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Jürgen Braun
Ruhr University Bochum
PathologyPhysical therapyAnkylosing spondylitisRheumatoid arthritisMedicine
653Publications
88H-index
29.2kCitations
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Publications 597
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#1A. Berrisch (RUB: Ruhr University Bochum)
#1Lihi Eder (Women's College Hospital)H-Index: 28
Last. B. Buehring (RUB: Ruhr University Bochum)H-Index: 1
view all 8 authors...
Background: Cardio-metabolic abnormalities are common in patients with inflammatory arthritis (IA) but tend to be under-recognized and under-treated. Objectives: We aimed to compare the prevalence and risk factors for cardio-metabolic abnormalities between patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS). Methods: Consecutive patients enrolled in the University of Toronto Cardio-Rheumatology Network from July 2017 to August 2019 were analyzed. Th...
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#1Anne C. RegiererH-Index: 2
#2Anja WeißH-Index: 10
Last. Anja StrangfeldH-Index: 18
view all 9 authors...
Background: Axial spondyloarthritis (axSpA) is a potentially severe chronic inflammatory disease with impact on function and quality of life. About 20-30% of axSpA patients show symptoms of depression or are diagnosed with depression [1]. Depression may influence outcome, especially patient reported outcomes. Objectives: To assess differences in baseline characteristics and outcome parameters between patients with and without symptoms of depression using WHO-5 score. Methods: RABBIT-SpA is a pro...
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#1Uta Kiltz (RUB: Ruhr University Bochum)H-Index: 15
#2R. Kempin (RUB: Ruhr University Bochum)
Last. Jürgen Braun (RUB: Ruhr University Bochum)H-Index: 88
view all 8 authors...
Background: Assessment and monitoring of disease activity and functioning is of major importance for the course of axial spondyloarthritis (axSpA). This is equally important for patient monitoring in daily routine as also for tight control strategies. Even though there is evidence that a closer monitoring of patients is better than routine care, more intensive treatment schedules are often not realized in daily practice for several reasons including shortage of time and personal resources. Using...
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#1Xenofon Baraliakos (RUB: Ruhr University Bochum)H-Index: 41
#2A. RichterH-Index: 7
Last. Jürgen Braun (RUB: Ruhr University Bochum)H-Index: 88
view all 7 authors...
Background: Taking advantage of a large population-based study we have recently reported that the frequency of bone marrow edema (BME) and fatty lesions (FL) in the sacroiliac joints (SIJ) and the spine of individuals Objectives: To identify and compare factors associated with the extension of MRI lesions in the spine and the SIJ in the general population. Methods: All available spinal- (sagittal T1/T2 sequences) and SIJ- (semicoronal STIR sequences) MRIs were evaluated by two trained readers bl...
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#1Uta Kiltz (RUB: Ruhr University Bochum)H-Index: 15
#2Jessica A. Walsh (UofU: University of Utah)H-Index: 13
Last. E. Blue (Eli Lilly and Company)
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Background: Ixekizumab has demonstrated efficacy in treating signs and symptoms of patients with non-radiographic axial spondyloarthritis (nr-axSpA).1 The Assessment of SpondyloArthritis International Society Health Index (ASAS HI) is a composite measure consisting of 17 dichotomous items to assess overall functioning and health in patients with spondyloarthritis.2 Objectives: To assess health outcomes using ASAS HI in patients with nr-axSpA treated with ixekizumab (IXE) for 52 weeks. Methods: C...
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#1Xenofon Baraliakos (RUB: Ruhr University Bochum)H-Index: 41
#2Styliani Tsiami (RUB: Ruhr University Bochum)
Last. M. FruthH-Index: 1
view all 11 authors...
OBJECTIVE Chronic inflammatory back pain (IBP) is frequently reported in axial SpA (axSpA) but also in the general population. We evaluated a recently proposed two-step referral system for early recognition of axSpA in primary care and compare it with other combinations of symptoms and SpA-related items. METHODS Consecutive chronic back pain patients ≤45 years of age answered a questionnaire and were seen by a primary care physician who decided whether HLA-B27 needed to be determined. They were ...
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#1Rosalinde Stal (LUMC: Leiden University Medical Center)
#2Floris A. van Gaalen (LUMC: Leiden University Medical Center)H-Index: 16
Last. Xenofon Baraliakos (RUB: Ruhr University Bochum)H-Index: 41
view all 8 authors...
OBJECTIVES: To evaluate the occurrence and progression of facet joint ankylosis in the whole spine using low-dose CT (ldCT) in radiographic axial spondyloarthritis (r-axSpA) and compare progression of facet joint ankylosis and syndesmophytes. METHODS: Patients with r-axSpA from the Sensitive Imaging in Ankylosing Spondylitis (SIAS) cohort underwent ldCT at baseline (n = 60) and 2 years (n = 53). Facet joints (right and left, levels C2-S1) were scored as ankylosed, not ankylosed or unable to asse...
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#1Xenofon Baraliakos (RUB: Ruhr University Bochum)H-Index: 41
#2Kay-Geert A. Hermann (Charité)H-Index: 39
Last. Jürgen Braun (RUB: Ruhr University Bochum)H-Index: 88
view all 5 authors...
OBJECTIVES: We aimed to assess relationships between single Bath Ankylosing Spondylitis Metrology Index (BASMI) components and corresponding spinal segment magnetic resonance images (MRI) in anti-tumour-necrosis-factor-treated AS patients. METHODS: Using available MRI and BASMI data from the GO-RAISE trial (n=91 patients), MRI scores for active inflammatory (ASspiMRI-a) and chronic structural (ASspiMRI-c) changes in cervical and lumbar spine segments were compared with BASMI cervical (cervical-r...
#1Jürgen Braun (RUB: Ruhr University Bochum)H-Index: 88
#2Styliani Tsiami (RUB: Ruhr University Bochum)
Last. Uta Kiltz (RUB: Ruhr University Bochum)H-Index: 15
view all 7 authors...
In Deutschland sind seit vielen Jahren Biosimilars zugelassen, seit wenigen Jahren auch in der Rheumatologie. Zwar haben die Biosimilars, die wie die Referenzbiologika biotechnologisch hergestellten Produkte sind, inzwischen in einigen Regionen schon erheblich Marktanteile erreicht, es gibt aber bei Patienten und Arzten immer noch viele Zweifler, die einen Qualitatsverlust befurchten – auch, wenn es dafur keinen Anhalt gibt. Ein Teil dieses Problems ist durch den Nocebo-Effekt zu erklaren, der a...
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#1Jürgen Braun (RUB: Ruhr University Bochum)H-Index: 88
#2Xenofon Baraliakos (RUB: Ruhr University Bochum)H-Index: 41
Last. Timm H. Westhoff (RUB: Ruhr University Bochum)H-Index: 11
view all 3 authors...
Abstract The term non-steroidal anti-inflammatory drugs (NSAIDs) covers a heterogeneous group of compounds that possess analgesic, antipyretic and anti-inflammatory properties. NSAIDs are recommended as first-line therapy in patients with ankylosing spondylitis (AS) and are also frequently used in rheumatoid arthritis (RA). However, adverse reactions are relatively common, including an increased risk for cardiovascular events which has remained a concern for both, patients and physicians, and th...
5 CitationsSource
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