Darrel P. Francis
National Institutes of Health
CardiologyHeart failureDiabetes mellitusMedicineBlood pressure
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Publications 698
#1Yousif Ahmad (NIH: National Institutes of Health)H-Index: 12
#2James P. Howard (NIH: National Institutes of Health)H-Index: 15
Last. Manish Parikh (CUMC: Columbia University Medical Center)H-Index: 23
view all 17 authors...
Background For patients with ST‐segment–elevation myocardial infarction (STEMI) and multivessel coronary artery disease, the optimal treatment of the non‐infarct‐related artery has been controversi...
#1M.F. Piepoli (University of Parma)H-Index: 8
#2Piotr Ponikowski (Wrocław Medical University)H-Index: 105
Last. Andrew J.S. Coats (Monash University)H-Index: 113
view all 5 authors...
#1Takayuki WarisawaH-Index: 4
#2Christopher CookH-Index: 13
Last. Masafumi Nakayama (Waseda University)H-Index: 4
view all 27 authors...
Abstract Objectives The aim of this study was to assess the long-term clinical outcomes of patients with left main coronary artery (LM) stenosis in whom treatment strategy was based on the instantaneous wave-free ratio (iFR). Background The overall safety of iFR to guide revascularization decision making in patients with stable coronary artery disease has been established. However, no study has examined the safety of deferral of revascularization of LM disease on the basis of iFR. Methods This m...
1 CitationsSource
#1Patrik Bachtiger (NIH: National Institutes of Health)H-Index: 1
#2Carla M. Plymen (Imperial College Healthcare)H-Index: 3
Last. Nicholas S. Peters (Imperial College Healthcare)H-Index: 22
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A higher proportion of patients with heart failure have benefitted from a wide and expanding variety of sensor-enabled implantable devices than any other patient group. These patients can now also take advantage of the ever-increasing availability and affordability of consumer electronics. Wearable, on- and near-body sensor technologies, much like implantable devices, generate massive amounts of data. The connectivity of all these devices has created opportunities for pooling data from multiple ...
1 CitationsSource
#1Oliver J. Ziff (UCL: University College London)H-Index: 9
#2Monica Samra (UCL: University College London)H-Index: 1
Last. Dipak Kotecha (Monash University)H-Index: 28
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BACKGROUND: Beta-blockers are widely used for many cardiovascular conditions; however, their efficacy in contemporary clinical practice remains uncertain. METHODS: We performed a prospectively designed, umbrella review of meta-analyses of randomised controlled trials (RCTs) investigating the evidence of beta-blockers in the contemporary management of coronary artery disease (CAD), heart failure (HF), patients undergoing surgery or hypertension (registration: PROSPERO CRD42016038375). We searched...
#1Takayuki Warisawa (Imperial College London)H-Index: 2
#1Takayuki Warisawa (Imperial College London)H-Index: 4
Last. Hitoshi MatsuoH-Index: 26
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Abstract Background Identifying the individual hemodynamic significance of tandem coronary artery lesions can be complicated by the crosstalk phenomenon which occurs between serial stenoses under hyperemic conditions. Physiological assessments performed under resting conditions are considered to be, theoretically, less affected by the hemodynamic interaction between serial coronary stenoses. The purpose of this study was to assess whether pressure-wire (PW) pullback measurements at rest and duri...
#1Yousif Ahmad (Imperial College London)H-Index: 6
#1Yousif Ahmad (Imperial College London)H-Index: 12
Last. Darrel P. Francis (Imperial College London)H-Index: 71
view all 3 authors...
#1Amit Kaura (Imperial College Healthcare)H-Index: 1
#2Ahran D. Arnold (Imperial College Healthcare)
Last. Keith M. Channon (University of Oxford)H-Index: 78
view all 26 authors...
Background Patients presenting with atrial fibrillation (AF) often undergo a blood test to measure troponin, but interpretation of the result is impeded by uncertainty about its clinical importance...
#1Neda Azarmehr (University of Lincoln)H-Index: 1
#1Neda Azarmehr (University of Lincoln)
Last. Massoud Zolgharni (NIH: National Institutes of Health)H-Index: 9
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Speckle tracking is the most prominent technique used to estimate the regional movement of the heart based on echocardiograms. In this study, we propose an optimised-based block matching algorithm to perform speckle tracking iteratively. The proposed technique was evaluated using a publicly available synthetic echocardiographic dataset with known ground-truth from several major vendors and for healthy/ischaemic cases. The results were compared with the results from the classic (standard) two-dim...
#1James P. Howard (NIH: National Institutes of Health)H-Index: 1
#1James P. HowardH-Index: 1
Last. Darrel P. FrancisH-Index: 1
view all 16 authors...
Echocardiography is the commonest medical ultrasound examination, but automated interpretation is challenging and hinges on correct recognition of the ‘view’ (imaging plane and orientation). Current state-of-the-art methods for identifying the view computationally involve 2-dimensional convolutional neural networks (CNNs), but these merely classify individual frames of a video in isolation, and ignore information describing the movement of structures throughout the cardiac cycle. Here we explore...