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Uma Sharma
All India Institute of Medical Sciences
In vivo magnetic resonance spectroscopyPathologyMagnetic resonance imagingBreast cancerMedicine
102Publications
22H-index
1,616Citations
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Publications 108
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#1Pramod Kumar (CDC: Centers for Disease Control and Prevention)
#2Rajesh PandeyH-Index: 18
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India first detected SARS-CoV-2, causal agent of COVID-19 in late January-2020, imported from Wuhan, China. March-2020 onwards; importation of cases from rest of the countries followed by seeding of local transmission triggered further outbreaks in India. We used ARTIC protocol based tiling amplicon sequencing of SARS-CoV-2 (n=104) from different states of India using a combination of MinION and MinIT from Oxford Nanopore Technology to understand introduction and local transmission. The analyses...
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#1Deepti Upadhyay (AIIMS: All India Institute of Medical Sciences)H-Index: 2
#2Alka Singh (AIIMS: All India Institute of Medical Sciences)H-Index: 4
Last. Uma Sharma (AIIMS: All India Institute of Medical Sciences)H-Index: 22
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: Celiac disease (CeD) is an autoimmune enteropathy caused by gluten intake in genetically predisposed individuals. We investigated the metabolism of CeD by metabolic profiling of intestinal mucosa, blood plasma and urine using NMR spectroscopy and multivariate analysis. The metabolic profile of the small intestinal mucosa was compared between patients with CeD (n = 64) and disease controls (DCs, n = 30). The blood plasma and urinary metabolomes of CeD patients were compared with healthy control...
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#1Sangeetha Gupta (Amity University)
#2Uma Sharma (AIIMS: All India Institute of Medical Sciences)H-Index: 22
Last. Yogendra Kumar Gupta (AIIMS: All India Institute of Medical Sciences)H-Index: 36
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OBJECTIVES: Stroke is a leading cause of death and disability worldwide with limited therapeutic interventions. The current study explored proton nuclear magnetic resonance spectroscopy ((1) H NMR)-based metabolomic approach to elucidate the effect of lercanidipine on neurometabolic alterations in transient model of ischaemic stroke in rats. METHODS: In the present investigation, male Wistar rats were subjected to middle cerebral artery occlusion (MCAo) for 2 h followed by reperfusion using intr...
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#1Mainak Dutta (BITS: Birla Institute of Technology and Science)H-Index: 10
#2Brajesh Singh (IIT-KGP: Indian Institute of Technology Kharagpur)H-Index: 3
Last. Swagata Dasgupta (IIT-KGP: Indian Institute of Technology Kharagpur)H-Index: 25
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#1Harlokesh Narayan Yadav (AIIMS: All India Institute of Medical Sciences)H-Index: 6
#2Uma Sharma (AIIMS: All India Institute of Medical Sciences)H-Index: 22
Last. Yogendra Kumar Gupta (AIIMS: All India Institute of Medical Sciences)H-Index: 36
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Mercury generates free radicals and oxidative stress which are associated with renal injury. Tribulus terrestris (TT), Boerhavia diffusa (BD), and Terminalia chebula (TC) have anti-inflammatory and antioxidant properties. Hydroalcoholic extract of combination of TT, BD and TC were evaluated against mercuric chloride induced nephrotoxicity. Rats (n = 6) were treated with combination of TT, BD and TC in three different doses (198, 300 and 600 mg/kg) of equal ratio of each drug and Combination per ...
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#1H. WasanH-Index: 1
#2Devendra SinghH-Index: 2
Last. K.H. ReetaH-Index: 13
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1 CitationsSource
#1Ashok Sharma (AIIMS: All India Institute of Medical Sciences)H-Index: 16
#2Uma Sharma (AIIMS: All India Institute of Medical Sciences)H-Index: 22
Last. Moganty R. Rajeswari (AIIMS: All India Institute of Medical Sciences)H-Index: 14
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AbstractSquamous cell carcinoma (SCC) of skin has no standard treatment regimen, resulting in recurrences/metastasis. Although, doxorubicin (Dox), an anthracycline antibiotic has demonstrated some ...
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#1Uma Sharma (AIIMS: All India Institute of Medical Sciences)H-Index: 22
#2Khushbu Agarwal (AIIMS: All India Institute of Medical Sciences)H-Index: 4
Last. Naranamangalam R. Jagannathan (AIIMS: All India Institute of Medical Sciences)H-Index: 22
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Abstract Purpose Dynamic contrast enhanced MRI (DCEMRI), diffusion weighted imaging (DWI) and in vivo proton (1H) magnetic resonance spectroscopy (MRS) provides functional and molecular nature of breast cancer. This study evaluates the potential of the combination of three MR parameters [curve kinetics, apparent diffusion coefficient (ADC) and total choline (tCho) concentration] determined from these techniques in increasing the sensitivity of breast cancer detection. Methods MR investigations w...
1 CitationsSource
#1Uma Sharma (AIIMS: All India Institute of Medical Sciences)H-Index: 22
#2Naranamangalam R. Jagannathan (AIIMS: All India Institute of Medical Sciences)H-Index: 22
Breast cancer is a significant health concern in females, worldwide. In vivo proton (1H) MR spectroscopy (MRS) has evolved as a non-invasive tool for diagnosis and for biochemical characterization ...
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