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Chien-Hsieh Chiang
National Taiwan University
Viral loadHepatitis BHepatitis B virusDiabetes mellitusMedicine
13Publications
8H-index
162Citations
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Publications 13
Newest
This study sought to determine whether chronic hepatitis B or C would modify the association between insulin analogues and hepatocellular carcinoma (HCC) risks. We conducted a nationwide nested case-control study for HCC cases and matched controls from 2003 to 2013 among newly diagnosed type 2 diabetes patients on any antidiabetic agents in Taiwan before and after exclusion of chronic viral hepatitis, respectively. A total of 5832 and 1237 HCC cases were identified before and after exclusion of ...
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#1Chia-Wen LuH-Index: 9
#2Hao-Hsiang ChangH-Index: 9
Last. Kuo-Chin HuangH-Index: 41
view all 6 authors...
Few studies have investigated the association between selenium and metabolic syndrome. This study aimed to explore the associations between the serum selenium level and metabolic syndrome as well as examining each metabolic factor. In this case-control study, the participants were 1165 adults aged ≥40 (65.8 ± 10.0) years. Serum selenium was measured by inductively coupled plasma-mass spectrometry. The associations between serum selenium and metabolic syndrome were examined by multivariate logist...
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#1Chia-Hsuin ChangH-Index: 32
#2Chien-Hsieh ChiangH-Index: 8
Last. Mei-Shu LaiH-Index: 39
view all 6 authors...
The study aimed to investigate the association of long-term use of different antihypertensive agents with incident breast cancer.A total of 794 ,533 women aged at least 55 years were identified from Taiwan National Health Insurance claims database during 2001-2011. As of 31 December 2011, incident breast cancer patients were included as cases, and 1 : 4 age-matched controls were selected by risk-set sampling scheme. Logistic regression models were applied to estimate the odds ratios (ORs) and 95...
5 CitationsSource
#1Chiao-Yu Huang (NTU: National Taiwan University)H-Index: 3
#2Chia-Wen Lu (NTU: National Taiwan University)H-Index: 9
Last. Kuo-Chin Huang (NTU: National Taiwan University)H-Index: 41
view all 6 authors...
Objective Investigate the nature of the relationship between chronic hepatitis B virus (HBV) infection and metabolic syndrome among nondiabetic adults. Methods This was a cross-sectional analysis of 17,030 nondiabetic adults (7437 males and 9593 females; mean age, 36.0 ± 3.9 years) in northern Taiwan from 2008 to 2009. The associations of hepatitis B surface antigen (HBsAg) seropositivity with metabolic syndrome and cardio-metabolic parameters were assessed. A structural equation model was const...
13 CitationsSource
#1Chien-Hsieh ChiangH-Index: 8
#2Chia-Wen LuH-Index: 9
Last. Kuo-Chin HuangH-Index: 41
view all 7 authors...
The relationship of diabetes and smoking status to hepatocellular carcinoma (HCC) mortality is not clear. We aimed to investigate the association of smoking cessation relative to diabetes status with subsequent deaths from HCC. We followed up 51,164 participants (aged 44–94 years) without chronic hepatitis B or C from 1 January 1998 to 31 December 2008 enrolled from nationwide health screening units in a prospective cohort study. The primary outcomes were deaths from HCC. During the study period...
7 CitationsSource
#1Ping-Hsun Chang (NTU: National Taiwan University)H-Index: 1
#2Chien-Hsieh Chiang (NTU: National Taiwan University)H-Index: 8
Last. Fei-Ran Guo (NTU: National Taiwan University)H-Index: 7
view all 6 authors...
Background Smoking is a major preventable cause of morbidity and premature death worldwide. Both varenicline and nicotine replacement therapy (NRT) help achieve smoking cessation. However, limited evidence exists regarding whether combination of varenicline and NRT is more effective than either alone. The aim of this research was to investigate the efficacy and safety of varenicline combined with NRT.
24 CitationsSource
#1Chien-Hsieh Chiang (NTU: National Taiwan University)H-Index: 8
#2Kuo-Chin Huang (NTU: National Taiwan University)H-Index: 41
1 CitationsSource
There are limited data regarding the relationship between chronic hepatitis B virus (HBV) infection and metabolic factors. This article aims to highlight the link of metabolic factors with hepatitis B surface antigen (HBsAg) serostatus, HBV load, and HBV-related hepatocellular carcinoma (HCC). Although HBsAg-positive serostatus was positively correlated with a high risk of metabolic syndrome in students, chronic HBV-infected individuals have high serum adiponectin levels. The androgen pathway in...
13 CitationsSource
#1Chien-Hsieh Chiang (NTU: National Taiwan University)H-Index: 8
#2Long Teng Lee (NTU: National Taiwan University)H-Index: 7
Last. Kuo-Chin Huang (NTU: National Taiwan University)H-Index: 41
view all 8 authors...
Limited data exist regarding metabolic risk factors for deaths from hepatocellular carcinoma (HCC) in aging individuals. We investigated the association between diabetes, dyslipidemia, and HCC mortality in those aged 40 years or more (middle-aged and elderly). In this prospective cohort study based on nationwide health screening units, we consecutively followed middle-aged and elderly participants who had no chronic hepatitis B or C virus infection and received health screening from January 1 19...
20 CitationsSource
#1Chien-Hsieh Chiang (NTU: National Taiwan University)H-Index: 8
#2Hwai I. YangH-Index: 37
Last. Chien-Jen Chen (NTU: National Taiwan University)H-Index: 115
view all 9 authors...
This study aimed to investigate the metabolic risk factors of high hepatitis B viral load. Large-scale, community-based cross-sectional study. A total of 3587 hepatitis B virus (HBV)-infected participants without liver cirrhosis at study entry were investigated. High HBV viral load was defined as a serum level ⩾104 copies per ml for hepatitis B e antigen (HBeAg) seronegatives or ⩾108 copies per ml for HBeAg seropositives. Among HBeAg seropositives (n=545), high HBV viral load was reversely assoc...
22 CitationsSource
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