Amelie M. Lutz
Stanford University
RadiologyMolecular imagingPathologyMagnetic resonance imagingMedicine
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Publications 64
#1Rakesh Bam (Stanford University)H-Index: 5
#2Patrick S. Lown (UMN: University of Minnesota)H-Index: 2
Last. Lotfi Abou-Elkacem (Stanford University)H-Index: 5
view all 11 authors...
Purpose: Human B7-H3 (hB7-H3) is a promising molecular imaging target differentially expressed on the neovasculature of breast cancer and has been validated for pre-clinical ultrasound (US) imaging with anti-B7-H3-antibody functionalized microbubbles (MB). However, smaller ligands such as affibodies (ABY) are more suitable for the design of clinical-grade targeted-MB. Experimental Design: Binding of ABYB7-H3 was confirmed with soluble and cell-surface B7-H3 by flow-cytometry. MB were functionali...
#1Huaijun WangH-Index: 18
Last. Ramasamy PaulmuruganH-Index: 33
view all 8 authors...
#1Simona Turco (TU/e: Eindhoven University of Technology)H-Index: 4
#2Ahmed El Kaffas (Stanford University)H-Index: 9
Last. Massimo Mischi (TU/e: Eindhoven University of Technology)H-Index: 26
view all 7 authors...
Purpose To evaluate quantitative and semi-quantitative ultrasound molecular imaging (USMI) for antiangiogenic therapy monitoring in human colon cancer xenografts in mice.
#1Huaijun WangH-Index: 18
#2Jean-Marc HyvelinH-Index: 6
Last. Jürgen K. WillmannH-Index: 42
view all 10 authors...
Our study suggests that US molecular imaging using clinically translatable dual-selectin–targeted microbubbles allows reliable noninvasive monitoring of anti-inflammatory treatment effects in a swi...
#1Huaijun Wang (Stanford University)H-Index: 18
#2Stephen A. Felt (Stanford University)H-Index: 11
Last. Jürgen K. Willmann (Stanford University)H-Index: 42
view all 15 authors...
Objectives To evaluate the feasibility and time saving of fusing CT and MR enterography with ultrasound for ultrasound molecular imaging (USMI) of inflammation in an acute small bowel inflammation of swine.
#1Adam L. Bartret (Stanford University)H-Index: 1
#2Christopher F. Beaulieu (Stanford University)H-Index: 42
Last. Amelie M. Lutz (Stanford University)H-Index: 26
view all 3 authors...
Objectives To investigate the purported relationship between sciatic nerve variant anatomy and piriformis syndrome.
3 CitationsSource
#1Daehyun Yoon (Stanford University)H-Index: 6
#2Sandip Biswal (Stanford University)H-Index: 21
Last. Brian A. Hargreaves (Stanford University)H-Index: 38
view all 5 authors...
2 CitationsSource
#1Jianhua ZhouH-Index: 3
#2Huiping Zhang (Stanford University)H-Index: 2
Last. Jürgen K. Willmann (Stanford University)H-Index: 42
view all 8 authors...
Due to spatial tumor heterogeneity and consecutive sampling errors, it is critically important to assess treatment response following antiangiogenic therapy in three dimensions as two-dimensional assessment has been shown to substantially over- and underestimate treatment response. In this study, we evaluated whether three-dimensional (3D) dynamic contrast-enhanced ultrasound (DCE-US) imaging allows assessing early changes in tumor perfusion following antiangiogenic treatment (bevacizumab admini...
14 CitationsSource
#1Jürgen K. WillmannH-Index: 42
#2Lorenzo BonomoH-Index: 46
Last. Sanjiv S. GambhirH-Index: 115
view all 10 authors...
PurposeWe performed a first-in-human clinical trial on ultrasound molecular imaging (USMI) in patients with breast and ovarian lesions using a clinical-grade contrast agent (kinase insert domain receptor [KDR] –targeted contrast microbubble [MBKDR]) that is targeted at the KDR, one of the key regulators of neoangiogenesis in cancer. The aim of this study was to assess whether USMI using MBKDR is safe and allows assessment of KDR expression using immunohistochemistry (IHC) as the gold standard.Me...
47 CitationsSource
#1Vanja Varenika (UCSF: University of California, San Francisco)H-Index: 6
#2Amelie M. Lutz (Stanford University)H-Index: 26
Last. Matthew D. Bucknor (UCSF: University of California, San Francisco)H-Index: 10
view all 4 authors...
Objective To determine whether known variant anatomical relationships between the sciatic nerve and piriformis muscle can be identified on routine MRI studies of the hip and to establish their imaging prevalence.
7 CitationsSource