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Fernando Barbosa
University of São Paulo
258Publications
40H-index
5,409Citations
Publications 258
Newest
#1Romena Sanglard Silveira (USP: University of São Paulo)
#2Bruno Alves Rocha (USP: University of São Paulo)H-Index: 12
Last.Fernando Barbosa (USP: University of São Paulo)H-Index: 40
view all 0 authors...
Abstract A high demand exists in human biomonitoring studies for reliable and straightforward methods that generate data faster and simultaneously. Thus, the present study combines microextraction by packed sorbent (MEPS) and liquid chromatography coupled to mass spectrometry (LC-MS/MS) for simultaneous extraction and determination of various classes of endocrine-disrupting chemicals (EDCs), including parabens, benzophenones, bisphenols, and the antimicrobial, triclocarban in human urine samples...
#1Lara Ferreira Azevedo (USP: University of São Paulo)H-Index: 2
#2Carlos R.P. Dechandt (USP: University of São Paulo)H-Index: 3
Last.Fernando Barbosa (USP: University of São Paulo)H-Index: 40
view all 6 authors...
Abstract The present study evaluates the effects of low-level long-term exposure to bisphenol A (BPA) and bisphenol S (BPS) on serum biochemical markers, glucose homeostasis, mitochondrial energy metabolism, biogenesis and dynamics, and redox status in livers of Wistar rats. While only the exposure to BPS induces a significant body mass gain after 21 weeks, both compounds alter serum lipid levels and lead to the development of glucose intolerance. Regarding mitochondrial metabolism, both bisphen...
#1Maísa Daniela Habenschus (FFCLRP: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto)H-Index: 3
#2Viviani Nardini (FFCLRP: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto)H-Index: 8
Last.Anderson Rodrigo Moraes de Oliveira (FFCLRP: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto)H-Index: 16
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Abstract Tebuconazole (TEB) is a chiral triazole fungicide that is globally marketed and used as a racemic mixture to control plant pathogens. Due to its use as a racemic mixture, TEB may exhibit enantioselective toxicokinetics toward nontarget organisms, including humans. Therefore, the in vitro enantioselective metabolism of TEB by cytochrome P450 enzymes (CYP450) was studied using human liver microsomes, and the in vivo toxicokinetic parameters were predicted. A new enantioselective, reversed...
Abstract The Brazil nut is an excellent source of selenium (Se), an essential micronutrient for human health. In this study, we hypothesized that Brazil nut intake modulates circulating microRNAs (miRNAs) in obese women and aimed to evaluate the effects of this nut intake on circulating miRNAs in women with obesity or metabolic syndrome (MetS). A randomized controlled clinical trial was conducted on 54 subjects recruited from the Clinical Hospital in Sao Paulo, Brazil. Patients were randomly ass...
#1Marília Cristina Oliveira Souza (USP: University of São Paulo)H-Index: 1
#2Bruno Alves Rocha (USP: University of São Paulo)H-Index: 12
Last.Fernando Barbosa (USP: University of São Paulo)H-Index: 40
view all 5 authors...
Polybrominated diphenyl ethers (PBDEs) are a class of flame retardants used in numerous consumer products to increase product resistance to fire and/or high temperatures. However, several studies suggest potential harmful effects on human health after exposure to these compounds. Since diet is a relevant source of PBDE exposure, food samples must be routinely monitored to check for possible contamination. On the other hand, routine food monitoring procedures require fast, simple, sensitive, and ...
#1Bruno Alves Rocha (USP: University of São Paulo)H-Index: 12
#2Silvana Ruella de Oliveira (USP: University of São Paulo)H-Index: 2
Last.Fernando Barbosa (USP: University of São Paulo)H-Index: 40
view all 6 authors...
Abstract A simple and rapid procedure for simultaneous determination of 21 potential endocrine-disrupting chemicals (EDs) in urine samples by liquid chromatography–tandem mass spectrometry (LC–MS/MS) was developed. The novelty of the present procedure is based on the use of low-density solvent air-assisted liquid-liquid microextraction (LDS–AALLME) as a sample preparation step. The target analytes were 7 bisphenols, 7 parabens, 5 benzophenones, and two antimicrobials. The parameters (type and vo...
#1Mariana Lepri de Oliveira (USP: University of São Paulo)
#2Bruno Alves Rocha (USP: University of São Paulo)H-Index: 12
Last.Fernando Barbosa (USP: University of São Paulo)H-Index: 40
view all 4 authors...
Abstract Endocrine-disrupting chemicals are a group of emerging contaminants that alters the function of the endocrine system, causing possible adverse health effects. In this study, a dispersive liquid-liquid microextraction method coupled with liquid chromatography-mass spectrometry for the simultaneous determination of 17 potential EDCs, bisphenols (A, S, P, AP, AF, Z), parabens (methyl-, ethyl-, propyl-, butyl-, benzyl-paraben), benzophenones (3, 1, 2, 8, 4-OH BP) and triclocarban, in human ...
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