Branding/Logomark minus Citation Combined Shape Icon/Bookmark-empty Icon/Copy Icon/Collection Icon/Close Copy 7 no author result Created with Sketch. Icon/Back Created with Sketch. Match!
Eva Carro
Cajal Institute
103Publications
33H-index
4,580Citations
Publications 103
Newest
Published on Feb 12, 2019in International Journal of Molecular Sciences 3.69
Carmen Vida8
Estimated H-index: 8
,
Hikaru Kobayashi + 4 AuthorsMónica De la Fuente38
Estimated H-index: 38
In Parkinson’s Disease (PD), the peripheral changes in the functional capacity and redox state of immune cells has been scarcely investigated, especially in the early PD stages. Aging is a risk factor for PD, and the age-related impairment of the immune system, based on a chronic-oxidative stress situation, is involved in the rate of aging. We analyzed several functions in isolated peripheral blood neutrophils and mononuclear cells from PD stage 2 patients, and compared the results to those in h...
Source Cite
Published on Jan 10, 2019in JMIR Research Protocols
Jesús Hernández-Gallego5
Estimated H-index: 5
,
Sara Llamas-Velasco4
Estimated H-index: 4
+ 17 AuthorsRocío Trincado12
Estimated H-index: 12
Source Cite
Published on Dec 1, 2018in Alzheimer's Research & Therapy
F. Bartolomé23
Estimated H-index: 23
,
Macarena de la Cueva1
Estimated H-index: 1
+ 5 AuthorsEva Carro33
Estimated H-index: 33
The phosphodiesterase (PDE) 7 inhibitor S14 is a cell-permeable small heterocyclic molecule that is able to cross the blood–brain barrier. We previously found that intraperitoneal treatment with S14 exerted neuroprotection in an Alzheimer’s disease (AD) model (in APP/PS1 mice). The objective of this study was to investigate the neurogenic and cellular effects of oral administration of S14 on amyloid β (Aβ) overload. We orally administered the PDE7 inhibitor S14 (15 mg/kg/day) or vehicle in 6-mon...
6 Citations Source Cite
Published on Dec 1, 2018in Molecular Neurobiology 5.08
Marta González-Sánchez1
Estimated H-index: 1
,
Teresa Díaz + 6 AuthorsEva Carro33
Estimated H-index: 33
Platelets are considered a good model system to study a number of elements associated with neuronal pathways as they share biochemical similarities. Platelets represent the major source of amyloid-β (Aβ) in blood contributing to the Aβ accumulation in the brain parenchyma and vasculature. Peripheral blood platelet alterations including cytoskeletal abnormalities, abnormal cytoplasmic calcium fluxes or increased oxidative stress levels have been related to Alzheimer’s disease (AD) pathology. Ther...
Source Cite
Published on Dec 1, 2018in Scientific Reports 4.12
Fernando Bartolomé9
Estimated H-index: 9
(UCL Institute of Neurology),
Noemí Esteras11
Estimated H-index: 11
(UCL Institute of Neurology)
+ 9 AuthorsJohn Hardy149
Estimated H-index: 149
(UCL Institute of Neurology)
A correction has been published and is linked to the HTML and PDF versions of this paper. The error has not been fixed in the paper.
Source Cite
Published on Sep 1, 2018in Molecular Neurobiology 5.08
Miren Ettcheto9
Estimated H-index: 9
(University of Barcelona),
Elena Sánchez-López8
Estimated H-index: 8
(University of Barcelona)
+ 10 AuthorsCarme Auladell20
Estimated H-index: 20
(University of Barcelona)
There is growing evidence that obesity associated with type 2 diabetes mellitus (T2DM) and aging are risk factors for the development of Alzheimer’s disease (AD). However, the molecular mechanisms through which obesity interacts with β-amyloid (Aβ) to promote cognitive decline remains poorly understood. Memantine (MEM), a N-methyl-d-aspartate receptor antagonist, is currently used for the treatment of AD. Nonetheless, few studies have reported its effects on genetic preclinical models of this ne...
1 Citations Source Cite
Published on Jun 1, 2018in CNS Drugs 4.21
Patricia del Cerro1
Estimated H-index: 1
(CSIC: Spanish National Research Council),
Carolina Alquézar7
Estimated H-index: 7
(CSIC: Spanish National Research Council)
+ 6 AuthorsÁngeles Martín-Requero14
Estimated H-index: 14
(CSIC: Spanish National Research Council)
Background Alzheimer’s disease is a multifactorial disorder for which there is no disease-modifying treatment yet. CB2 receptors have emerged as a promising therapeutic target for Alzheimer’s disease because they are expressed in neuronal and glial cells and their activation has no psychoactive effects.
1 Citations Source Cite
Published on Jun 1, 2018in Molecular Neurobiology 5.08
Miren Ettcheto9
Estimated H-index: 9
(University of Barcelona),
Sonia Abad9
Estimated H-index: 9
(University of Barcelona)
+ 11 AuthorsCarme Auladell20
Estimated H-index: 20
(University of Barcelona)
The molecular basis of memory loss in Alzheimer’s disease (AD), the main cause of senile dementia, is under investigation. In the present study, we have focused on the early hippocampal memory-related changes in APPswe/PS1dE9 (APP/PS1) mice, a well-established mouse model of familial AD. It is well known that molecules like cAMP response element binding (CREB) and binding protein (CBP) play a crucial role in memory consolidation. We analyzed CBP on its transcriptional activity and protein levels...
3 Citations Source Cite
Published on Mar 1, 2018in Cell Transplantation 2.88
Joana Figueiro-Silva1
Estimated H-index: 1
,
Desiree Antequera15
Estimated H-index: 15
+ 5 AuthorsEva Carro33
Estimated H-index: 33
Neurogenesis in the adult hippocampus is a unique process in neurobiology that requires functional integration of newly generated neurons, which may disrupt existing hippocampal network connections and consequently loss of established memories. As neurodegenerative diseases characterized by abnormal neurogenesis and memory dysfunctions are increasing, the identification of new anti-aging drugs is required. In adult mice, we found that melatonin, a well-established neurogenic hormone, and the mel...
1 Citations Source Cite
Published on Feb 1, 2018in Chronobiology International 2.64
Telma Quintela10
Estimated H-index: 10
(UBI: University of Beira Interior),
T.G. Albuquerque11
Estimated H-index: 11
(UBI: University of Beira Interior)
+ 5 AuthorsCecília R. A. Santos13
Estimated H-index: 13
(UBI: University of Beira Interior)
ABSTRACTThe suprachiasmatic nucleus (SCN) of the hypothalamus is considered the master circadian oscillator in mammals. However, extra-SCN structures in the brain also display daily rhythms. Recently, we have demonstrated that the choroid plexus (CP) expresses core clock genes that are subjected to circadian regulation in a sex-dependent manner. By using CP explants cultured from female knock-in mice carrying the Period-luciferase transgene, we show that CP exhibits endogenous circadian rhythms ...
2 Citations Source Cite
12345678910