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Tracy Merlin
University of Adelaide
72Publications
18H-index
1,347Citations
Publications 80
Newest
#1Mah Laka (University of Adelaide)
#2Adriana Milazzo (University of Adelaide)H-Index: 5
Last.Tracy Merlin (University of Adelaide)H-Index: 18
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#1Nadine T. Hillock (University of Adelaide)
#2Jonathan Karnon (Flinders University)H-Index: 29
Last.Tracy Merlin (University of Adelaide)H-Index: 18
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Abstract Objective To identify and estimate the usage of unregistered antimicrobial drugs in Australian clinical practice. Methods A descriptive pharmaco-epidemiological study, utilising three data sources: analysis of Special Access Scheme (SAS) applications for unregistered antimicrobials included in clinical guidelines over a five year period, analysis of antimicrobials dispensed from South Australian public hospital pharmacy departments over a two year period and analysis of National Antimic...
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#1Mah Laka (University of Adelaide)
#2Adriana Milazzo (University of Adelaide)H-Index: 5
Last.Tracy Merlin (University of Adelaide)H-Index: 18
view all 3 authors...
Excessive and unnecessary antibiotic prescriptions have resulted in an increased prevalence of drug-resistant bacteria. Our findings indicate that electronic decision support tools are effective in promoting evidence-based optimal antibiotic management by improving clinical and economic outcomes. Understanding the challenges with implementation at the individual, organizational and policy level is critical in determining the sustainability of decision support tools for different healthcare setti...
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#1Sharon J. M. Kessels (University of Adelaide)H-Index: 2
#2Drew Carter (University of Adelaide)H-Index: 7
Last.Tracy Merlin (University of Adelaide)H-Index: 18
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We aimed to assess the clinical value of prenatal testing for cystic fibrosis (CF) and whether ethical considerations would affect endpoint selection. To determine effectiveness, we conducted a systematic literature review whose protocol outlined search strategies across eight databases, study inclusion criteria, and prespecified literature screening, data extraction, and synthesis processes. We conducted a scoping search on ethical considerations. The genetic test showed good diagnostic perform...
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#1Drew Carter (University of Adelaide)H-Index: 7
#2Tracy Merlin (University of Adelaide)H-Index: 18
Last.David Hunter (Flinders University)H-Index: 9
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Abstract Sometimes a government or other payer is called on to fund a new health technology even when the evidence leaves a lot of uncertainty. One option is for the payer to provisionally fund the technology and reduce uncertainty by developing evidence. This is called coverage with evidence development (CED). Only-in-research CED, when the payer funds the technology only for patients who participate in the evidence development, raises the sharpest ethical questions. Is the patient coerced or i...
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Objective Increasing antimicrobial resistance and a concurrent paucity of new antimicrobials marketed increases the risk that patients will develop infections resistant to currently available drugs. This study aimed to determine the range of clinical indications for which unregistered antimicrobials are prescribed at two tertiary hospitals in South Australia to identify any trends over a 2-year period. The effects of recent regulatory changes to the Special Access Scheme (SAS) were assessed. Met...
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