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Seth M. Weinberg
University of Pittsburgh
108Publications
24H-index
2,146Citations
Publications 111
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Orofacial clefts (OFCs) are among the most prevalent craniofacial birth defects worldwide and create a significant public health burden. The majority of OFCs are non-syndromic, and the genetic etiology of non-syndromic OFCs is only partially determined. Here, we analyze whole genome sequence (WGS) data for association with risk of OFCs in European and Colombian families selected from a multicenter family-based OFC study. This is the first large-scale WGS study of OFC in parent–offspring trios, a...
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#1Dzemila Sero (Katholieke Universiteit Leuven)H-Index: 1
#2Arslan A Zaidi (PSU: Pennsylvania State University)H-Index: 6
Last.Peter ClaesH-Index: 22
view all 12 authors...
Facial recognition from DNA refers to the identification or verification of unidentified biological material against facial images with known identity. One approach to establish the identity of unidentified biological material is to predict the face from DNA, and subsequently to match against facial images. However, DNA phenotyping of the human face remains challenging. Here, another proof of concept to biometric authentication is established by using multiple face-to-DNA classifiers, each class...
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#1Nandita Mukhopadhyay (University of Pittsburgh)H-Index: 7
#2Madison Bishop (Emory University)
Last.Mary L. Marazita (University of Pittsburgh)H-Index: 55
view all 19 authors...
Orofacial clefts (OFCs) are one of the most common birth defects worldwide and create a significant health burden. The majority of OFCs are non-syndromic, and the genetic component has been only partially determined. Here, we analyze whole genome sequence (WGS) data for association with risk of OFCs in European and Colombian families selected from a multicenter family-based OFC study. Part of the Gabriella Miller Kids First Pediatric Research Program, this is the first large-scale WGS study of O...
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#1Ziyi Xiong (CAS: Chinese Academy of Sciences)H-Index: 1
#2Gabriela Dankova (EUR: Erasmus University Rotterdam)
Last.Manfred Kayser (EUR: Erasmus University Rotterdam)H-Index: 71
view all 49 authors...
Abstract The human face represents a combined set of highly heritable phenotypes, but knowledge on its genetic architecture remains limited despite the relevance for various fields of science and application. A series of genome-wide association studies on 78 facial shape phenotypes quantified from 3-dimensional facial images of 10,115 Europeans identified 24 genetic loci reaching genome-wide significant association, among which 17 were previously unreported. A multi-ethnic study in additional 7,...
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#1Jenna C. Carlson (University of Pittsburgh)H-Index: 9
#2Deepti Anand (UD: University of Delaware)H-Index: 10
Last.Elizabeth J. Leslie (Emory University)H-Index: 21
view all 21 authors...
1 CitationsSource
#1Seth M. Weinberg (University of Pittsburgh)H-Index: 24
#2Jasmien Roosenboom (University of Pittsburgh)H-Index: 7
Last.Peter Claes (Katholieke Universiteit Leuven)H-Index: 22
view all 6 authors...
1 CitationsSource
Introduction Datasets of soft-tissue craniofacial anthropometric norms collected with the use of different methods are available, but there is little understanding of how the measurements compare. Here we compare a set of standard facial measurements between 2 large datasets: the 3D Facial Norms (3DFN) dataset collected with the use of 3D stereophotogrammetry (n = 2454), and the Farkas craniofacial norms collected with the use of direct anthropometry (n = 2326). Methods A common set of 24 cranio...
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#1Masahiro Takahashi (Showa University)H-Index: 3
#2Tetsutaro Yamaguchi (Showa University)H-Index: 14
Last.Koutaro Maki (Showa University)H-Index: 20
view all 15 authors...
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