Koichi Sato
Juntendo University
Publications 123
#1Kiichi Sugimoto (JHUSOM: Johns Hopkins University School of Medicine)
#2Tomoaki Ito (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 1
Last.Hitoshi KataiH-Index: 42
view all 17 authors...
Background Although primary (PGC) and remnant gastric cancers (RGC) both originate from the same gastrointestinal organ, they have very distinct clinicopathological behaviors. We hypothesized that there would be distinct differences in DNA methylation patterns that would occur during carcinogenesis of RGC and PGC, and that the differences in methylation patterns may help identify the primary factor contributing to chronic inflammation in patients with RGC.
#1Kiichi Sugimoto (Juntendo University)
#2Tomoaki Ito (Juntendo University)H-Index: 1
Last.Edward Gabrielson (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 64
view all 8 authors...
Abstract Background Esophageal squamous cell carcinoma (ESCC) is common in East Asia and also is often deadly. We sought to determine whether measuring the discoidin domain receptor-1 (DDR1)—both total and phosphorylated proteins—could improve our ability to predict recurrence in ESCC. Materials and Methods Total DDR1 and phosphorylated DDR1 (pDDR1) were measured using semiquantitative immunohistochemistry in a cohort of 60 patients with ESCC. Association between these immunohistochemical measur...
#1Satoshi TokudaH-Index: 1
#2Shunsuke SakurabaH-Index: 1
Last.Koichi SatoH-Index: 11
view all 7 authors...
Introduction. There are many possible causes of an abdominal visceral aneurysm, including the obstruction of the celiac artery by the median arcuate ligament (MAL). We report two cases of an aneurysm of the pancreaticoduodenal artery due to MAL syndrome that we treated surgically. Case Presentation. Case 1: a 66-year-old Japanese woman was diagnosed with a rupture of an aneurysm of the inferior pancreaticoduodenal artery. Because of the difficulty of endovascular therapy, we performed an emergen...
#1Toshiaki Iba (Juntendo University)H-Index: 26
#2Makoto Arakawa (Juntendo University)H-Index: 2
Last.Jerrold H. Levy (Duke University)H-Index: 63
view all 7 authors...
For success in clinical trials, eliminating inclusion of patients with irreversible recovery is important. The purpose of this study was to identify the patient population who do not survive for more than 3 days. A total of 449 patients with sepsis suspected of having disseminated intravascular coagulation (DIC) and treated with antithrombin were examined. The patient characteristics, baseline sequential organ failure assessment (SOFA) score, DIC score, and hemostatic markers were retrospectivel...
#1Toshiaki Iba (Juntendo University)H-Index: 26
#2Jerrold H. Levy (Duke University)H-Index: 63
Last.Isao Nagaoka (Juntendo University)H-Index: 41
view all 7 authors...
Abstract Introduction Injury and loss of the endothelial glycocalyx occur during the early phase of sepsis. We previously showed that antithrombin has a protective effect on this structure in vitro . Here, we investigated the possible protective effects of antithrombin in an animal model of sepsis. Methods Wistar rats were injected with endotoxin, and circulating levels of syndecan-1, hyaluronan, albumin, lactate and other biomarkers were measured in an antithrombin-treated group and an untreate...
#1Toshiaki Iba (Juntendo University)H-Index: 26
#2Makoto Arakawa (Juntendo University)H-Index: 2
Last.Koichi Sato (Juntendo University)H-Index: 11
view all 7 authors...
Disseminated intravascular coagulation (DIC) in patients with sepsis represents a critical condition. Thus, a simple and rapid diagnosis is required. The purpose of this study was to compare the performances of a recently developed Sepsis-Induced Coagulopathy (SIC) with the Japanese Association for Acute Medicine (JAAM) DIC. Four hundred nine patients with sepsis having coagulopathy and antithrombin activity of less than 70% and treated with antithrombin were retrospectively analyzed, and the SI...
#1Tomoaki Ito (Juntendo University)H-Index: 6
#2Hiroshi Maekawa (Juntendo University)H-Index: 11
Last.Koichi Sato (Juntendo University)H-Index: 11
view all 7 authors...
Background: The management of gastric cancer patients who received gastrectomy and/or postoperative chemotherapy is of high importance. However, the safety and efficacy of chemotherapy in hemodialysis patients have not been established. In this study, we report 6 cases of hemodialysis patients who underwent gastrectomy for gastric cancer. Case Presentation: The presented cases included 5 men and 1 woman, with a mean age of 66.3 years (range, 59–74 years). All patients underwent standard laparoto...
#1Hisaki Kato (Juntendo University)
#2Shinya Munakata (Juntendo University)H-Index: 2
Last.Hajime Orita (Juntendo University)H-Index: 11
view all 13 authors...
Objectives To investigate the effect of left colonic artery (LCA) preservation on laparoscopic sigmoidectomy outcomes