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Shayan Sharif
Ontario Veterinary College
165Publications
35H-index
4,511Citations
Publications 165
Newest
Published on Feb 8, 2019in BMC Microbiology 3.29
Mohamed Sarjoon Abdul-Cader4
Estimated H-index: 4
(U of C: University of Calgary),
Upasama De Silva Senapathi1
Estimated H-index: 1
(U of C: University of Calgary)
+ 2 AuthorsMohamed Faizal Abdul-Careem22
Estimated H-index: 22
(U of C: University of Calgary)
Background Single stranded ribonucleic acid (ssRNA) binds to toll-like receptor (TLR)7 leading to recruitment of immune cells and production of pro-inflammatory cytokines, which has been shown in mammals. In chickens, synthetic ssRNA analog, resiquimod, has been shown to elicit antiviral response against infectious bursal disease virus infection. The objective of this study was to determine the innate host responses activated by the pre-hatch in ovo administration of resiquimod against infectiou...
Published on Jul 1, 2019in Trends in Food Science and Technology 8.52
Jake Astill (U of G: University of Guelph), Rozita Dara8
Estimated H-index: 8
(U of G: University of Guelph)
+ 4 AuthorsRickey Y. Yada32
Estimated H-index: 32
(UBC: University of British Columbia)
Abstract Background Modern food supply chains are complex and contain numerous stakeholders, with each performing specific roles pertaining to food production. As food supply chains become more complex, the importance of food production transparency increases. Several factors contribute to the need for transparency such as an increase in the global population, detection of foodborne illness outbreaks, efficient management of risks and recalls, and satisfying consumer demand. A case in point is t...
Published on Jun 1, 2019in Virology 2.66
Neda Barjesteh10
Estimated H-index: 10
(Ontario Veterinary College),
Khaled Taha-Abdelaziz5
Estimated H-index: 5
(Ontario Veterinary College)
+ 1 AuthorsShayan Sharif35
Estimated H-index: 35
(Ontario Veterinary College)
Abstract The chicken upper respiratory tract is the portal of entry for respiratory pathogens including avian influenza virus (AIV). There is a paucity of information about the role of airway epithelial cells in the induction of antiviral responses in the chicken trachea. A better understanding of the role of these cells in the initiation of innate responses may improve prophylactic or therapeutic strategies for control of viral infections. The present study aimed to characterize antiviral innat...
Published in Journal of Dairy Science 3.08
Mehdi Emam2
Estimated H-index: 2
(Ontario Veterinary College),
Saeid Tabatabaei (Ontario Veterinary College)+ -3 AuthorsB.A. Mallard31
Estimated H-index: 31
(Ontario Veterinary College)
ABSTRACT The dynamic interaction between the host and pathogens, along with environmental factors, influences the regulation of mammalian immune responses. Therefore, comprehensive in vivo immune-phenotyping during an active response to a pathogen can be complex and prone to confounding effects. Evaluating critical fundamental aspects of the immune system at a cellular level is an alternative approach to reduce this complexity. Therefore, the objective of the current study was to examine an in v...
Published on Jul 10, 2019in Viruses 3.81
Gabriela Beltrán1
Estimated H-index: 1
,
David J. Hurley1
Estimated H-index: 1
+ 6 AuthorsMaricarmen García28
Estimated H-index: 28
Infectious laryngotracheitis (ILT) is an acute respiratory disease of poultry caused by infectious laryngotracheitis virus (ILTV). Control of the disease with live attenuated vaccines administered via eye drop build upon immune responses generated by the eye-associated lymphoid tissues. The aim of this study was to assess cytokine and lymphocyte changes in the conjunctiva-associated lymphoid tissues (CALT) and Harderian gland (HG) stimulated by the ocular inoculation of the ILTV chicken embryo o...
Published on May 7, 2019in Avian Pathology 1.96
Tamiru Negash Alkie6
Estimated H-index: 6
(Ontario Veterinary College),
Alexander Yitbarek7
Estimated H-index: 7
(Ontario Veterinary College)
+ 3 AuthorsShayan Sharif35
Estimated H-index: 35
(Ontario Veterinary College)
Newly hatched chickens are confronted by a wide array of pathogenic microbes because their adaptive immune defences have limited capabilities to control these pathogens. In such circumstances, and within this age group, innate responses provide a degree of protection. Moreover, as the adaptive immune system is relatively naive to foreign antigens, synergy with innate defences is critical. This review presents knowledge on the ontogeny of innate immunity in chickens pre-hatch and early post-hatch...
Published on Jul 1, 2019in Veterinary Microbiology 2.79
Laura L. Bassel2
Estimated H-index: 2
,
Emily I. Kaufman + 7 AuthorsJeff L. Caswell23
Estimated H-index: 23
Mannheimia haemolytica is an important cause of bovine respiratory disease (BRD). BRD is usually a multifactorial disease with host factors and viral infections influencing pathogenesis. Previous studies that have attempted to experimentally induce pneumonia using aerosolized M. haemolytica alone have produced inconsistent results, yet an aerosol model would be useful to study the details of early infection and to investigate the role of innate defences in pathogenesis. The objective of these st...
Published on Feb 1, 2019in Anaerobe 2.70
A. Najarian1
Estimated H-index: 1
(U of G: University of Guelph),
Shayan Sharif35
Estimated H-index: 35
(U of G: University of Guelph),
Mansel W. Griffiths53
Estimated H-index: 53
(U of G: University of Guelph)
Abstract Clostridium difficile infection is a range of toxin - mediated intestinal diseases that is often acquired in hospitals and small communities in developed countries. The main virulence factors of C. difficile are two exotoxins, toxin A and toxin B, which damage epithelial cells and manifest as colonic inflammation and mild to severe diarrhea. Inhibiting C. difficile adherence, colonization, and reducing its toxin production could substantially minimize its pathogenicity and lead to faste...
Published on Jan 1, 2019in Veterinary Immunology and Immunopathology 1.85
Bahram Shojadoost3
Estimated H-index: 3
(Ontario Veterinary College),
Raveendra R. Kulkarni13
Estimated H-index: 13
(Ontario Veterinary College)
+ 7 AuthorsShayan Sharif35
Estimated H-index: 35
(Ontario Veterinary College)
Abstract Selenium supplementation in poultry feeds has been known to have beneficial effects on the bird health and performance; however antiviral effects of selenium have remained largely unknown. In this study, we have evaluated the effects of supplementation of chicken diets with organic (Selenium Enriched Yeast; SEY) and inorganic selenium (Sodium Selenite; SS) on low pathogenicity avian influenza virus (H9N2) shedding in the cloacal and oropharyngeal swab samples as well as examined the exp...
Published on Dec 1, 2018in Scientific Reports 4.01
Alexander Yitbarek7
Estimated H-index: 7
(U of G: University of Guelph),
Khaled Taha-Abdelaziz5
Estimated H-index: 5
(U of G: University of Guelph)
+ 6 AuthorsShayan Sharif35
Estimated H-index: 35
(U of G: University of Guelph)
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