Dylan B. George
Biomedical Advanced Research and Development Authority
Public healthEcologyPopulationGlobal healthBiology
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Publications 35
#1Matthew Biggerstaff (CDC: Centers for Disease Control and Prevention)H-Index: 26
#2Fredrick Scott Dahlgren (CDC: Centers for Disease Control and Prevention)H-Index: 1
Last. Joseph T. Wu (HKU: University of Hong Kong)H-Index: 36
view all 20 authors...
Health planners from global to local levels must anticipate year‐to‐year and week‐to‐week variation in seasonal influenza activity when planning for and responding to epidemics to mitigate their impact. To help with this, countries routinely collect incidence of mild and severe respiratory illness and virologic data on circulating subtypes and use these data for situational awareness, burden of disease estimates and severity assessments. Advanced analytics and modelling are increasingly used to ...
2 CitationsSource
#1Dylan B. GeorgeH-Index: 20
#2Wendy Taylor (Rockefeller Foundation)H-Index: 1
Last. Nicholas G. Reich (UMass: University of Massachusetts Amherst)H-Index: 24
view all 11 authors...
Forecasting is beginning to be integrated into decision-making processes for infectious disease outbreak response. We discuss how technologies could accelerate the adoption of forecasting among public health practitioners, improve epidemic management, save lives, and reduce the economic impact of outbreaks.
4 CitationsSource
#1Jean-Paul Chretien (Silver Spring Networks)H-Index: 19
#2Steven Riley (Imperial College London)H-Index: 48
Last. Dylan B. George (Biomedical Advanced Research and Development Authority)H-Index: 20
view all 3 authors...
The outbreak of Ebola that started in West Africa in late 2013 has caused at least 28,000 illnesses and 11,000 deaths. As the outbreak progressed, global and local public health authorities scrambled to contain the spread of the disease by isolating those who were ill, putting in place infection control processes in health care settings, and encouraging the public to take steps to prevent the spread of the illness in the community. It took a massive investment of resources and personnel from man...
71 CitationsSource
#1Jean-Paul Chretien (Silver Spring Networks)H-Index: 19
#2Steven Riley (Imperial College London)H-Index: 48
Last. Dylan B. George (Biomedical Advanced Research and Development Authority)H-Index: 20
view all 3 authors...
1 CitationsSource
#1Benjamin M. Althouse (SFI: Santa Fe Institute)H-Index: 27
#2Samuel V. Scarpino (SFI: Santa Fe Institute)H-Index: 21
Last. Amy Wesolowski (Harvard University)H-Index: 22
view all 36 authors...
Novel data streams (NDS), such as web search data or social media updates, hold promise for enhancing the capabilities of public health surveillance. In this paper, we outline a conceptual framework for integrating NDS into current public health surveillance. Our approach focuses on two key questions: What are the opportunities for using NDS and what are the minimal tests of validity and utility that must be applied when using NDS? Identifying these opportunities will necessitate the involvement...
73 CitationsSource
#1Pete RileyH-Index: 28
#2Michal Ben-NunH-Index: 5
Last. Steven Riley (Imperial College London)H-Index: 48
view all 8 authors...
The potential rapid availability of large-scale clinical episode data during the next influenza pandemic suggests an opportunity for increasing the speed with which novel respiratory pathogens can be characterized. Key intervention decisions will be determined by both the transmissibility of the novel strain (measured by the basic reproductive number R 0) and its individual-level severity. The 2009 pandemic illustrated that estimating individual-level severity, as described by the proportion p C...
6 CitationsSource
#1Jane P. Messina (University of Oxford)H-Index: 26
#2David M. Pigott (University of Oxford)H-Index: 7
Last. Simon I. Hay (University of Oxford)H-Index: 121
view all 15 authors...
Background: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne infection caused by a virus (CCHFV) from the Bunyaviridae family. Domestic and wild vertebrates are asymptomatic reservoirs for the virus, putting animal handlers, slaughter-house workers and agricultural labourers at highest risk in endemic areas, with secondary transmission possible through contact with infected blood and other bodily fluids. Human infection is characterized by severe symptoms that often result in death. While ...
93 CitationsSource
#1Gabriel Rainisch (CDC: Centers for Disease Control and Prevention)H-Index: 4
#2Jason Asher (Leidos)H-Index: 7
Last. Martin I. MeltzerH-Index: 42
view all 13 authors...
To the Editor: By December 31, 2014, the Ebola epidemic in West Africa had resulted in treatment of 10 Ebola case-patients in the United States; a maximum of 4 patients received treatment at any one time (1). Four of these 10 persons became clinically ill in the United States (2 infected outside the United States and 2 infected in the United States), and 6 were clinically ill persons medically evacuated from West Africa (Technical Appendix 1 Table 6). To plan for possible future cases in the Uni...
11 CitationsSource
The National Science and Technology Council, within the Executive Office of the President, established the Pandemic Prediction and Forecasting Science and Technology Working Group in 2013 to advance US Government epidemic prediction and forecasting capabilities. Working Group leaders will provide an overview of activities, and seek feedback on the Working Group direction from the ISDS community.
16 CitationsSource
#1Colin A. Russell (University of Cambridge)H-Index: 35
#2Peter M. Kasson (UVA: University of Virginia)H-Index: 20
Last. Jesse D. Bloom (Fred Hutchinson Cancer Research Center)H-Index: 42
view all 28 authors...
Assessing the pandemic risk posed by specific non-human influenza A viruses is an important goal in public health research. As influenza virus genome sequencing becomes cheaper, faster, and more readily available, the ability to predict pandemic potential from sequence data could transform pandemic influenza risk assessment capabilities. However, the complexities of the relationships between virus genotype and phenotype make such predictions extremely difficult. The integration of experimental w...
39 CitationsSource