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Ana Paula Vieira Colombo
Federal University of Rio de Janeiro
DentistryChronic periodontitisPeriodontitisMedicineMicrobiology
82Publications
31H-index
2,792Citations
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Publications 82
Newest
#1Fátima Aparecida Rocha Resende Hartenbach (UFRJ: Federal University of Rio de Janeiro)H-Index: 2
#2Erika Velasquez (UFRJ: Federal University of Rio de Janeiro)H-Index: 3
Last. Ana Paula Vieira Colombo (UFRJ: Federal University of Rio de Janeiro)H-Index: 31
view all 6 authors...
Abstract Periodontitis is a chronic inflammatory disease resulting from a dysbiosis of the dental biofilm and a dysregulated host response in susceptible individuals. It is characterized by periodontal attachment destruction, bone resorption and eventual tooth loss. Salivary biomarkers have been sought to predict and prevent periodontitis. This comparative study analyzed the salivary proteome of individuals with chronic periodontitis (CP) and periodontal health (pH) and correlated specific prote...
2 CitationsSource
#1Natália L. C. Silva (UFRJ: Federal University of Rio de Janeiro)H-Index: 1
#2Nadia Alice Vieira da Motta (Federal Fluminense University)H-Index: 4
Last. Jorge L. M. Tributino (UFRJ: Federal University of Rio de Janeiro)H-Index: 6
view all 10 authors...
BACKGROUND AND OBJECTIVES: Periodontitis can corroborate with development and progression of atherosclerosis and a possible bidirectional interaction between both pathologies has been hypothesized. The aim of this work was to study the interactions between diet-induced hypercholesterolemia and ligature-induced periodontitis in Wistar rats submitted to both conditions. MATERIAL AND METHODS: Animals were divided into four experimental groups: C (control: standard diet without periodontitis), Perio...
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#1Talita Gomes Baeta Lourenςo (UFRJ: Federal University of Rio de Janeiro)H-Index: 1
#2Sarah J. Spencer (MIT: Massachusetts Institute of Technology)H-Index: 8
Last. Ana Paula Vieira Colombo (UFRJ: Federal University of Rio de Janeiro)H-Index: 31
view all 4 authors...
Background: This exploratory study aimed to characterize the gut microbiome of individuals with different periodontal conditions, and correlate it with periodontal inflammation and tissue destruction.Methods: Stool samples were obtained from individuals presenting periodontal health (PH = 7), gingivitis (G = 14) and chronic periodontitis (CP = 23). The intestinal microbiome composition was determined by Illumina MiSeq sequencing.Results: A lower alpha-diversity in the gut microbiome of individua...
11 CitationsSource
Last. Eric J. AlmH-Index: 60
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#1Rachel Garcia de Miranda (UFRJ: Federal University of Rio de Janeiro)H-Index: 3
#2Ana Paula Vieira Colombo (UFRJ: Federal University of Rio de Janeiro)H-Index: 31
Introduction This short-term randomized controlled trial evaluated the effectiveness of photodynamic therapy (PDT) on clinical success (periapical healing) and on the microbiota of primary endodontic infections.
11 CitationsSource
#1Mariana Vm Ferreira (UFRJ: Federal University of Rio de Janeiro)
#2Édila Ff Cavalcanti (UFRJ: Federal University of Rio de Janeiro)
Last. Ana Paula Vieira Colombo (UFRJ: Federal University of Rio de Janeiro)H-Index: 31
view all 6 authors...
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#1Carina M. Silva-Boghossian (UFRJ: Federal University of Rio de Janeiro)H-Index: 13
#2Paola C. Cesário (UFRJ: Federal University of Rio de Janeiro)H-Index: 1
Last. Ana Paula Vieira Colombo (UFRJ: Federal University of Rio de Janeiro)H-Index: 31
view all 4 authors...
BACKGROUND: This study compared the composition of subgingival microbiota between obese and non-obese women with or without periodontal disease. METHODS: Full-mouth periodontal clinical assessments were carried out in 76 obese women (17 periodontally healthy and 59 with periodontal disease), and 34 non-obese women (12 periodontally healthy, 22 with periodontal disease). Subgingival biofilm samples were individually obtained from seven sites of each individual, and the prevalence and counts of 40...
4 CitationsSource
#1Fátima Aparecida Rocha Resende Hartenbach (UFRJ: Federal University of Rio de Janeiro)H-Index: 2
#2Carina M. Silva-Boghossian (UFRJ: Federal University of Rio de Janeiro)H-Index: 13
Last. Ana Paula Vieira Colombo (UFRJ: Federal University of Rio de Janeiro)H-Index: 31
view all 3 authors...
Abstract Objective In this study, we hypothesized that in the absence of oral hygiene, re-growth of the climax microbial communities of supra and subgingival biofilm happens in a faster and more intense fashion in individuals with chronic periodontitis (CP) compared to periodontally healthy controls (PH). Design Thirty patients (PH = 15 and CP = 15) received professional supragingival prophylaxis, and were asked to refrain from oral hygiene for 7 days. Supra and subgingival biofilm samples and G...
2 CitationsSource
#1Ana Paula Vieira Colombo (UFRJ: Federal University of Rio de Janeiro)H-Index: 31
#2Bruce J. Paster (The Forsyth Institute)H-Index: 73
Last. Philip Stashenko (The Forsyth Institute)H-Index: 54
view all 10 authors...
Background: Non-human primates appear to represent the most faithful model of human disease, but to date the oral microbiome in macaques has not been fully characterized using next-generation seque...
3 CitationsSource
#1Laís Christina Pontes Espíndola (UFRJ: Federal University of Rio de Janeiro)H-Index: 1
#2Ana Paula Vieira Colombo (UFRJ: Federal University of Rio de Janeiro)H-Index: 31
To test the adjunctive effect of 0.1% sodium hypochlorite (NaOCl) mouthwash combined to full-mouth ultrasonic debridement (FMUD) on reducing supragingival plaque, gingival inflammation, and microbial pathogens. In this 6-month double-blinded randomized clinical trial, individuals with gingivitis were assigned to test (n = 16) or placebo group (n = 16) and received FMUD followed by rinsing with 0.1% NaOCl (test) or distilled water (placebo), respectively, twice a day for 1 month. Full-mouth perio...
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