Match!
Yosuke Taniguchi
Kyushu University
OligonucleotideOrganic chemistryChemistryDNABiochemistry
84Publications
15H-index
691Citations
What is this?
Publications 87
Newest
Expansion of the triplex DNA forming sequence is required in the genomic targeting fields. Basically, the triplex DNA is formed by the interaction between the triplex-forming oligonucleotides and homo-purine region with the target duplex DNA. The presence of the base pair conversion sites is hampered by the stable triplex formations. To overcome this limitation, it is necessary to develop an artificial nucleic acid to recognize the base conversion sites, the CG and the TA base pairs. We now desc...
Source
#1Yasunobu Aoki (National Institute for Environmental Studies)H-Index: 19
#2Yosuke Taniguchi (Kyushu University)H-Index: 15
Last. Takehiko NohmiH-Index: 48
view all 10 authors...
Abstract Tumorigenesis induced by oxidative stress are recognized to be based on mutagenesis via indirect mechanism, but mechanism underlying the thresholds shown in the dose responses of oxidative-stress-induced tumorigenesis remains to be elucidated. To reveal this mechanism, we analyzed the dose responses of mutagenesis induced in gpt delta mice by the administration of potassium bromate, a typical oxidative-stress-generating agent. We supplied Nrf2-bearing mice and Nrf2-knockout (KO) mice wi...
Source
#1Yosuke Taniguchi (Kyushu University)H-Index: 15
#2Ikuko Sagara (Kyushu University)
Last. Shigeki Sasaki (Kyushu University)H-Index: 24
view all 5 authors...
Source
#1Yosuke Taniguchi (Kyushu University)H-Index: 15
#2Xiuming Cao (Kyushu University)
Last. Shigeki Sasaki (Kyushu University)H-Index: 24
view all 3 authors...
Abstract The efficient synthesis of the highly-deuterated thymidine-d9 by the glycosylation reaction between a deuterated nucleobase and deuterated sugar is described. It is also incorporated into the oligonucleotides using a DNA synthesizer. Using this approach, it is possible to make highly-deuterated oligonucleotides for biological studies and structural analyses.
Source
#1Ninticha Thavoncharoensub (MU: Mahidol University)
#2Kento Maruyama (Kyushu University)
Last. Yosuke Taniguchi (Kyushu University)H-Index: 15
view all 8 authors...
Abstract8-OxodGTP is generated by the reaction between dGTP and reactive oxygen species and a considered mutagenic nucleotide. It can be incorporated into the duplex DNA during replication processe...
Source
#1Kenji Kikuta (Kyushu University)H-Index: 1
#2Yosuke Taniguchi (Kyushu University)H-Index: 15
Last. Shigeki Sasaki (Kyushu University)H-Index: 24
view all 3 authors...
Source
#1Yosuke Taniguchi (Kyushu University)H-Index: 15
#2Lei Wang (Kyushu University)H-Index: 2
Last. Shigeki Sasaki (Kyushu University)H-Index: 24
view all 4 authors...
Source
#1Lei Wang (Kyushu University)H-Index: 2
#2Yosuke Taniguchi (Kyushu University)H-Index: 15
Last. Shigeki Sasaki (Kyushu University)H-Index: 24
view all 4 authors...
2 CitationsSource
#1Yosuke Taniguchi (Kyushu University)H-Index: 15
#2Mei Miyazaki (Kyushu University)
Last. Shigeki Sasaki (Kyushu University)H-Index: 24
view all 6 authors...
Source
Source
123456789