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Zhao Zhuo
Zhejiang University
ChemistryFerrousDMT1DuodenumBiochemistry
9Publications
6H-index
65Citations
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Publications 9
Newest
#1Zhao Zhuo (ZJU: Zhejiang University)H-Index: 6
#2Xiaonan Yu (ZJU: Zhejiang University)H-Index: 2
Last. Jie Feng (ZJU: Zhejiang University)H-Index: 11
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This experiment was conducted to evaluate the effects of heme and non-heme iron sources on growth performances, blood parameters, tissue mineral concentration, and intestinal morphology in weanling pigs. At 25 days of age, 32 newly weaned piglets (Duroc × Landrace × Yorkshire; 8.66 ± 0.59 kg) were allocated to one of the following dietary treatments: control group (basal diet with no extra iron addition), FeSO4 group (basal diet + 100 mg Fe/kg as FeSO4), Fe-Gly group (basal diet + 100 mg Fe/kg a...
2 CitationsSource
#1Shenglin Fang (ZJU: Zhejiang University)H-Index: 7
#2Zhao Zhuo (ZJU: Zhejiang University)H-Index: 6
Last. Jie Feng (ZJU: Zhejiang University)H-Index: 11
view all 5 authors...
Abstract The aim of this study was to determine the toxicological effects of excess iron in a liquid iron preparation (especially on intestinal barrier function) and the possible etiology of side effects or diseases caused by the excess iron. In study 1, forty male Sprague-Dawley rats (4–5 wk old) were subjected to oral gavage with 1 ml vehicle (0.01 mol/L HCl) or 1 ml liquid iron preparation containing 8 mg, 16 mg or 24 mg of iron for 30 d. Iron status, oxidative stress, histology (HE tight jun...
8 CitationsSource
#1Qiaoling Hu (ZJU: Zhejiang University)H-Index: 22
#1Qiaoling Hu (ZJU: Zhejiang University)H-Index: 1
Last. Jie Feng (ZJU: Zhejiang University)H-Index: 4
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Plant extracts have been used widely to improve growth, lower cholesterol, and exert antioxidative defense and antimicrobial activities in animal production. The present study aimed to investigate the effects of dietary phytosterols (PS) on growth performance, antioxidant enzymes and intestinal morphology in weaned piglets.; Results: A total of 120 crossbred piglets, weighing 9.58 ± 0.26 kg, were randomly allocated to three treatments: control, PS (0.2 g kg-1 ) and polymyxin E (0.04 g kg-1 , ant...
7 CitationsSource
#1Qiaoling Hu (ZJU: Zhejiang University)H-Index: 22
#1Qiaoling Hu (ZJU: Zhejiang University)H-Index: 2
Last. Jie Feng (ZJU: Zhejiang University)H-Index: 4
view all 5 authors...
Phytosterols (PS), plant-derived natural steroid compounds, are novel feed additives to regulate immune function and promote pig growth. This study was conducted to determine the effects of PS on the immune response of weaned piglets.; Results: One hundred and twenty crossbred (Duroc × Landrace × Yorkshire) piglets with an average initial weight of 9.58 ± 0.26 kg were randomly allotted to three treatments. Treatments consisted of a control, PS (0.2 g kg-1 ) and polymyxin E (0.04 g kg-1 , antibio...
11 CitationsSource
#1Zhao ZhuoH-Index: 6
#2Shenglin FangH-Index: 7
Last. Jie FengH-Index: 4
view all 5 authors...
Digital gene expression profiling analysis of duodenum transcriptomes in SD rats administered ferrous sulfate or ferrous glycine chelate by gavage
6 CitationsSource
#1Danping Huang (ZJU: Zhejiang University)H-Index: 1
#2Zhao Zhuo (ZJU: Zhejiang University)H-Index: 6
Last. Jie Feng (ZJU: Zhejiang University)H-Index: 4
view all 5 authors...
This study was conducted to investigate the effects of zinc sources on gene expression of zinc-related transporters in intestinal porcine epithelial cells (IPEC-1). IPEC-1 cells were treated with zinc glycine chelate (Zn-Gly), zinc methionine (Zn-Met), and zinc sulfate (ZnSO4), respectively, for measurement of cell viability. Then, the relative expression of zinc-related transporters in IPEC-1 in response to different zinc sources (50 μmol/L zinc) was measured. Zinc transporter SLC39A4 (ZIP4) ex...
8 CitationsSource
#1Min Yue (ZJU: Zhejiang University)H-Index: 4
#2Shenglin Fang (ZJU: Zhejiang University)H-Index: 7
Last. J. Feng (ZJU: Zhejiang University)H-Index: 14
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Summary This study was conducted to investigate absorption characteristics of zinc glycine chelate (Zn–Gly) by evaluating tissues zinc status and the expression of zinc transporters in rats. A total of 24 male rats were randomly allocated to three treatments and administered either saline or 35 mg Zn/kg body weight from zinc sulphate (ZnSO4) or Zn–Gly by feeding tube separately. Four rats per group were slaughtered and tissues were collected at 2 and 6 h after gavage respectively. Our data showe...
6 CitationsSource
#1Zhao Zhuo (ZJU: Zhejiang University)H-Index: 6
#2Shenglin Fang (ZJU: Zhejiang University)H-Index: 7
Last. Jie Feng (ZJU: Zhejiang University)H-Index: 4
view all 5 authors...
Ferrous glycinate (Fe-Gly) maintains high bioavailability in animals, but its exact absorption mechanism is still unknown. Here, we studied on the absorption kinetics of ferrous glycinate and its impact on the relevant transport protein in Sprague-Dawley (SD) rats. A total of 72 SD rats (male, BW 100 ± 6.25 g) were randomly allotted to three treatments. These treatments were perfused with 1 mL of normal saline, ferrous sulfate (FeSO4), and ferrous glycinate (71.35 mg/L as iron) separately. Four ...
10 CitationsSource
#1C.L. Fang (ZJU: Zhejiang University)H-Index: 1
#2Zhao Zhuo (ZJU: Zhejiang University)H-Index: 6
Last. J. Feng (ZJU: Zhejiang University)H-Index: 14
view all 5 authors...
Abstract The study was conducted to compare the effects of ferrous sulfate (FeSO 4 ) and iron glycine chelate (Fe-Gly) on iron status and gene expression of iron related transporters in iron-deficient piglets. Eighteen piglets (Duroc × Landrace × Yorkshire; 6.50 ± 0.52 kg) were selected to conduct the study. In period 1, all pigs were fed an iron-deficient diet (basal diet; 20.23 mg Fe/kg of diet) for 19 days until iron-deficient anemia was induced. In period 2, the eighteen piglets were randoml...
7 CitationsSource
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