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Philip R. Holland
King's College London
Calcitonin gene-related peptideNeuroscienceMigraineAnesthesiaMedicine
72Publications
27H-index
2,540Citations
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Publications 76
Newest
#1Philip R. Holland ('KCL': King's College London)H-Index: 27
#2Paula Sureda-Gibert ('KCL': King's College London)
Last. Marta Vila-Pueyo ('KCL': King's College London)H-Index: 8
view all 3 authors...
Source
#1Christopher M. Holton ('KCL': King's College London)
#2Lauren C. Strother ('KCL': King's College London)H-Index: 2
Last. Philip R. Holland ('KCL': King's College London)H-Index: 27
view all 6 authors...
BACKGROUND AND PURPOSE: There is a major unmet need to develop new therapies for migraine. We have previously demonstrated the therapeutic potential of the acid-sensing ion channel (ASIC) blockade in migraine, via an ASIC1 mechanism. ASIC3 is expressed in the trigeminal ganglion and its response is potentiated by NO that can trigger migraine attacks in patients. Thus we sought to explore the potential therapeutic effect of ASIC3 blockade in migraine. EXPERIMENTAL APPROACH: To investigate this, w...
Source
#1Peter J. Goadsby ('KCL': King's College London)H-Index: 111
#2Philip R. Holland ('KCL': King's College London)H-Index: 27
1 CitationsSource
#1Jan Hoffmann ('KCL': King's College London)H-Index: 14
#2Philip R. Holland ('KCL': King's College London)H-Index: 27
1 CitationsSource
#1Andrea M. Harriott (Harvard University)H-Index: 9
#2Lauren C. Strother ('KCL': King's College London)H-Index: 2
Last. Philip R. Holland ('KCL': King's College London)H-Index: 27
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Background Migraine is a common debilitating condition whose main attributes are severe recurrent headaches with accompanying sensitivity to light and sound, nausea and vomiting. Migraine-related pain is a major cause of its accompanying disability and can encumber almost every aspect of daily life.
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#1Philip R. Holland ('KCL': King's College London)H-Index: 27
#2Chonlawan Saengjaroentham ('KCL': King's College London)H-Index: 1
Last. Marta Vila-Pueyo ('KCL': King's College London)H-Index: 8
view all 3 authors...
BackgroundMigraine is a severe debilitating disorder of the brain that is ranked as the sixth most disabling disorder globally, with respect to disability adjusted life years, and there remains a s...
2 CitationsSource
#1Marta Vila-PueyoH-Index: 8
#2Lauren C. StrotherH-Index: 2
Last. Philip R. HollandH-Index: 27
view all 5 authors...
5 CitationsSource
#1Simon Akerman (NYU: New York University)H-Index: 29
#2Nazia Karsan (University of Cambridge)H-Index: 6
Last. Peter J. Goadsby (University of Cambridge)H-Index: 111
view all 7 authors...
6 CitationsSource
#2Nazia KarsanH-Index: 6
Last. Peter J. GoadsbyH-Index: 111
view all 7 authors...
#1Philip R. Holland ('KCL': King's College London)H-Index: 27
#2Jan Hoffmann ('KCL': King's College London)H-Index: 14
Last. Peter J. Goadsby ('KCL': King's College London)H-Index: 111
view all 3 authors...
Source
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