Holly Kramer
Loyola University Chicago
Publications 213
#1Sarunas P. Daugirdas (LUC: Loyola University Chicago)
#2Talar Markossian (LUC: Loyola University Chicago)H-Index: 7
Last.Holly Kramer (LUC: Loyola University Chicago)H-Index: 40
view all 6 authors...
Introduction and hypothesis Urinary incontinence is common among older adults with chronic conditions. The purpose of this study is to examine the association of urinary incontinence with chronic conditions in the US population.
#1Meijian Guan (Wake Forest University)H-Index: 5
#2Jacob M. Keaton (Wake Forest University)H-Index: 6
Last.Maggie C.Y. Ng (Wake Forest University)H-Index: 42
view all 27 authors...
End-stage kidney disease (ESKD) is a significant public health concern disproportionately affecting African Americans (AAs). Type 2 diabetes (T2D) is the leading cause of ESKD in the USA, and efforts to uncover genetic susceptibility to diabetic kidney disease (DKD) have had limited success. A prior genome-wide association study (GWAS) in AAs with T2D-ESKD was expanded with additional AA cases and controls and genotypes imputed to the higher density 1000 Genomes reference panel. The discovery an...
1 CitationsSource
#1Alexander TeumerH-Index: 70
#2Yong Li (University of Freiburg)H-Index: 26
Last.Anna Köttgen (Johns Hopkins University)H-Index: 52
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Increased levels of the urinary albumin-to-creatinine ratio (UACR) are associated with higher risk of kidney disease progression and cardiovascular events, but underlying mechanisms are incompletely understood. Here, we conduct trans-ethnic (n = 564,257) and European-ancestry specific meta-analyses of genome-wide association studies of UACR, including ancestry- and diabetes-specific analyses, and identify 68 UACR-associated loci. Genetic correlation analyses and risk score associations in an ind...
#1Alex G. Morris (University of Oxford)H-Index: 89
#2Thu H. Le (UVA: University of Virginia)H-Index: 22
Last.Nora Franceschini (UNC: University of North Carolina at Chapel Hill)H-Index: 52
view all 72 authors...
Chronic kidney disease (CKD) affects ~10% of the global population, with considerable ethnic differences in prevalence and aetiology. We assemble genome-wide association studies of estimated glomerular filtration rate (eGFR), a measure of kidney function that defines CKD, in 312,468 individuals of diverse ancestry. We identify 127 distinct association signals with homogeneous effects on eGFR across ancestries and enrichment in genomic annotations including kidney-specific histone modifications. ...
6 CitationsSource
#1Paul E. Drawz (UMN: University of Minnesota)H-Index: 20
#2Srinivasan Beddhu (UofU: University of Utah)H-Index: 32
Last.Paul K. Whelton (Tulane University)H-Index: 97
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The majority of patients with chronic kidney disease (CKD) have elevated blood pressure (BP). In patients with CKD, hypertension is associated with increased risk for cardiovascular disease, progression of CKD, and all-cause mortality. New guidelines from the American College of Cardiology/American Heart Association (ACC/AHA) recommend new thresholds and targets for the diagnosis and treatment of hypertension in patients with and without CKD. A new aspect of the guidelines is the recommendation ...
#1Holly Kramer (LUC: Loyola University Chicago)H-Index: 40
1 CitationsSource
#1Holly Kramer (LUC: Loyola University Chicago)H-Index: 40
#2Kam Kalantar-Zadeh (UCI: University of California, Irvine)H-Index: 1
#1Holly Kramer (LUC: Loyola University Chicago)H-Index: 40
#2Talar Markossian (RMIT: RMIT University)
Although the association of vitamin D levels with cardiovascular risk profiles among Hispanics/Latinos has been studied, little is known about this association among Hispanics/Latinos with chronic conditions. This pilot study determined serum vitamin D and parathyroid hormone (PTH) levels in a sample of participants from the University of Illinois at the Chicago Cohort of Patients, Family and Friends (UIC Cohort) and examined their association with traditional cardiovascular disease risk factors...
#1Talar Markossian (LUC: Loyola University Chicago)H-Index: 7
#2Holly Kramer (LUC: Loyola University Chicago)H-Index: 40
Last.Kevin T. Stroupe (LUC: Loyola University Chicago)H-Index: 20
view all 9 authors...