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Joon Ha Park
Hallym University
201Publications
17H-index
1,146Citations
Publications 201
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#1Tae-Kyeong LeeH-Index: 5
#2Young-Eun ParkH-Index: 13
Last.Ji Hyeon AhnH-Index: 12
view all 9 authors...
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#1Joon Ha Park (Hallym University)H-Index: 17
#2Tae-Kyeong Lee (Kangwon National University)H-Index: 5
Last.Ji Hyeon Ahn (Hallym University)H-Index: 12
view all 10 authors...
Histone-binding protein RbAp48 has been known to be involved in histone acetylation, and epigenetic alterations of histone modifications are closely associated with the pathogenesis of ischemic reperfusion injury. In the current study, we investigated chronological change of RbAp48 expression in the hippocampus following 5 min of transient ischemia in gerbils. RbAp48 expression was examined 1, 2, 5, and 10 days after transient ischemia using immunohistochemistry. In sham operated gerbils, RbAp48...
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#1Bich Na ShinH-Index: 8
#2Dae-Won KimH-Index: 26
Last.Jae-Chul Lee (Kangwon National University)H-Index: 14
view all 14 authors...
Abnormal activation of cyclin-dependent kinase 5 (Cdk5) is associated with pathophysiological conditions. Ischemic preconditioning (IPC) can provide neuroprotective effects against subsequent lethal ischemic insult. The objective of this study was to determine how Cdk5 and related molecules could affect neuroprotection in the hippocampus of gerbils after with IPC [a 2-min transient cerebral ischemia (TCI)] followed by 5-min subsequent TCI. Hippocampal CA1 pyramidal neurons were dead at 5 days po...
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#1Ji Hyeon AhnH-Index: 12
#2Bich Na ShinH-Index: 8
Last.Hyeyoung KimH-Index: 34
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Oxcarbazepine, an antiepileptic drug, has been reported to modulate voltage-dependent sodium channels, and it is commonly used in epilepsy treatment. In this study, we investigated the neuroprotective effect of oxcarbazepine in the hippocampus after transient ischemia in gerbils. Gerbils randomly received oxcarbazepine 100 or 200 mg/kg before and after transient ischemia. We examined its neuroprotective effect in the cornu ammonis 1 subfield of the gerbil hippocampus at 5 days after transient is...
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#1Joon Ha Park (Dongguk University)H-Index: 17
#2Dae Won Kim (Gangneung–Wonju National University)H-Index: 7
Last.Choong Hyun Lee (DU: Dankook University)H-Index: 24
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#1Joon Ha ParkH-Index: 17
#2Ji Hyeon AhnH-Index: 12
Last.Soo Young ChoiH-Index: 23
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A brief episode of transient ischemia (TI) can confer cerebral ischemic tolerance against a subsequent severer TI under standard condition. The brain under obesity’s conditions is more sensitive to ischemic injury. However, the impact of a brief episode of TI under obesity’s conditions has not been fully addressed yet. Thus, the objective of this study was to determine the effect of a brief TI in the hippocampus of high-fat diet (HFD)-induced obese gerbils and related mechanisms. Gerbils were ma...
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Compelling evidence from preclinical and clinical studies has shown that mild hypothermia is neuroprotective against ischemic stroke. We investigated the neuroprotective effect of post-risperidone (RIS) treatment against transient ischemic injury and its mechanisms in the gerbil brain. Transient ischemia (TI) was induced in the telencephalon by bilateral common carotid artery occlusion (BCCAO) for 5 min under normothermic condition (37 ± 0.2 °C). Treatment of RIS induced hypothermia until 12 h a...
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#2Jaelim ChoH-Index: 25
Last.Moo-Ho WonH-Index: 41
view all 11 authors...
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#2Jaelim ChoH-Index: 25
Last.Moo-Ho WonH-Index: 41
view all 11 authors...
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