Mingzhi Zhang
Soochow University (Suzhou)
Prospective cohort studyPopulationStrokeDiabetes mellitusMedicine
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Publications 24
#1Hao Peng (Soochow University (Suzhou))H-Index: 8
#2Jia Yu (Soochow University (Suzhou))
Last. Mingzhi Zhang (Soochow University (Suzhou))H-Index: 5
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BACKGROUND: As a key enzyme of natriuretic peptides system playing an integral role in energy homeostasis, furin may be a potential contributor to obesity. However, the association between furin and obesity has been scarcely studied. This study aims to examine the prospective association between serum furin and abdominal obesity. METHODS: Waist circumference (WC) was measured twice 4 years apart for a total of 892 Chinese adults free of abdominal obesity at baseline. Abdominal obesity was define...
1 CitationsSource
Background. Platelet consumption followed by homocysteine-induced endothelial injury suggests a crosstalk between platelet activation and homocysteine on hypertension. Platelet count has been found to modify the effect of folic acid on vascular health. However, whether platelet count could modify the contribution of homocysteine to blood pressure (BP) remains unclear. Methods. Leveraging a community-based cross-sectional survey in 30,369 Chinese hypertensive patients (mean age 62 years, 52% fema...
#1Ting Ting Wang (Soochow University (Suzhou))H-Index: 1
#2Wanlin Zhang (Soochow University (Suzhou))
Last. Shaoyan Zhang (Soochow University (Suzhou))
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Abstract Aim The study examined the association between resting heart rate and risk of type 2 diabetes (T2D) and cardiovascular events in an Inner Mongolian population. Methods Based on a cross-sectional survey carried out in 2003, 2530 participants were reinvestigated between 2013 and 2014. All participants were classified into four groups (quartiles) according to heart rate. Primary outcomes were hypertension, T2D, major macrovascular events and all-cause deaths. Logistic regression models wer...
#1Huijian Xie (Soochow University (Suzhou))
Last. Mingzhi Zhang (Soochow University (Suzhou))
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Up to date, human urotensin II (UII) is the most potent vasoconstrictor in mammalian animals. To explore whether UII played an important role in the development of hypertension, we conducted a prospective study in Changshu city, China. The baseline investigation was carried out in 2007, and the first follow-up investigation was conducted in 2013. From the participants, we randomly obtained 2000 normotensive subjects aged 40 years and older without any severe disease at baseline and examined plas...
#1Yiting Zhou (Soochow University (Suzhou))H-Index: 1
#2Rui Zhang (Soochow University (Suzhou))
Last. Yonghong Zhang (Soochow University (Suzhou))H-Index: 15
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AbstractObjective: To investigate the coexistence effect of hypertension and angiotensin II on the risk of coronary heart disease based on a prospective study in an Inner Mongolian population of Ch...
#1Yan He (Soochow University (Suzhou))
#2Liyun Ren (Soochow University (Suzhou))
Last. Yonghong Zhang (Soochow University (Suzhou))H-Index: 15
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The cardiovascular protective role of furin has been suggested by some animal-based studies but has not been well studied in humans. Therefore, the objective of this study was to examine the prospective association between serum furin and high blood pressure in a longitudinal cohort of Chinese adults. Leveraging a longitudinal prospective cohort with blood pressure examined twice on average 4 years apart, we systemically examined the cross-sectional, longitudinal, and prospective associations of...
#1Ni Mei Zeng (Soochow University (Suzhou))
#2Xiao Wei Zheng (Soochow University (Suzhou))
Last. Yong Hong Zhang (Soochow University (Suzhou))H-Index: 4
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The objective of this study was to evaluate the usefulness of the China-PAR equations in predicting the 10-year risk of cardiovascular disease (CVD) in the Inner Mongolians population. A population-based, prospective cohort of 2, 589 Mongolians were followed up from 2003 to 2012. Participants were categorized into 4 subgroups according to their 10-year CVD risks calculated using the China-PAR equations: < 5%, 5%-9.9%, 10%-19.9%, and ≥ 20%. The China-PAR equations discriminated well with good C s...
#1Qiao Yan Qiu (Soochow University (Suzhou))H-Index: 2
#2Bei Lei Zhang (Soochow University (Suzhou))H-Index: 1
Last. Shao Yan Zhang (Soochow University (Suzhou))H-Index: 2
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This prospective study was designed to examine the combined influence of insulin resistance (IR) and inflammatory biomarker levels on type 2 diabetes mellitus (T2DM) among 1,903 Inner Mongolians. During follow-up, 205 (10.77%) participants developed T2DM, and the incidence of T2DM was higher among subjects with IR, elevated C-reactive protein (CRP), elevated sICAM-1, elevated sE-selectin, or the coexistences of IR with elevated CRP, elevated sICAM-1, elevated sE-selectin, and elevated angiotensi...
2 CitationsSource
#1Xinfeng Huangfu (Soochow University (Suzhou))H-Index: 2
#2Zhengbao Zhu (Soochow University (Suzhou))H-Index: 2
Last. Yonghong Zhang (Soochow University (Suzhou))H-Index: 15
view all 12 authors...
Objective We intended to investigate the combined effect of smoking and hypertension on ischemic stroke incidence based on a 10-year prospective study among Inner Mongolians in China. Methods A prospective cohort study from June 2003 to July 2012 was conducted among 2589 participants aged 20 years and older from Inner Mongolia, China. We categorized the participants into 4 subgroups according to the status of smoking and hypertension. The cumulative incidence rates of ischemic stroke among the 4...
3 CitationsSource