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Andrea Granados
Washington University in St. Louis
EndocrinologyGonadal dysgenesisCystic fibrosis-related diabetesDiabetes mellitusMedicine
10Publications
3H-index
41Citations
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Publications 12
Newest
#1Katie Larson Ode (Boston Children's Hospital)H-Index: 10
#2Christine L. Chan (CU: University of Colorado Boulder)H-Index: 6
Last. Amanda L. BrennanH-Index: 10
view all 6 authors...
Abstract Cystic Fibrosis Related Diabetes Mellitus (CFRD) drives excess pulmonary morbidity and mortality in patients with cystic fibrosis (CF). The recommended treatment is insulin therapy. Insulin therapy in CF should be customized to the specific patient. CF patients typically require intensive insulin regimens such as multiple daily injections or insulin pump therapy, but frequently require lower doses than in type 1 diabetes mellitus. Patients with CF may also need insulin to cover intraven...
2 CitationsSource
#1Andrea Granados (WashU: Washington University in St. Louis)H-Index: 3
#2Christine L. Chan (University of Colorado Denver)H-Index: 6
Last. Reinhard W. Holl (University of Ulm)H-Index: 53
view all 6 authors...
ABSTRACT Cystic fibrosis related diabetes (CFRD) is a distinct form of diabetes that is associated with significantly increased morbidity and mortality in the CF population. The primary etiology is relative insulin insufficiency secondary to destruction of pancreatic islets, and to other factors that affect the function of the remaining beta cells. The prevalence of CFRD increases markedly with age and more than half of CF adults develop the disease. As the initial presentation of CFRD may be cl...
2 CitationsSource
#1Amir MoheetH-Index: 11
#2Christine L. Chan (University of Colorado Denver)H-Index: 6
Last. Alberto Battezzati (University of Milan)H-Index: 25
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Abstract Hypoglycemia is a common and feared complication of insulin therapy. As in type 1 and type 2 diabetes, people with cystic fibrosis related diabetes are also at risk for hypoglycemia related to insulin therapy. Spontaneous hypoglycemia is also common in patients with CF without diabetes, who are not on glucose lowering medications. Spontaneous hypoglycemia in CF may also occur during or after an oral glucose tolerance test. In this review, we will discuss the definition, epidemiology, pa...
2 CitationsSource
#1Christine L. Chan (CU: University of Colorado Boulder)H-Index: 6
#2Katie Larson Ode (Boston Children's Hospital)H-Index: 10
Last. Shihab HameedH-Index: 9
view all 6 authors...
ABSTRACT Our ability to monitor blood glucose levels has become increasingly accurate over the last few decades. Continuous glucose monitoring (CGM) technology now allows providers and patients the ability to monitor glucose levels retrospectively as well as in real-time for diabetes management. CGM also provides the ability to study glucose patterns and trends for insight into the pathophysiology and natural history of disease. CGM captures a more complete picture of glucose profiles than tradi...
3 CitationsSource
#1Andrea Granados (WashU: Washington University in St. Louis)H-Index: 3
#2Achamyeleh Gebremariam (UM: University of Michigan)H-Index: 27
Last. Joyce M. Lee (UM: University of Michigan)H-Index: 36
view all 8 authors...
1 CitationsSource
#1Paulina Cruz (WashU: Washington University in St. Louis)H-Index: 1
#2Andrea Granados (WashU: Washington University in St. Louis)H-Index: 3
Latino youth have the highest prevalence of overweight and obesity among all ethnic groups and are disproportionally affected by pre diabetes and type 2 diabetes (T2DM). Interventions that effectively reduce the risk of pre diabetes and T2DM in this population are urgently needed. Studies have shown that without any change, 50% of Latino children and adolescents will develop T2DM. This has important public health implications. Few pharmacologic options are approved for use in the pediatric popul...
Source
#1Brandon M. Nathan (UMN: University of Minnesota)H-Index: 58
#2Kubendran PillayH-Index: 3
Last. Carlo L. Acerini (University of Cambridge)H-Index: 43
view all 6 authors...
2 CitationsSource
#1Andrea Granados (UM: University of Michigan)H-Index: 3
#2Veronica I. Alaniz (UM: University of Michigan)H-Index: 4
Last. Catherine E. Keegan (UM: University of Michigan)H-Index: 18
view all 9 authors...
Investigation of disorders of sex development (DSD) has resulted in the discovery of multiple sex-determining genes. MAP3K1 encodes a signal transduction regulator in the sex determination pathway and is emerging as one of the more common genes responsible for 46,XY DSD presenting as complete or partial gonadal dysgenesis. Clinical assessment, endocrine evaluation, and genetic analysis were performed in six individuals from four unrelated families with 46,XY DSD. All six individuals were found t...
8 CitationsSource
#1Andrea Granados (UM: University of Michigan)H-Index: 3
#2Achamyeleh Gebremariam (UM: University of Michigan)H-Index: 27
Last. Joyce M. LeeH-Index: 36
view all 3 authors...
Growth and pubertal development are important health markers. We used the data of a longitudinal growth study on a contemporary sample of US youth to examine the relationship between peak height velocity (PHV) and Tanner staging. We observed a substantial variability in the timing of PHV across Tanner stages, which is an important consideration for clinicians when assessing growth.
27 CitationsSource
#1Veronica I. Alaniz (UM: University of Michigan)H-Index: 4
#2Andrea Granados (UM: University of Michigan)H-Index: 3
Last. Elisabeth H. Quint (UM: University of Michigan)H-Index: 20
view all 6 authors...
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