Jorge F. Topete-Reyes
Mexican Social Security Institute
EndocrinologyImmunologyDiabetic nephropathyBody mass indexMedicine
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Publications 5
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#1Luz E Chavarria-Buenrostro (University of Guadalajara)
#2Jorge Hernández-Bello (University of Guadalajara)H-Index: 4
Last. Margarita Montoya-Buelna (University of Guadalajara)H-Index: 4
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Chronic kidney disease (CKD) is characterized by accumulation of proinflammatory cytokines, mainly tumor necrosis factor alpha (TNF-α). Single nucleotide polymorphisms (SNPs) of TNFA gene, including -238 G/A and -308 G/A, have been associated with alteration in the soluble TNF-α (sTNF-α) expression. The aim was to investigate the association of -238 y -308 TNFA gene SNPs with sTNF-α levels in CKD patients. We included 150 CKD patients and 192 control subjects (CS). Both SNPs were genotyped with ...
8 Citations
#2Javier Soto-Vargas (Mexican Social Security Institute)H-Index: 1
Last. Mario Salazar-PáramoH-Index: 19
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The angiotensin (Ang)-converting enzyme (ACE) insertion/deletion (I/D) polymorphism determines Ang II levels, but its relationship with lupus nephritis (LN) in different populations is controversial.Objective: To describe the allelic and genotypic distribution of the I/D polymorphism in Mexican mestizos with LN and assess an association with histological classes.Methods: We included 24 patients with systemic lupus erythematosus (SLE) without nephropathy, 41 with LN, 144 healthy subjects, and 36 ...
4 CitationsSource