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Bodo Philipp
University of Münster
55Publications
20H-index
1,545Citations
Publications 55
Newest
Published in Scientific Reports4.01
Martha N. Mendelski1
Estimated H-index: 1
(WWU: University of Münster),
Ramona Dölling1
Estimated H-index: 1
(WWU: University of Münster)
+ -3 AuthorsBodo Philipp20
Estimated H-index: 20
(WWU: University of Münster)
Bile acids are steroid compounds from the digestive tracts of vertebrates that enter agricultural environments in unusual high amounts with manure. Bacteria degrading bile acids can readily be isolated from soils and waters including agricultural areas. Under laboratory conditions, these bacteria transiently release steroid compounds as degradation intermediates into the environment. These compounds include androstadienediones (ADDs), which are C19-steroids with potential hormonal effects. Exper...
Published on Jul 1, 2018in Bioresource Technology6.67
Elvira Sgobba4
Estimated H-index: 4
,
Anna K. Stumpf1
Estimated H-index: 1
+ 6 AuthorsVolker F. Wendisch53
Estimated H-index: 53
Abstract In the biorefinery concept renewable feedstocks are converted to a multitude of value-added compounds irrespective of seasonal or other variations of the complex biomass substrates. Conceptionally, this can be realized by specialized single microbial strains or by co-culturing various strain combinations. In the latter approach strains for substrate conversion and for product formation can be combined. This study addressed the construction of binary microbial consortia based on starch- ...
Published on Apr 20, 2018in Applied and Environmental Microbiology4.08
Gianna Panasia1
Estimated H-index: 1
,
Bodo Philipp20
Estimated H-index: 20
ABSTRACT The opportunistic pathogen Pseudomonas aeruginosa strain PAO1 is able to use a variety of organic pollutants as growth substrates, including the anionic detergent sodium dodecyl sulfate (SDS) and long-chain alkanes. While the enzymes initiating SDS and alkane degradation are well known, the subsequent enzymatic steps for degradation of the derived primary long-chain alcohols have not yet been identified. By evaluating genes specifically induced during growth with SDS, a gene cluster enc...
Published on Apr 18, 2018in Frontiers in Microbiology4.26
Nina Jagmann8
Estimated H-index: 8
(WWU: University of Münster),
Bodo Philipp20
Estimated H-index: 20
(WWU: University of Münster)
The opportunistic pathogen Pseudomonas aeruginosa employs its complex quorum sensing (QS) network to regulate the expression of virulence factors such as pyocyanin. Besides cell density, QS in this bacterium is co-regulated by environmental cues. In this study, we employed a previously established co-culture model system to identify metabolic influences that are involved in the regulation of pyocyanin production in P. aeruginosa. In this co-culture consisting of P. aeruginosa and the chitinolyti...
Published on Mar 1, 2018in Journal of Microbiological Methods1.80
Karsten Zecher3
Estimated H-index: 3
,
Vishwa Prasad Aitha1
Estimated H-index: 1
+ 4 AuthorsBodo Philipp20
Estimated H-index: 20
Abstract Marine biofouling on artificial surfaces such as ship hulls or fish farming nets causes enormous economic damage. The time for the developmental process of antifouling coatings can be shortened by reliable laboratory assays. For designing such test systems, it is important that toxic effects can be excluded, that multiple parameters can be addressed simultaneously and that mechanistic aspects can be included. In this study, a multi-step approach for testing antifouling coatings was esta...
Published on Jan 26, 2018in Applied and Environmental Microbiology4.08
Markus Warnke3
Estimated H-index: 3
(University of Freiburg),
Tobias Jung3
Estimated H-index: 3
(University of Freiburg)
+ 6 AuthorsMatthias Boll30
Estimated H-index: 30
(University of Freiburg)
ABSTRACT The denitrifying betaproteobacterium Sterolibacterium denitrificans Chol1S catabolizes steroids such as cholesterol via an oxygen-independent pathway. It involves enzyme reaction sequences described for aerobic cholesterol and bile acid degradation as well as enzymes uniquely found in anaerobic steroid-degrading bacteria. Recent studies provided evidence that in S. denitrificans, the cholest-4-en-3-one intermediate is oxygen-independently oxidized to Δ 4 -dafachronic acid (C 26 -oic aci...
Published on Jan 4, 2018in Genome Announcements
Onur Yücel5
Estimated H-index: 5
,
Daniel Wibberg19
Estimated H-index: 19
(Bielefeld University)
+ 1 AuthorsJörn Kalinowski52
Estimated H-index: 52
(Bielefeld University)
ABSTRACT Many bacteria from different phylogenetic groups are able to degrade eukaryotic steroid compounds, but the underlying metabolic pathways are still not well understood. Novosphingobium sp. strain Chol11 is a steroid-degrading alphaproteobacterium. Its genome sequence reveals that it lacks several genes for steroid degradation known to exist in other model organisms.
Published on Oct 20, 2017in Applied and Environmental Microbiology4.08
Onur Yücel5
Estimated H-index: 5
,
Johannes Holert9
Estimated H-index: 9
(UBC: University of British Columbia)
+ 2 AuthorsBodo Philipp20
Estimated H-index: 20
ABSTRACT Bile salts such as cholate are steroid compounds with a C 5 carboxylic side chain and occur ubiquitously in vertebrates. Upon their excretion into soils and waters, bile salts can serve as growth substrates for diverse bacteria. Novosphingobium sp. strain Chol11 degrades 7-hydroxy bile salts via 3-keto-7-deoxy-Δ 4,6 metabolites by the dehydration of the 7-hydroxyl group catalyzed by the 7α-hydroxysteroid dehydratase Hsh2. This reaction has not been observed in the well-studied 9-10-seco...
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