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Wande B. Pratt
Beth Israel Deaconess Medical Center
SurgeryPancreaticoduodenectomyPancreatic fistulaGeneral surgeryMedicine
35Publications
18H-index
1,695Citations
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Publications 34
Newest
#1Maxwell T. Trudeau (UPenn: University of Pennsylvania)H-Index: 1
#2Fabio Casciani (UPenn: University of Pennsylvania)
Last. Horacio J. Asbun (Mayo Clinic)H-Index: 36
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OBJECTIVE This study aims to present a full spectrum of individual patient presentations of pancreatic fistula risk, and to define the utility of mitigation strategies amongst some of the most prevalent, and vulnerable scenarios surgeons encounter. BACKGROUND The FRS has been utilized to identify technical strategies associated with reduced CR-POPF incidence across various risk strata. However, risk-stratification using the FRS has never been investigated with greater granularity. By deriving al...
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#1Gerald R. FortunaH-Index: 4
#2Joseph J. DuBoseH-Index: 41
Last. Ali AzizzadehH-Index: 29
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#1Payam Salehi (WashU: Washington University in St. Louis)H-Index: 1
#2Wande B. Pratt (WashU: Washington University in St. Louis)H-Index: 18
Last. Robert W. Thompson (WashU: Washington University in St. Louis)H-Index: 57
view all 5 authors...
Various anomalous muscles and fibrofascial structures have been described in relation to the anatomy of thoracic outlet syndrome. We describe two patients with a previously undescribed muscle anomaly, which originated laterally near the trapezius muscle, coursed across the supraclavicular space deep to the scalene fat pad, and attached obliquely to the superior undersurface of the medial clavicle, which we have termed the "supraclavius" muscle. The significance of the supraclavius muscle is unkn...
1 CitationsSource
#1Payam Salehi (WashU: Washington University in St. Louis)H-Index: 1
#2Wande B. Pratt (WashU: Washington University in St. Louis)H-Index: 18
Last. Robert W. Thompson (WashU: Washington University in St. Louis)H-Index: 57
view all 5 authors...
Source
#1Payam Salehi (WashU: Washington University in St. Louis)H-Index: 1
#2Wande B. Pratt (WashU: Washington University in St. Louis)H-Index: 18
Last. Luis A. Sanchez (WashU: Washington University in St. Louis)H-Index: 29
view all 3 authors...
Source
Apr 25, 2014 in NEBEC (Northeast Bioengineering Conference)
#1Nurazhani A. Raof (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 1
#2Wande B. Pratt (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 18
Last. Matthew D. PhaneufH-Index: 16
view all 7 authors...
Intimal hyperplasia (IH) remains one of the primary causes of prosthetic vascular graft failure. The goal of this study is to engineer a vascular graft material that has the ability to knock down genes associated with IH by local delivery of a select siRNA moiety to cells surrounding the implant. Thrombospondin-2 (TSP-2), previously shown to have increased expression during graft implantation, is a logical candidate for knock down. TSP-2 siRNA, alone and when complexed with the transfection reag...
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#1Benjamin C. Miller (UPenn: University of Pennsylvania)H-Index: 5
#2John D. Christein (UAB: University of Alabama at Birmingham)H-Index: 31
Last. Charles M. Vollmer (UPenn: University of Pennsylvania)H-Index: 27
view all 7 authors...
Background The Fistula Risk Score (FRS), a ten-point scale that relies on weighted influence of four variables, has been shown to effectively predict clinically relevant postoperative pancreatic fistula (CR-POPF) development and its consequences after pancreatoduodenectomy (PD). The proposed FRS demonstrated excellent predictive capacity; however, external validation of this tool would confirm its universal applicability.
86 CitationsSource
#1Benjamin C. Miller (UPenn: University of Pennsylvania)H-Index: 5
#2John D. Christein (UAB: University of Alabama at Birmingham)H-Index: 31
Last. Charles M. Vollmer (UPenn: University of Pennsylvania)H-Index: 27
view all 9 authors...
Abstract Background The Post‐operative Morbidity Index (PMI) is a quantitative utility measure of a complication burden created by severity weighting. The Fistula Risk Score (FRS) is a validated model that predicts whether a patient will develop a post‐operative pancreatic fistula (POPF). These novel tools might provide further discrimination of the ISGPF grading system. Methods From 2001 to 2012, 1021 pancreaticoduodenectomies were performed at four institutions. POPFs were categorized by ISGPF...
21 CitationsSource
Introduction Intimal hyperplasia represents a complex pathologic vascular response to injury. Our group previously revealed that TSP-2 was associated with this response, and demonstrated that intraluminal delivery of TSP-2 siRNA can suppress the intimal hyperplastic response in an animal model. Furthermore, we have shown that siRNA can be incorporated into prosthetic graft material using a dip-coating technique. We sought to determine whether this method could be employed for siRNA delivery in o...
#1Benjamin C. Miller (UPenn: University of Pennsylvania)H-Index: 5
#2John D. Christein (UAB: University of Alabama at Birmingham)H-Index: 31
Last. Charles M. Vollmer (UPenn: University of Pennsylvania)H-Index: 27
view all 7 authors...
Background The Fistula Risk Score (FRS), a ten-point scale that relies on weighted influence of four variables, has been shown to effectively predict clinically relevant postoperative pancreatic fistula (CR-POPF) development and its consequences after pancreatoduodenectomy (PD). The proposed FRS demonstrated excellent predictive capacity; however, external validation of this tool would confirm its universal applicability.
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