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Jonathan S. Silver
University of Pennsylvania
34Publications
16H-index
1,839Citations
Publications 34
Newest
Published on Feb 1, 2018in Journal of Electrocardiology1.17
Sunita Sharma6
Estimated H-index: 6
,
Ajay K. Sharma18
Estimated H-index: 18
+ 1 AuthorsJonathan S. Silver16
Estimated H-index: 16
Published on Nov 1, 2017in The American Journal of Medicine4.76
Ajay K. Sharma5
Estimated H-index: 5
,
Nureddin Almaddah1
Estimated H-index: 1
+ 3 AuthorsJonathan S. Silver16
Estimated H-index: 16
Published on Sep 1, 2017in Nature Immunology23.53
Jonathan S. Silver16
Estimated H-index: 16
,
Alison A. Humbles36
Estimated H-index: 36
The cytokine TGF-β allows tumors to evade the immune system by converting conventional natural killer cells into type 1 innate lymphoid cells devoid of cytotoxic function.
Published on Mar 1, 2017in Journal of the American College of Cardiology18.64
Kashif Chaudhry1
Estimated H-index: 1
(Lahey Hospital & Medical Center),
Jonathan S. Silver16
Estimated H-index: 16
(Lahey Hospital & Medical Center)
+ 4 AuthorsMohammed Premjee (Lahey Hospital & Medical Center)
Background: The Closed Chest Convergent Epicardial–Endocardial Ablation procedure uses radiofrequency energy to perform thoracoscopic epicardial ablation and percutaneous endocardial ablation. The effect of such extensive left atrial (LA) ablation on LA mechanical function is unknown. Methods: We
Published on Feb 1, 2017in Cell Reports7.82
Arielle Glatman Zaretsky3
Estimated H-index: 3
(UPenn: University of Pennsylvania),
Christoph Konradt5
Estimated H-index: 5
(UPenn: University of Pennsylvania)
+ 17 AuthorsWilliam J. Quinn18
Estimated H-index: 18
(UPenn: University of Pennsylvania)
Summary Long-lived plasma cells (PCs) in the bone marrow (BM) are a critical source of antibodies after infection or vaccination, but questions remain about the factors that control PCs. We found that systemic infection alters the BM, greatly reducing PCs and regulatory T (Treg) cells, a population that contributes to immune privilege in the BM. The use of intravital imaging revealed that BM Treg cells display a distinct behavior characterized by sustained co-localization with PCs and CD11c-YFP ...
Published on Jun 1, 2016in Nature Immunology23.53
Jonathan S. Silver16
Estimated H-index: 16
(MedImmune),
Jennifer Kearley4
Estimated H-index: 4
(MedImmune)
+ 10 AuthorsRussell P. Bowler42
Estimated H-index: 42
Group 1 and 3 innate lymphoid cells can be functionally plastic. Humbles and colleagues find that group 2 innate lymphoid cells in the lungs also exhibit phenotypic plasticity after exposure to infectious or noxious agents.
Published on Jun 1, 2016in Nature Immunology23.53
Yoichiro Ohne2
Estimated H-index: 2
(MedImmune),
Jonathan S. Silver16
Estimated H-index: 16
(MedImmune)
+ 6 AuthorsYong-Jun Liu15
Estimated H-index: 15
(MedImmune)
Cytokines of the IL-1 family have a range of effects on innate lymphoid cells. Liu and colleagues find that IL-1 facilitates the maturation and plasticity of group 2 innate lymphoid cells.
Published on Mar 1, 2015in Immunity21.52
Jennifer Kearley4
Estimated H-index: 4
(MedImmune),
Jonathan S. Silver16
Estimated H-index: 16
(MedImmune)
+ 12 AuthorsGj. Criner45
Estimated H-index: 45
(TU: Temple University)
Summary Cigarette smoking is a major risk factor for chronic obstructive pulmonary disease and is presumed to be central to the altered responsiveness to recurrent infection in these patients. We examined the effects of smoke priming underlying the exacerbated response to viral infection in mice. Lack of interleukin-33 (IL-33) signaling conferred complete protection during exacerbation and prevented enhanced inflammation and exaggerated weight loss. Mechanistically, smoke was required to upregul...
Published on Feb 1, 2015in Journal of Cardiac Failure3.86
Timothy S. Draper1
Estimated H-index: 1
(Tufts University),
Jonathan S. Silver16
Estimated H-index: 16
(Tufts University),
William H. Gaasch88
Estimated H-index: 88
(Tufts University)
Abstract Background The relationship of life-threatening ventricular arrhythmias to specific patterns of adverse LV remodeling has not been reported. We examined the relationship of ventricular tachycardia and/or fibrillation (VT/VF) to the pattern of left ventricular (LV) structural remodeling and to the degree of LV dysfunction in patients with a low ejection fraction (EF). Methods and Results Data from 127 patients with a low EF (≤0.45) and an implantable cardioverter-defibrillator (ICD) were...
Published on Feb 14, 2014in PLOS ONE2.78
Alba Llop-Guevara9
Estimated H-index: 9
(McMaster-Carr),
Derek K. Chu13
Estimated H-index: 13
(McMaster-Carr)
+ 11 AuthorsAnthony J. Coyle34
Estimated H-index: 34
(Pfizer)
Allergic asthma is a chronic immune-inflammatory disease of the airways. Despite aeroallergen exposure being universal, allergic asthma affects only a fraction of individuals. This is likely related, at least in part, to the extent of allergen exposure. Regarding house dust mite (HDM), we previously identified the threshold required to elicit allergic responses in BALB/c mice. Here, we investigated the impact of an initial immune perturbation on the response to sub-threshold HDM exposure. We sho...
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