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Dario Stupar
Queensland University of Technology
8Publications
2H-index
12Citations
Publications 8
Newest
Published on Apr 21, 2017in Advances in wound care
L FernandezMelissa1
Estimated H-index: 1
,
StuparDario1
Estimated H-index: 1
+ 2 AuthorsUptonZee1
Estimated H-index: 1
Significance: Chronic wounds are a major burden to patients and to healthcare systems worldwide. These wounds are difficult to heal and treatment is often lengthy and expensive. This has led to research efforts focussed on the wound environment attempting to understand the underlying pathological mechanisms of impaired wound healing. While some of this research has translated to advancements in wound therapies and implementation of new treatment options, chronic wounds remain a significant chall...
3 Citations Source Cite
Published on Jan 1, 2017
Q. Zeng1
Estimated H-index: 1
(SUNY: State University of New York System),
L.K. Macri1
Estimated H-index: 1
(SUNY: State University of New York System)
+ 10 AuthorsDario Stupar2
Estimated H-index: 2
The integration of healing, cell biology, and skin tissue engineering research has been ongoing for nearly one century. In this chapter, we provide a bird’s eye view of skin anatomy and functions, wound healing processes, the challenges and solutions to wound healing. Many techniques and biomaterials have been examined for their potential utility as skin substitutes. Notwithstanding evidence that some strategies have been more successful than others, the ideal skin substitute does not exist. Exi...
Source Cite
Published on Jan 1, 2016
Chronic leg ulcers are a major health problem that affect 1-3% of adults over 65 and are a financial burden on healthcare systems worldwide. In this study biochemical assays were performed on sequential samples collected from both healing and non-healing ulcers. The results demonstrated that inflammatory resolution was necessary for ulcers to heal. Interestingly, in healing ulcers, proteins associated with dampening inflammation did not change over time whilst those keeping the wound in an infla...
Published on Apr 1, 2015in International Wound Journal 2.38
Gary K. Shooter8
Estimated H-index: 8
(QUT: Queensland University of Technology),
Derek R. Van Lonkhuyzen8
Estimated H-index: 8
(QUT: Queensland University of Technology)
+ 6 AuthorsZee Upton31
Estimated H-index: 31
(QUT: Queensland University of Technology)
The majority of the population experience successful wound-healing outcomes; however, 1-3% of those aged over 65 years experience delayed wound healing and wound perpetuation. These hard-to-heal wounds contain degraded and dysfunctional extracellular matrix (ECM); yet, the integrity of this structure is critical in the processes of normal wound healing. Here, we evaluated a novel synthetic matrix protein for its ability to act as an acellular scaffold that could replace dysfunctional ECM. In thi...
4 Citations Source Cite
Published on Jan 1, 2015
Gary K. Shooter8
Estimated H-index: 8
,
Tristan I. Croll14
Estimated H-index: 14
+ 6 AuthorsZee Upton31
Estimated H-index: 31
Dermal wound healing is a biochemical and cellular process critical to life. While the majority of the population will only ever experience successful wound healing outcomes, some 1-3 % of those aged over 65 years will experience wound healing delay or perpetuation. These hard-to-heal wounds are comprised of degraded and dysfunctional extracellular matrix, yet the integrity of this structure is critical in the processes of normal wound healing. As such, extracellular matrix replacements have bee...
Published on Jan 1, 2012
Daniel Broszczak4
Estimated H-index: 4
,
Dario Stupar2
Estimated H-index: 2
+ 5 AuthorsMelissa Laura Fernandez4
Estimated H-index: 4
The lack of fundamental knowledge on the biological processes associated with wound healing represents a significant challenge. Understanding the biochemical changes that occur within a chronic wound could provide insights into the wound environment and enable more effective wound management. We report on the stability of wound fluid samples under various conditions and describe a high-throughput approach to investigate the altered biochemical state within wound samples collected from various ty...
6 Citations
Published on Jan 1, 2012
Dario Stupar2
Estimated H-index: 2
,
Tony J. Parker6
Estimated H-index: 6
+ 2 AuthorsMelissa L. Fernandez1
Estimated H-index: 1
1