Marcus Richards
University College London
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Publications 402
#1Ellen J Thompson (UCL: University College London)
#2Marcus Richards (UCL: University College London)H-Index: 53
Last. Praveetha Patalay (UCL: University College London)H-Index: 16
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Objective: To investigate whether the associations between adolescent externalising and internalising mental health difficulties and mid-life health and social outcomes are changing across cohorts. Methods: Data from 31,349 participants followed as part of two prospective national birth cohort studies: 1958 National Child Development Study (n=16091) and the 1970 British Cohort Study (n=15258). Adolescent mental health at age 16 years was assessed using the Rutter scales and operationalised as bo...
BACKGROUND Affective symptoms are associated with cognition in mid-life and later life. However, the role of cardiometabolic risk in this association has not been previously examined. AIMS To investigate how cardiometabolic risk contributes to associations between affective symptoms and mid-life cognition. METHOD Data were used from the National Child Development Study (NCDS), a sample of people born in Britain during one week in 1958. Measures of immediate and delayed memory, verbal fluency and...
#1Hannah E. Jongsma (UCL: University College London)H-Index: 4
#2Vanessa Moulton (UCL: University College London)
Last. Praveetha Patalay (UCL: University College London)H-Index: 16
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Background Life-course and cross-cohort investigations of psychological distress are limited by differences in measures used across time within- and between- cohorts. Aims We aimed to examine adulthood distribution of symptoms and cross-cohort trends by test-equating mental health measures administered in the 1946, 1958 and 1970 British birth cohorts. Methods We used data from the above three birth cohorts (N=32,242) and an independently recruited calibration sample (n=5,800) where all measures ...
#1Sarah Buchanan (UCL: University College London)H-Index: 2
#2Thomas D. Parker (UCL: University College London)H-Index: 7
Last. Jennifer M. Nicholas (Lond: University of London)H-Index: 22
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OBJECTIVE To explore the value of olfactory identification deficits as a predictor of cerebral β-amyloid status and other markers of brain health in cognitively normal adults aged ~ 70 years. METHODS Cross-sectional observational cohort study. 389 largely healthy and cognitively normal older adults were recruited from the MRC National Survey of Health and Development (1946 British Birth cohort) and investigated for olfactory identification deficits, as measured by the University of Pennsylvania ...
1 CitationsSource
#1Thanasis G. Tektonidis (Oxford Brookes University)H-Index: 4
#2Shelly Coe (Oxford Brookes University)H-Index: 5
Last. Helen Dawes (Oxford Brookes University)H-Index: 31
view all 10 authors...
#1Amber John (University of Sussex)H-Index: 3
#2Jennifer Rusted (University of Sussex)H-Index: 33
Last. Darya Gaysina (University of Sussex)H-Index: 14
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Objectives: There is an association between affective symptoms and cognition. However, the direction of this association remains unclear. This study aimed to test bidirectional relationships betwee...
#1Jodie Lord ('KCL': King's College London)
#2Bradley Jermy ('KCL': King's College London)
Last. Petra Proitsi ('KCL': King's College London)H-Index: 10
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There are currently no disease modifying treatments for Alzheimers Disease (AD). Epidemiological studies have highlighted blood metabolites as potential biomarkers, but possible confounding and reverse causation prevent causal conclusions. Here, we investigated whether nineteen metabolites previously associated with midlife cognitive function, are on the causal pathway to AD. Summary statistics from the largest Genome-Wide Association Studies (GWAS) for AD and for metabolites were used to perfor...
#1Lisa Harber-AschanH-Index: 2
#2Jayati Das-MunshiH-Index: 13
Last. Robert D. StewartH-Index: 28
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#1Thanasis G. Tektonidis (Oxford Brookes University)H-Index: 4
Last. Helen Dawes (Oxford Brookes University)H-Index: 31
view all 10 authors...
Healthy diet has been linked to better age-related functioning, but evidence on the relationship of diet quality in late midlife and measures of physical capability in later life is limited. Research on potential sex differences in this relationship is scarce. The aim was to investigate the prospective association between overall diet quality, as assessed by the Healthy Eating Index-2015 (HEI-2015) at 60-64 years and measures of walking speed 7 years later, among men and women from the Insight 4...
#2Martin Knapp (LSE: London School of Economics and Political Science)H-Index: 89
Last. Martin N. Rossor (NIH: National Institutes of Health)H-Index: 115
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WHAT IS KNOWN AND OBJECTIVE: Polypharmacy is common, and many medications have cognitive side effects. Such effects can be transient and subside when the drug in question is discontinued or can be long-lasting with effects present for years afterwards. Although formal assessment of cognition is feasible and often undertaken in neuropsychiatric trials, these effects are usually neglected in the evaluation of any non-neuropsychiatric health intervention. Medication effects can be assessed within a...