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Iram Gull
University of the Punjab
16Publications
5H-index
110Citations
Publications 16
Newest
#1Iram Gull (University of the Punjab)H-Index: 5
#2Muhammad Shahbaz Aslam (University of the Punjab)H-Index: 5
Last.Muhammad Amin Athar (University of the Punjab)H-Index: 10
view all 6 authors...
Interferon therapy for the treatment of hepatitis C virus infection has very limited clinical application due to short serum half-life and side effects of therapy in systemic route of administration. In the present study, we have focused to improve the interferon therapy by overcoming the limitation of side effects. We hypothesized that latent interferon alpha 2b (IFNα2b) produced by fusion of Latency associated protein (LAP) domain of TGFβ and IFNα2b having HCV NS3 protease cleavage site as lin...
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The worldwide high mortality rate of lung cancer could be reduced significantly by its noninvasive early detection. The quantitative analysis of cell-free circulating DNA in plasma presents a potential noninvasive approach for liquid biopsy of tumor. In this study, real-time polymerase chain reaction–based approach was used to quantify free circulating DNA in plasma. The concentration of free circulating DNA was checked using human telomerase reverse transcriptase gene as marker, and amplificati...
1 CitationsSource
#1Iram GullH-Index: 5
#2Attia JavedH-Index: 1
Last.Muhammad Amin AtharH-Index: 10
view all 5 authors...
The use of Moringa oleifera as natural food preservative has been evaluated in the present study. In addition, for quality assurance, the study has also been focused on the shelf life of product to authenticate the identification of plant by development of DNA based marker. Among the different extracts prepared from flower pods of Moringa oleifera, methanol and aqueous extract exhibited high antibacterial and antioxidant activity, respectively. The high phenolic contents (53.5 ± 0.169 mg GAE/g) ...
1 CitationsSource
#1Muhammad Shahbaz Aslam (University of the Punjab)H-Index: 5
#2T. Khalid (University of the Punjab)H-Index: 1
Last.Muhammad Amin Athar (University of the Punjab)H-Index: 10
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The pollen of Paper Mulberry (Broussonetia papyrifera) is a major cause of urticaria and severe respiratory symptoms. The composition of allergens of Paper Mulberry pollen has not yet been determined. In the present study, we identified and characterised the potential allergens in Paper Mulberry pollen involved to trigger the allergic reaction in humans and also purified 40 kDa allergen protein of Paper Mulberry. Pollen was collected from Paper Mulberry trees planted in Islamabad. Soluble protei...
1 Citations
#2T. KhalidH-Index: 1
Last.Muhammad Amin AtharH-Index: 10
view all 5 authors...
The pollen of Paper Mulberry (Broussonetia papyrifera) is a major cause of urticaria and severe respiratory symptoms. The composition of allergens of Paper Mulberry pollen has not yet been determined. In the present study, we identified and characterised the potential allergens in Paper Mulberry pollen involved to trigger the allergic reaction in humans and also purified 40 kDa allergen protein of Paper Mulberry. Pollen was collected from Paper Mulberry trees planted in Islamabad. Soluble protei...
#1Muhammad Shahbaz Aslam (University of the Punjab)H-Index: 5
#2Sidra NaveedH-Index: 2
Last.Muhammad Amin AtharH-Index: 10
view all 6 authors...
Side-effects associated with the cancer chemotherapy limit the scope of chemotherapeutic drugs and no data was available about these side effects in Pakistan. Moreover starvation based differential chemotherapy has been proved to greatly reduce the side effects of chemotherapy depending on starvation time. The current study was conducted to survey the common side effects of the chemotherapeutic drugs and the role of starvation to reduce them. The study included total 100 subjects with multiple c...
19 CitationsSource
#1Iram Gull (University of the Punjab)H-Index: 5
#2Zahoor Qadir Samra (University of the Punjab)H-Index: 8
Last.Muhammad Amin Athar (University of the Punjab)H-Index: 10
view all 4 authors...
Interferon alpha 2b (IFNα-2b) is an important cytokine and used for antiviral and anticancer treatment. The low cost production of IFNα-2b with high biological activity is necessary to provide the interferon therapy to the hepatitis patients in Pakistan. In the present study, human interferon alpha 2b (hIFNα-2b) gene from a healthy person was cloned and overexpressed in E. coli BL21(DE3). The molecular weight of the expressed hIFNα-2b is 19 kDa. The over expressed recombinant hIFNα-2b was checke...
6 CitationsSource
The present study was conducted to explore the potential fungal isolates for maximum production of phytase by optimizing solid substrate preference and growth parameters (pH, temperature, fermentation time) of solid state fermentation (SSF). It has been inferred from the results that all the tested fungi (Aspergillus niger, Aspergillus flavus, Aspergillus versicolor, Aspergillus nidulans, Cladosporium cladosporioides, Trichoderma reesei, and Trichoderma viride) showed inducible expression of phy...
3 CitationsSource
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