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Heiko Schuster
University of Tübingen
42Publications
12H-index
395Citations
Publications 42
Newest
2018 in Nucleic Acids ResearchIF: 11.56
Wenguang Shao2
Estimated H-index: 2
(ETH Zurich),
Patrick G. A. Pedrioli22
Estimated H-index: 22
(ETH Zurich)
+ 43 AuthorsFabio Marino10
Estimated H-index: 10
(Utrecht University)
Mass spectrometry (MS)-based immunopeptidomics investigates the repertoire of peptides presented at the cell surface by major histocompatibility complex (MHC) molecules. The broad clinical relevance of MHC-associated peptides, e.g. in precision medicine, provides a strong rationale for the large-scale generation of immunopeptidomic datasets and recent developments in MS-based peptide analysis technologies now support the generation of the required data. Importantly, the availability of diverse i...
17 Citations Download PDF Cite
2018 in Cancer ResearchIF: 9.13
Markus W. Löffler8
Estimated H-index: 8
(University of Tübingen),
Daniel J. Kowalewski9
Estimated H-index: 9
(University of Tübingen)
+ 15 AuthorsStefan Beckert16
Estimated H-index: 16
Immune cell infiltrates have proven highly relevant for colorectal carcinoma prognosis, making colorectal cancer a promising candidate for immunotherapy. Because tumors interact with the immune system via HLA-presented peptide ligands, exact knowledge of the peptidome constitution is fundamental for understanding this relationship. Here, we comprehensively describe the naturally presented HLA ligandome of colorectal carcinoma and corresponding nonmalignant colon (NMC) tissue. Mass spectrometry i...
2 Citations Source Cite
2018 in ProteomicsIF: 3.53
Jens Fritsche8
Estimated H-index: 8
,
Barbara Rakitsch1
Estimated H-index: 1
+ 14 AuthorsArun Satelli14
Estimated H-index: 14
3 Citations Source Cite
2018 in Scientific DataIF: 5.31
Heiko Schuster12
Estimated H-index: 12
,
Wenguang Shao2
Estimated H-index: 2
+ 10 AuthorsOliver Planz34
Estimated H-index: 34
Download PDF Cite
2018
S Braun , A Marcu (University of Tübingen)+ 9 AuthorsHans-Georg Rammensee82
Estimated H-index: 82
(University of Tübingen)
Source Cite
2018 in BloodIF: 15.13
Tatjana Bilich1
Estimated H-index: 1
,
Annika Nelde2
Estimated H-index: 2
+ 22 AuthorsMarian Christoph Neidert2
Estimated H-index: 2
Source Cite
2017 in Journal of ImmunologyIF: 4.54
Moreno Di Marco4
Estimated H-index: 4
(University of Tübingen),
Heiko Schuster12
Estimated H-index: 12
(University of Tübingen)
+ 3 AuthorsStefan Stevanovic69
Estimated H-index: 69
(University of Tübingen)
The classical HLA-C and the nonclassical HLA-E and HLA-G molecules play important roles both in the innate and adaptive immune system. Starting already during embryogenesis and continuing throughout our lives, these three Ags exert major functions in immune tolerance, defense against infections, and anticancer immune responses. Despite these important roles, identification and characterization of the peptides presented by these molecules has been lacking behind the more abundant HLA-A and HLA-B ...
14 Citations Source Cite
Heiko Schuster12
Estimated H-index: 12
(University of Tübingen),
Janet Kerstin Peper6
Estimated H-index: 6
(University of Tübingen)
+ 21 AuthorsNico Trautwein6
Estimated H-index: 6
(University of Tübingen)
Abstract Immunotherapies, particularly checkpoint inhibitors, have set off a revolution in cancer therapy by releasing the power of the immune system. However, only little is known about the antigens that are essentially presented on cancer cells, capable of exposing them to immune cells. Large-scale HLA ligandome analysis has enabled us to exhaustively characterize the immunopeptidomic landscape of epithelial ovarian cancers (EOCs). Additional comparative profiling with the immunopeptidome of a...
14 Citations Download PDF Cite
Markus W. Löffler8
Estimated H-index: 8
(University of Tübingen),
Heiko Schuster12
Estimated H-index: 12
(University of Tübingen)
+ 10 AuthorsHans-Georg Rammensee82
Estimated H-index: 82
(University of Tübingen)
Background Hyperthermic intraperitoneal chemotherapy (HIPEC) is used to treat peritoneal surface malignancies with application of cytostatic drugs such as oxaliplatin (OX) after cytoreductive surgery. Despite its increased use, evidence for optimal drug dosage, and notably duration of HIPEC, is scarce.
2 Citations Source Cite
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