Hemali Mehta
Tata Institute of Fundamental Research
VirologyImmunologyHepatitis CPopulationMedicine
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Publications 291
#1Bohdan Nosyk (SFU: Simon Fraser University)H-Index: 26
#2Emanuel KrebsH-Index: 6
Last. Matthew R. Golden (UW: University of Washington)H-Index: 41
view all 18 authors...
: We estimated HIV incidence and incidence rate ratios (IRR) for Blacks and Hispanics versus Whites in six US cities (2020-2030). Large reductions in incidence are possible, but without elimination of disparities in healthcare access, we found wide disparities for Blacks to Whites in particular persisted (lowest IRR:1.69[95%CrI,1.19-2.30]).
#1Steven J. Clipman (Johns Hopkins University)H-Index: 1
#2Priya Duggal (Johns Hopkins University)H-Index: 32
Last. Sunil S. Solomon (Johns Hopkins University)H-Index: 24
view all 10 authors...
BACKGROUND: Data from high-income countries suggest increasing hepatitis C virus (HCV) prevalence/incidence among HIV-infected men who have sex with men (MSM), but limited data derive from low-and-middle-income countries (LMICs). METHODS: We recruited 4,994 MSM from 5 states across India using respondent-driven sampling (RDS). Logistic regression incorporating RDS weights and machine learning feature selection were used to identify correlates of prevalent HCV, and Bayesian phylogenetic analysis ...
1 CitationsSource
#1Risha Irvin (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 2
#2Geetanjali Chander (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 27
Last. Mark S. Sulkowski (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 77
view all 15 authors...
We investigated the prevalence and impact of heavy alcohol use on the hepatitis C virus (HCV) care continuum amongst HIV/HCV co-infected persons who use drugs. In the CHAMPS study, 144 HIV/HCV co-infected persons were randomized to contingent cash incentives, peer mentors and usual care to evaluate the impact on HCV care. Alcohol use was ascertained using the 10-item AUDIT (hazardous: male >/=8, female >/=4) and phosphatidylethanol (PEth) (heavy: >/=50 ng/mL), an alcohol biomarker. Log binomial ...
#1Mary A. RodgersH-Index: 7
Last. Gavin ClohertyH-Index: 12
view all 8 authors...
Although the prevalences of HIV and HCV are significantly higher amongst PWID in India compared to the general population, the strains circulating within this group have not been well-characterized. Through subgenomic sequencing of viruses present in residual plasma from an HIV/HCV prevalence study conducted amongst PWID across five cities in India in 2016–2017, a total of N = 498 HCV and N = 755 HIV strains were classified from N = 975 study participants. Considerable HCV diversity was identifi...
#1Damani Arnold Piggott (Johns Hopkins University)H-Index: 7
#2Karen Bandeen-RocheH-Index: 65
Last. Gregory D KirkH-Index: 48
view all 8 authors...
OBJECTIVE: Frailty is a critical aging-related syndrome marked by diminished physiologic reserve and heightened vulnerability to stress, predictive of major adverse clinical outcomes in HIV-infected and uninfected adults. Frailty is a dynamic state, yet little data exist on predictors and consequences of frailty transitions. DESIGN/METHODS: Frailty was assessed semiannually among HIV-infected and uninfected persons with prior injection drug use (PWID) using the 5 Fried phenotype domains. An infl...
#1Oluwaseun Falade-Nwulia (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 10
#2Paul L. Sacamano (Johns Hopkins University)H-Index: 2
Last. Hemali Mehta (Johns Hopkins University)H-Index: 54
view all 9 authors...
Abstract Background Hepatitis C virus (HCV) treatment uptake among people who inject drugs (PWID), a population with disproportionately high rates of HCV, remains low. Peers have been shown to positively impact a broad range of health outcomes for PWID. There is, however, limited data on the impact of PWID social network members on HCV treatment. Methods HCV-infected PWID enrolled in an ongoing community-based cohort were recruited as “indexes” to complete an egocentric social network survey. Th...
#1Denali Boon (Johns Hopkins University)H-Index: 2
#2Veronica R. Bruce (UNM: University of New Mexico)H-Index: 1
Last. Gregory D Kirk (Johns Hopkins University)H-Index: 48
view all 17 authors...
BACKGROUND & AIMS: Accurate hepatitis C virus (HCV) incidence estimates are critical for monitoring progress towards HCV elimination goals, including an 80% reduction in HCV incidence by 2030. Moreover, incidence estimates can help guide prevention and treatment programming, particularly in the context of the US opioid epidemic. METHODS: An inexpensive, Genedia-based HCV IgG antibody avidity assay was evaluated as a platform to estimate cross-sectional, population-level primary HCV incidence usi...
#1Megan E. Buresh (Johns Hopkins University)H-Index: 1
#2Rachel Gicquelais (Johns Hopkins University)H-Index: 1
Last. Becky Genberg (Johns Hopkins University)H-Index: 19
view all 6 authors...
Introduction Overdose is a leading cause of death in the United States, especially among people who inject drugs (PWID). Improving naloxone access and carrying among PWID may offset recent increases in overdose mortality associated with the influx of synthetic opioids in the drug market. This study characterized prevalence and correlates of several naloxone outcomes among PWID. Methods During 2018, a survey to assess experience with naloxone was administered to 915 participants in the AIDS Linke...
#1Gregory D KirkH-Index: 48
#2Hemali MehtaH-Index: 54
Last. David L. ThomasH-Index: 89
view all 8 authors...
It has been postulated that HIV infection accelerates hepatitis C virus (HCV)–related liver disease. This cohort study followed persons with HCV infection prospectively to compare the progression o...
#1Bohdan Nosyk (SFU: Simon Fraser University)H-Index: 26
#2Xiao Zang (SFU: Simon Fraser University)H-Index: 3
Last. Matthew R. Golden (UW: University of Washington)H-Index: 41
view all 20 authors...
Summary Background The HIV epidemic in the USA is a collection of diverse local microepidemics. We aimed to identify optimal combination implementation strategies of evidence-based interventions to reach 90% reduction of incidence in 10 years, in six US cities that comprise 24·1% of people living with HIV in the USA. Methods In this economic modelling study, we used a dynamic HIV transmission model calibrated with the best available evidence on epidemiological and structural conditions for six U...
1 CitationsSource