Duncan Wilson
University College London
Publications 626
#1Robyn M. StuartH-Index: 4
#2Sherrie L. KellyH-Index: 7
Last.Duncan WilsonH-Index: 57
view all 4 authors...
#1Anna Palmer (Burnet Institute)H-Index: 2
#2Amanda Wade (Barwon Health)H-Index: 6
Last.Nick Scott (Monash University, Clayton campus)H-Index: 11
view all 10 authors...
Abstract Background Hepatitis C virus elimination may be possible by scaling up direct-acting antiviral (DAA) treatment. Due to the safety and simplicity of DAA treatment, primary care-based treatment delivery is now feasible, efficacious and may be cheaper than hospital-based specialist care. In this paper, we use Prime Study data – a randomised controlled trial comparing the uptake of DAA treatment between primary and hospital-based care settings amongst people who inject drugs (PWID) – to est...
#1Isabel Charlotte Hostettler (UCL: University College London)H-Index: 3
#2Matthew J Morton (University of Southampton)
Last.David J. Werring (UCL: University College London)H-Index: 40
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Objective Haptoglobin is a haemoglobin-scavenging protein that binds and neutralises free haemoglobin and modulates inflammation and endothelial progenitor cell function. A HP gene copy number variation (CNV) generates HP1 and HP2 alleles, while the single-nucleotide polymorphism rs2000999 influences their levels. The HP1 allele is hypothesised to improve outcome after spontaneous (non-traumatic) intracerebral haemorrhage (ICH). We investigated the associations of the HP CNV genotype and rs20009...
#1Joel Elliot Dane Stanton (UCL: University College London)H-Index: 1
#2Arvind Chandratheva (UCL: University College London)
Last.David J. Werring (UCL: University College London)H-Index: 40
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Objective To identity clinical features that distinguish between cerebral amyloid angiopathy (CAA)-associated convexity subarachnoid haemorrhage (cSAH) and suspected TIA.
2 CitationsSource
#1Nick Scott (Monash University, Clayton campus)H-Index: 11
#2Duncan Wilson (Monash University, Clayton campus)H-Index: 57
Last.Margaret HellardH-Index: 50
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The introduction of highly effective direct-acting antiviral (DAA) therapy for hepatitis C has led to calls to eliminate it as a public health threat through treatment-as-prevention. Recent studies suggest it is possible to develop a vaccine to prevent hepatitis C. Using a mathematical model, we examined the potential impact of a hepatitis C vaccine on the feasibility and cost of achieving the global WHO elimination target of an 80% reduction in incidence by 2030 in the era of DAA treatment. The...
1 CitationsSource
#1Anupam Datta Gupta (University of Adelaide)H-Index: 2
#2Renuka Visvanathan (University of Adelaide)H-Index: 22
Last.Duncan Wilson (University of Adelaide)H-Index: 57
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Background Post-stroke lower limb spasticity (PSLLS) has a prevalence of 28–37%. PSLLS can cause difficulty in walking and reduce quality of life (QOL). Post stroke spasticity impairs the ability to intervene to improve walking ability. Botulinum Toxin A (BT) is an effective intervention for focal spasticity, but its use is currently restricted in many countries by their reimbursement system stating that the evidence for improvement in walking and quality of life (QOL) is not robust for treatmen...
1 CitationsSource
#1David J. Kedziora (Monash University)H-Index: 15
#2Robyn M. Stuart (UCPH: University of Copenhagen)H-Index: 4
Last.Cliff C. Kerr (USYD: University of Sydney)H-Index: 15
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Health resources are limited, which means spending should be focused on the people, places and programs that matter most. Choosing the mix of programs to maximize a health outcome is termed allocative efficiency. Here, we extend the methodology of allocative efficiency to answer the question of how resources should be distributed among different geographic regions. We describe a novel geographical optimization algorithm, which has been implemented as an extension to the Optima HIV model. This al...
#1Sophie J. S. Pascoe (University of the Witwatersrand)H-Index: 2
#2Matthew P. Fox (BU: Boston University)H-Index: 46
Last.Nicole Fraser-Hurt (World Bank Group)H-Index: 6
view all 10 authors...
#1H Prudden (Lond: University of London)H-Index: 5
#2Zindoga Mukandavire (Coventry University)
Last.Charlotte Watts (Lond: University of London)H-Index: 59
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Background: In West Africa HIV prevalence varies between 0.1-6% in female and between 0.1-4% in the male general population. Male circumcision is almost universal, and it is unclear what drives this variation. We use mathematical modelling to identify the determinants of this variation across fourteen West African countries. Methods: We developed a novel dynamic model of HIV transmission between population cohorts of female sex workers (FSWs), their clients, females with 2+ partners in the past ...