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Dipender Gill
Imperial College London
40Publications
6H-index
129Citations
Publications 40
Newest
#1Raha PazokiH-Index: 14
#2Evangelos Evangelou (UoI: University of Ioannina)H-Index: 44
Last.Ioanna Tzoulaki (Imperial College London)H-Index: 47
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Urinary sodium and potassium excretion are associated with blood pressure (BP) and cardiovascular disease (CVD). The exact biological link between these traits is yet to be elucidated. Here, we identify 50 loci for sodium and 13 for potassium excretion in a large-scale genome-wide association study (GWAS) on urinary sodium and potassium excretion using data from 446,237 individuals of European descent from the UK Biobank study. We extensively interrogate the results using multiple analyses such ...
#1Dipender Gill (Imperial College London)H-Index: 6
#2Christopher F. Brewer (Royal Free Hospital)
Last.Abbas Dehghan (Imperial College London)H-Index: 62
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Background Systemic iron status has been implicated in atherosclerosis and thrombosis. The aim of this study was to investigate the effect of genetically determined iron status on carotid intima‐me...
#1Dipender Gill (Imperial College London)H-Index: 6
#2Nicole E. James (Imperial College London)
Last.Graeme J. Hankey (UWA: University of Western Australia)H-Index: 104
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#1Dipender Gill (Imperial College London)H-Index: 6
#2Marios K. Georgakis (LMU: Ludwig Maximilian University of Munich)H-Index: 2
Last.Rainer Malik (LMU: Ludwig Maximilian University of Munich)H-Index: 31
view all 14 authors...
Background: Drug effects can be investigated through natural variation in the genes for their protein targets. The present study aimed to use this approach to explore the potential side effects and...
#1Dipender Gill (Imperial College London)H-Index: 6
#2Beben Benyamin (UQ: University of Queensland)H-Index: 24
Last.Konstantinos K. Tsilidis (Imperial College London)H-Index: 18
view all 14 authors...
Background Iron is integral to many physiological processes, and variations in its levels, even within the normal range, can have implications for health. The objective of this study was to explore the broad clinical effects of varying iron status. Methods and findings Genome-wide association study (GWAS) summary data obtained from 48,972 European individuals (55% female) across 19 cohorts in the Genetics of Iron Status Consortium were used to identify 3 genetic variants (rs1800562 and rs1799945...
#1Elias Allara (University of Cambridge)H-Index: 8
#2G. Morani (UNIPV: University of Pavia)
Last.Dipender Gill (Imperial College London)H-Index: 6
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Aims: To systematically investigate causal relationships between circulating lipids and cardiovascular outcomes, using a Mendelian randomization approach. Methods and Results: In the primary analysis, we performed two-sample multivariable Mendelian randomization using data from participants of European ancestry. We also conducted univariable analyses using inverse-variance weighted and robust methods, and gene-specific analyses using variants that can be considered as proxies for specific lipid-...
#1Nikos Papadimitriou (IARC: International Agency for Research on Cancer)
#2Niki L Dimou (IARC: International Agency for Research on Cancer)H-Index: 1
Last.Kostantinos Tsilidis (Imperial College London)
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Background: The epidemiological literature reports inconsistent associations between consumption or circulating concentrations of micro-nutrients and breast cancer risk. We investigated associations between genetically determined concentrations of 11 micro-nutrients (beta-carotene, calcium, copper, folate, iron, magnesium, phosphorus, selenium, vitamin B6, vitamin B12 and zinc) and breast cancer risk using Mendelian randomization (MR). Materials and methods: A two-sample MR study was conducted u...
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