Match!
Chien Yi Ho
China Medical University (PRC)
21Publications
9H-index
258Citations
Publications 21
Newest
Although dual EGFR/HER2 tyrosine kinase inhibitor lapatinib has provided effective clinical benefits for HER2-positive breast cancer patients, acquired resistance to this drug remains a major concern. Thus, the development of alternative therapeutic strategies is urgently needed for patients who failed lapatinib treatment. Proteasome inhibitors have been reported to possess high anti-tumor activity to breast cancer cells. Therefore, this study aims to examine whether and how proteasome inhibitor...
#1Kuan-Yu Lin (PRC: China Medical University (PRC))
#2Tzu-Ching Shih (PRC: China Medical University (PRC))H-Index: 16
Last.Chien Yi Ho (PRC: China Medical University (PRC))H-Index: 9
view all 6 authors...
The purpose of this study is to use the coronary computed tomography angiography (CCTA) to simulate the coronary blood flow with different theoretical flow models by using not only the computation fluid dynamics (CFD) method, but also additional patient boundary conditions obtained with echocardiography, and evaluate the feasibility of simulated fractional flow reserve (FFRCTS), compared with the invasive CTA-based FFR. The laminar and three turbulence models (k-e(k-epsilon), k-ω(k-omega), SST (...
#1Chung Hsuan Hu (Anhui Medical University)H-Index: 1
#2Chun-Hsu Yao (PRC: China Medical University (PRC))H-Index: 23
Last.Chien Yi Ho (PRC: China Medical University (PRC))H-Index: 9
view all 7 authors...
The incidence of osteoporosis has increased among the elderly population. Establishing a model of bone remodeling for screening new drugs is critical to identify safe and effective treatments for osteoporosis. In this study, we established a platform to investigate the therapeutic effects of collagenous peptides extracted from scales of two kinds of fish, namely, sparidae and chanos. These peptides were prepared using seven concentrations of collagenous peptide: 100, 80, 60, 40, 20, 10 and 1 mg/...
#1Wen Shu Chen (NTU: National Taiwan University)H-Index: 7
#2Liang Chih LiuH-Index: 9
Last.Wei Chien HuangH-Index: 20
view all 9 authors...
// Wen-Shu Chen 1, 2, 5 , Liang-Chih Liu 3, 6 , Chia-Jui Yen 8 , Yun-Ju Chen 9, 10 , Jhen-Yu Chen 2, 5, 7 , Chien-Yi Ho 4 , Shu-Hui Liu 11 , Ching-Chow Chen 1 , Wei-Chien Huang 2, 5, 7, 12 1 Department of Pharmacology, National Taiwan University, Taipei, Taiwan 2 Center for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan 3 Division of Breast Surgery, Department of Surgery, China Medical University Hospital, Taichung, Taiwan 4 Department of Family Medicine, China Medical U...
#1Wen Shu Chen (NTU: National Taiwan University)H-Index: 7
#2C-J Yen (NCKU: National Cheng Kung University)H-Index: 23
Last.Hsiao Lin Pan (ISU: I-Shou University)H-Index: 3
view all 14 authors...
// Wen-Shu Chen 1, 2, 4, * , Chia-Jui Yen 6, * , Yun-Ju Chen 7, 8 , Jhen-Yu Chen 2, 4, 5 , Li-Yun Wang 2, 4 , Shu-Jun Chiu 9, 10 , Wen-Ling Shih 11 , Chien-Yi Ho 3 , Tzu-Tang Wei 1 , Hsiao-Lin Pan 7 , Pei-Hsuan Chien 7 , Mien-Chie Hung 2, 4, 12 , Ching-Chow Chen 1 , Wei-Chien Huang 2, 4, 5, 13 1 Department of Pharmacology, National Taiwan University, Taipei, Taiwan 2 Center for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan 3 Department of Family Medicine, China Medical ...
Acupuncture and electroacupuncture treatments of symptomatic carpal tunnel syndrome (CTS) may improve symptoms and aid nerve repair as well as improve sensory and motor functions. However, limited evidence is available regarding the effects of these treatments based on comprehensive evaluation methods. This research completed the treatment and evaluation of 26 patients with confirmed CTS. Participants were divided into two treatment groups based on a modified neurophysiological grading scale. Of...
#1Chao Ming Hung (ISU: I-Shou University)H-Index: 3
#2Wei Chien HuangH-Index: 20
Last.Wen Shu Chen (PRC: China Medical University (PRC))H-Index: 7
view all 14 authors...
Hepatitis B virus- (HBV-) associated hepatocellular carcinoma (HCC) is the most common type of liver cancer. However, the underlying mechanism of HCC tumorigenesis is very complicated and HBV-encoded X protein (HBx) has been reported to play the most important role in this process. Activation of downstream signal pathways of epidermal growth factor receptor (EGFR) family is known to mediate HBx-dependent HCC tumor progression. Interestingly, HER2 (also known as ErbB2/Neu/EGFR2) is frequently ove...
#1Chia Wen Tsai (PRC: China Medical University (PRC))H-Index: 17
#2Chien Yi Ho (PRC: China Medical University (PRC))H-Index: 9
Last.Hao Ai Shui (NDMC: National Defense Medical Center)H-Index: 3
view all 13 authors...
This study has two aims: [1] to evaluate the association between hOGG1 genotypic polymorphism and endometriosis risk, and [2] to investigate the joint effects of hOGG1 genotype and smoking habit on endometriosis susceptibility in Taiwan. For this purpose, the well-known polymorphic variants of hOGG1, codon 326, was genotyped and analyzed of its association with the risk of endometriosis. In total, 153 patients with endometriosis and 636 non-endometriosis healthy controls were recruited and genot...
#1Chien Yi Ho (PRC: China Medical University (PRC))H-Index: 9
#2Yung-Hsiang Chen (PRC: China Medical University (PRC))H-Index: 35
Last.Yuan Ju Lee (NTU: National Taiwan University)H-Index: 4
view all 11 authors...
Abstract Diet modification plays an important role in nephrolithiasis. Development of an easy, ready-to-use beverage such as a commercial juice drink to use as a preventive treatment for renal calculi formation would be widely welcomed. We previously developed a novel Drosophila model for the study of nephrolithiasis. It provides a new well-established drug discovery platform for this common disease. In our current study, we used the Drosophila model to investigate the preventive effects of vari...
123