Michael M. Wagner
University of Pittsburgh
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Publications 657
#1Silvia Bulgheresi (University of Vienna)H-Index: 14
#2Gabriela F. Paredes (University of Vienna)H-Index: 1
Last. Claudia Hirschfeld (University of Greifswald)H-Index: 2
view all 14 authors...
Chemosynthetic symbioses occur worldwide in marine habitats. However, physiological studies of chemoautotrophic bacteria thriving on animals are scarce. Stilbonematinae are coated by monocultures of thiotrophic Gammaproteobacteria. As these nematodes migrate through the redox zone, their ectosymbionts experience varying oxygen concentrations. Here, by applying omics, Raman microspectroscopy and stable isotope labeling, we investigated the effect of oxygen on the metabolism of Candidatus Thiosymb...
#1Luca Kleineidam (University of Cologne)H-Index: 6
#2Vincent Chouraki (Pasteur Institute)H-Index: 30
Last. Anne Boland (Université Paris-Saclay)H-Index: 37
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A rare coding variant (rs72824905, p.P522R) conferring protection against Alzheimer’s disease (AD) was identified in the gene encoding the enzyme phospholipase-C-γ2 (PLCG2) that is highly expressed in microglia. To explore the protective nature of this variant, we employed latent process linear mixed models to examine the association of p.P522R with longitudinal cognitive decline in 3595 MCI patients, and in 10,097 individuals from population-based studies. Furthermore, association with CSF leve...
1 CitationsSource
#1Kathrin Heser (University Hospital Bonn)H-Index: 11
#2Luca Kleineidam (University Hospital Bonn)H-Index: 6
Last. Martin Scherer (UHH: University of Hamburg)H-Index: 33
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1 CitationsSource
#1Anne Daebeler (University of Vienna)H-Index: 9
#2Katharina Kitzinger (University of Vienna)H-Index: 4
Last. P Halkjaer Nielsen (AAU: Aalborg University)H-Index: 73
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Nitrite-oxidizing bacteria of the genus Nitrospira are key players of the biogeochemical nitrogen cycle. However, little is known about their occurrence and survival strategies in extreme pH environments. Here, we report on the discovery of physiologically versatile, haloalkalitolerant Nitrospira that drive nitrite oxidation at exceptionally high pH. Nitrospira distribution, diversity, and ecophysiology were studied in hypo- and subsaline, highly alkaline (pH 8.9-10.3) lakes by amplicon sequenci...
#1Kang Soo LeeH-Index: 1
#2Michael M. WagnerH-Index: 121
Last. Roman StockerH-Index: 40
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#1John M. Aronis (University of Pittsburgh)H-Index: 15
#2Jeffrey P. Ferraro (UofU: University of Utah)H-Index: 7
Last. Gregory F. Cooper (University of Pittsburgh)H-Index: 44
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Over the past decade, outbreaks of new or reemergent viruses such as severe acute respiratory syndrome (SARS) virus, Middle East respiratory syndrome (MERS) virus, and Zika have claimed thousands of lives and cost governments and healthcare systems billions of dollars. Because the appearance of new or transformed diseases is likely to continue, the detection and characterization of emergent diseases is an important problem. We describe a Bayesian statistical model that can detect and characteriz...
There are very few studies examining the determinants of frequent attendance in primary care among the oldest old. The purpose of this study was to determine the characteristics of frequent attendance among individuals aged 85 years or older. Cross-sectional data stem from the multicenter prospective cohort “Study on needs, health service use, costs and health-related quality of life in a large sample of oldest old primary care patients (85 +)” (AgeQualiDe). This study covers very old primary ca...
#1Johanna Katharina Hohls (UHH: University of Hamburg)H-Index: 2
#2Hans-Helmut König (UHH: University of Hamburg)H-Index: 47
Last. Susanne Roehr (Leipzig University)H-Index: 6
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AbstractObjectives: This study aimed to examine aspects of help-seeking for psychological distress and its association with increased anxiety symptoms in the oldest old.Method: Baseline data from A...
#1Joo-Han Gwak (CBNU: Chungbuk National University)H-Index: 1
#2Man-Young Jung (University of Vienna)H-Index: 3
Last. Sung-Keun Rhee (CBNU: Chungbuk National University)H-Index: 32
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Consistent with the observation that ammonia-oxidizing bacteria (AOB) outnumber ammonia-oxidizing archaea (AOA) in many eutrophic ecosystems globally, AOB typically dominate activated sludge aeration basins from municipal wastewater treatment plants (WWTPs). In this study, we demonstrate that the growth of AOA strains inoculated into sterile-filtered wastewater was inhibited significantly, in contrast to uninhibited growth of a reference AOB strain. In order to identify possible mechanisms under...
1 CitationsSource
#1Felix S. Hussenoeder (Leipzig University)H-Index: 2
#2I Conrad (Leipzig University)H-Index: 5
Last. Birgitt WieseH-Index: 36
view all 21 authors...
Purpose Mild cognitive impairment (MCI) is a widespread phenomenon, especially affecting older individuals. We will analyze in how far MCI affects different facets of quality of life (QOL).