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Thomas A. Pearson
University of Florida
CardiologyDiseaseRisk factorDiabetes mellitusMedicine
393Publications
80H-index
37.7kCitations
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Publications 394
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#1Hui Hu (UF: University of Florida)H-Index: 12
#2Jinying Zhao (UF: University of Florida)H-Index: 21
Last. Thomas A. Pearson (UF: University of Florida)H-Index: 80
view all 6 authors...
Abstract It is widely recognized that exogenous factors play an important role in the development of hypertensive disorders of pregnancy (HDP). However, only a few external environmental factors have been studied, often separately, with no attempt to examine the totality of the external environment, or the external exposome. We conducted an external exposome-wide association study (ExWAS) using the Florida Vital Statistics Birth Records including 819,399 women with live births in 2010–2013. A to...
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#1Penny M. Kris-Etherton (PSU: Pennsylvania State University)H-Index: 95
#2Paul W. Stewart (UNC: University of North Carolina at Chapel Hill)H-Index: 38
Last. Rajasekhar Ramakrishnan (Columbia University)H-Index: 46
view all 15 authors...
BACKGROUND Factor VIIc, fibrinogen, and plasminogen activator inhibitor 1 (PAI-1) are cardiovascular disease (CVD) risk factors and are modulated, in part, by fat type and amount. OBJECTIVE We evaluated fat type and amount on the primary outcomes: factor VIIc, fibrinogen, and PAI-1. METHODS In the Dietary Effects on Lipoproteins and Thrombogenic Activity (DELTA) Trial, 2 controlled crossover feeding studies evaluated substituting carbohydrate or MUFAs for SFAs. Study 1: healthy participants (n =...
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#1Yi Zheng (UF: University of Florida)H-Index: 1
#2Zhaoyi Chen (UF: University of Florida)H-Index: 4
Last. Mattia Prosperi (UF: University of Florida)H-Index: 29
view all 6 authors...
Abstract Environment-wide association studies (EWAS) are an untargeted, agnostic, and hypothesis-generating approach to exploring environmental factors associated with health outcomes, akin to genome-wide association studies (GWAS). While design, methodology, and replicability standards for GWAS are established, EWAS pose many challenges. We systematically reviewed published literature on EWAS to categorize scope, impact, types of analytical approaches, and open challenges in designs and methodo...
1 CitationsSource
#1Hui Hu (UF: University of Florida)H-Index: 12
#2Jinying Zhao (UF: University of Florida)H-Index: 21
Last. Thomas A. Pearson (UF: University of Florida)H-Index: 80
view all 5 authors...
Source
#1Hui Hu (UF: University of Florida)H-Index: 12
#2Jiang Bian (UF: University of Florida)H-Index: 1
Last. Jinying Zhao (UF: University of Florida)H-Index: 21
view all 6 authors...
Source
#1Yi Zheng (UF: University of Florida)H-Index: 1
#2Jiang Bian (UF: University of Florida)H-Index: 1
Last. Hui Hu (UF: University of Florida)H-Index: 12
view all 6 authors...
Source
#1Daniel K. Onion (Dartmouth College)H-Index: 3
#2Roderick E. Prior (Memorial Hospital of South Bend)H-Index: 1
Last. Thomas A. Pearson (UF: University of Florida)H-Index: 80
view all 7 authors...
Importance It is unclear whether effective population-wide interventions that reduce risk factors and improve health result in sustained benefits to a community's health. If benefits do persist after a program is ended, interventions could be brief rather than maintained long term. Objective To measure mortality and smoking rates in a rural community over decades before, during, and after prevention program reductions. Design, Setting, and Participants This cross-sectional study compared smoking...
Source
#1Hui Hu (UF: University of Florida)H-Index: 12
#2Thomas A. Pearson (UF: University of Florida)H-Index: 80
Last. Linda B. Cottler (UF: University of Florida)H-Index: 49
view all 7 authors...
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#1John Michael Gaziano (Harvard University)H-Index: 116
#2Carlos BrotonsH-Index: 1
Last. Gianni TognoniH-Index: 93
view all 12 authors...
Summary Background The use of aspirin in the primary prevention of cardiovascular events remains controversial. We aimed to assess the efficacy and safety of aspirin versus placebo in patients with a moderate estimated risk of a first cardiovascular event. Methods ARRIVE is a randomised, double-blind, placebo-controlled, multicentre study done in seven countries. Eligible patients were aged 55 years (men) or 60 years (women) and older and had an average cardiovascular risk, deemed to be moderate...
112 CitationsSource
#1Matthew J. Gurka (UF: University of Florida)H-Index: 30
#2Stephanie L. Filipp (UF: University of Florida)H-Index: 6
Last. Mark D. DeBoer (UVA: University of Virginia)H-Index: 32
view all 4 authors...
Background Type 2 diabetes mellitus (T2DM) is considered a cardiovascular disease (CVD) risk equivalent, thereby linking assessment of cardiometabolic risk with that of CVD risk over time. Our goal...
2 CitationsSource
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