Index: 3
#2Adrian Gericke (University of Mainz)H-Index: 12
Last. Gerd GeerlingH-Index: 38
view all 11 authors...
The Sicca-Forderpreis (Dry Eye Award) supports the development of scientific research on the pathogenesis, diagnostics, and treatment of dry eye and ocular surface diseases. It is awarded after a limited call for proposals in German-speaking countries, written application and selection of the award winner after evaluation by a jury of ophthalmologists working in basic and clinical science. In this article examples of the results of funded projects of the Sicca-Forderpreis 2016 are cursorily desc...
Source
#1Jana C. Riedl (University of Mainz)H-Index: 1
#2Aytan Musayeva (University of Mainz)H-Index: 3
Last. Adrian Gericke (University of Mainz)H-Index: 12
view all 5 authors...
Background/aim To describe the clinical outcome of allogenic simple limbal epithelial transplantation (alloSLET) utilising tissue from cadaveric donor eyes after failed re-epithelialisation of the corneal surface. Methods Medical records of 14 eyes from 14 patients treated for persistent corneal epithelial defects with alloSLET were reviewed. The primary outcome measure was complete epithelialisation of the corneal surface. Secondary outcome measures were best corrected visual acuity (BCVA) and ...
Source
#1Aytan Musayeva (University of Mainz)H-Index: 3
#2Jana C. RiedlH-Index: 1
Last. Adrian GerickeH-Index: 12
view all 6 authors...
PURPOSE: Voriconazole was shown to inhibit ergosterol synthesis in various acanthamoeba species. The purpose of this study was to evaluate the clinical outcome of treatment with supplemental topical voriconazole in patients with acanthamoeba keratitis (AK). METHODS: All patients who had been treated for AK with voriconazole 1% drops in conjunction with topical first-line antiacanthamoeba therapy composed of polyhexamethylene biguanide (PHMB) 0.02% and propamidine isethionate 0.1% (Brolene) betwe...
Source
PURPOSE: To characterize the corneal changes in peripheral hypertrophic subepithelial corneal opacification (PHSCO) considering elevation of the anterior and posterior corneal surface, corneal astigmatism, tear secretion, and endothelial cell density. METHODS: Thirty-eight eyes of 22 patients with PHSCO on at least 1 eye and 38 eyes of 22 age- and sex-matched healthy subjects were included in this retrospective cross-sectional study. Using the Pentacam system (Oculus, Wetzlar, Germany), measurem...
Source
#1Verena Prokosch-Willing (University of Mainz)H-Index: 4
#2Karl Mercieca (University of Manchester)H-Index: 1
Last. Adrian Gericke (University of Mainz)H-Index: 12
view all 4 authors...
Source
#1Adrian Gericke (University of Mainz)H-Index: 12
#2Carolina Mann (University of Mainz)H-Index: 3
Last. Verena Prokosch (University of Mainz)H-Index: 2
view all 11 authors...
Objective. Glaucoma is a leading cause of severe visual impairment and blindness. Although high intraocular pressure (IOP) is an established risk factor for the disease, the role of abnormal ocular vessel function in the pathophysiology of glaucoma gains more and more attention. We tested the hypothesis that elevated intraocular pressure (IOP) causes vascular dysfunction in the retina. Methods. High IOP was induced in one group of mice by unilateral cauterization of three episcleral veins. The o...
4 CitationsSource
#1Xiaohong Wang (University of Mainz)H-Index: 33
#2Adrian Gericke (University of Mainz)H-Index: 12
Last. Werner E. G. Müller (University of Mainz)H-Index: 67
view all 8 authors...
The regeneration of the epithelium, covering the avascular cornea, involves the processes of differentiation, proliferation and migration of cells originating from the corneal epithelial stem cells. We ask the question if these energy-consuming processes can be fueled by the physiological, inorganic polyphosphate (polyP), the main energy storage/donor molecule in the extracellular space. The ex vivo results reveal that addition of polyP, in the form of soluble Na-polyP, to the culture medium eli...
Source
#1Jenia Kouchek Zadeh (University of Mainz)H-Index: 3
#2Mayagozel B. Zhutdieva (University of Mainz)H-Index: 1
Last. Adrian Gericke (University of Mainz)H-Index: 12
view all 12 authors...
Objective. Atherogenic lipoproteins may impair vascular reactivity consecutively causing tissue damage in multiple organs via abnormal perfusion and excessive reactive oxygen species generation. We tested the hypothesis that chronic hypercholesterolemia causes endothelial dysfunction and cell loss in the retina. Methods. Twelve-month-old apolipoprotein E-deficient (ApoE-/-) mice and age-matched wild-type controls were used in this study ( per genotype for each experiment). Intraocular pressure, ...
1 CitationsSource
12345678