Gösta B. Pettersson
Cleveland Clinic
SurgeryCardiologyInfective endocarditisLung transplantationMedicine
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Publications 375
#1Daniel R. Martin (Cleveland Clinic Lerner Research Institute)
#2James Witten (Cleveland Clinic)H-Index: 1
Last. Suneel S. Apte (Cleveland Clinic Lerner Research Institute)H-Index: 11
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Infective endocarditis is a life-threatening infection of heart valves and adjacent structures characterized by vegetations on valves and other endocardial surfaces, with tissue destruction and risk of embolization. We used high-resolution mass spectrometry to define the proteome of staphylococcal and non-staphylococcal vegetations and Terminal Amine Isotopic Labeling of Substrates (TAILS) to define their proteolytic landscapes. These approaches identified over 2000 human proteins in staphylococ...
#1Nicolas Isaza (Cleveland Clinic)
#2Nabin K. Shrestha (Cleveland Clinic)H-Index: 18
Last. Bo Xu (Cleveland Clinic)H-Index: 4
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Background Limited data exist regarding the clinical characteristics and contemporary outcomes of patients with pulmonary valve (PoV) infective endocarditis (IE). Methods This is a retrospective cohort study of patients with a confirmed diagnosis of IE affecting the PoV at our centre between January 2002 and October 2018. Electronic medical records were reviewed to gather the clinical and echocardiographic variables. The population was subdivided according to risk factor profiles: group 1: misce...
#1Nabin K. Shrestha (SHM: Society of Hospital Medicine)H-Index: 1
#1Nabin K. Shrestha (Cleveland Clinic)H-Index: 18
Last. Steven M. Gordon (SHM: Society of Hospital Medicine)H-Index: 1
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Abstract Background Prosthetic valve endocarditis (PVE) is a serious condition with high morbidity and mortality. This study investigated the association of surgical treatment with survival among patients with PVE. Methods A retrospective cohort study was done of patients with PVE hospitalized over 8 years in a large referral center. Association of surgery with survival was evaluated using multivariable Cox proportional hazards regression, adjusting for propensity to be accepted for surgery, and...
2 CitationsSource
Abstract Splenic abscess is an uncommon but serious complication of infective endocarditis (IE). The timing of surgical management of splenic abscess can be challenging when valve surgery is required. The American Heart Association (AHA) and the European Society of Cardiology (ESC) currently recommends splenectomy before valve replacement due to fear of reinfection of the heart valve; however, published data to support this recommendation are limited. In this series, we report outcomes for 5 pat...
Last. Nimit Singhal (Royal Adelaide Hospital)H-Index: 14
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Abstract Cardiac angiosarcomas are a rare group of soft tissue sarcomas, characterized by aggressive local growth and early spread. Because this is an uncommon disease, there is currently no standard treatment approach. When localized, surgery appears to lead to the best outcomes, but this can be technically challenging and not always feasible. Upfront chemoradiotherapy provides an alternative that may shrink the tumor to enable definitive surgical resection. We report a case of primary cardiac ...
#1Shirin Siddiqi (Cleveland Clinic)H-Index: 1
#2Kirthi Ravichandren (Cleveland Clinic)H-Index: 3
Last. Penny L. Houghtaling (Cleveland Clinic)H-Index: 38
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Abstract Background Little is known about graft patency after coronary artery bypass grafting (CABG) performed in patients on dialysis. Our aim was to assess patency of internal thoracic artery (ITA) grafts and saphenous vein grafts (SVGs) in these patients. Methods From 1/1997 to 1/2018, 500 patients on dialysis underwent primary CABG with or without concomitant procedures at Cleveland Clinic, 40 of whom had 48 postoperative angiograms for recurrent ischemic symptoms. Complete follow-up was obt...
Abstract Objective The study objective was to determine whether adding prophylactic aorta replacement increases the risk of a cardiac operation when cardiac rather than aortic disease is the primary indication for operation. Methods Patients undergoing cardiac operations with aorta replacement (cardioaortic group), with or without circulatory arrest, were propensity matched to identify patients whose combined operation was not primarily indicated by aortic disease (n = 684). These patients were ...
2 CitationsSource
#1Hani K. Najm (Cleveland Clinic)H-Index: 7
#2Munir Ahmad (Cleveland Clinic)
Last. Tara Karamlou (Cleveland Clinic)H-Index: 37
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Abstract Background Repair of anomalous pulmonary venous return (APVR) when veins are remote from the left atrium (LA) is challenging, and may eventuate in a higher prevalence of pulmonary vein stenosis, superior vena cava (SVC) stenosis, or intracardiac baffle obstruction. We describe our experience in 6 patients with a technique, utilizing both anterior and posterior in-situ pericardial roll repairs, that reduce these complications. Methods Six patients underwent in-situ pericardial roll repai...
#1Kathryn A. Stackhouse (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 4
#2Brian W. McCrindleH-Index: 88
Last. Gösta B. Pettersson (Cleveland Clinic)H-Index: 42
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Abstract Objectives To describe surgical pathway progression through adolescence of an inception cohort of neonates with aortic valve atresia managed initially with either surgical palliation or primary transplantation, comparing survival and self-reported health-related quality of life. Methods From 1994–2000, 565 neonates with aortic atresia were admitted to 26 Congenital Heart Surgeons’ Society hospitals and followed annually for vital status. Initial management included surgical palliation (...
1 CitationsSource
#1Asha Singh (Cleveland Clinic)H-Index: 3
#2Xiaojie Huang (Cleveland Clinic)H-Index: 1
Last. Andra E. Duncan (Cleveland Clinic)H-Index: 10
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Abstract Objectives Long-axis right ventricular (RV) function, which provides nearly 80% of RV ejection, acutely decreases during cardiac surgery. RV dysfunction increases risk for perioperative morbidity and mortality. Our objective was to characterize the change in perioperative RV long-axis and global function by determining the influence of procedure type, surgical approach, and reoperative status and examining its temporal relationship to pericardiotomy versus cardiopulmonary bypass (CPB) a...
6 CitationsSource