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Shuvo Roy
University of California, San Francisco
Materials scienceElectronic engineeringMicroelectromechanical systemsMembraneMedicine
205Publications
32H-index
4,630Citations
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Publications 192
Newest
#1Harold D. Love (VUMC: Vanderbilt University Medical Center)H-Index: 11
#2Rachel Evans (VUMC: Vanderbilt University Medical Center)H-Index: 1
Last. William H. Fissell (VUMC: Vanderbilt University Medical Center)H-Index: 27
view all 8 authors...
Patient-oriented applications of cell culture include cell therapy of organ failure like chronic renal failure. Clinical deployment of a cell-based device for arti fi cial renal replacement requires qualitative and quantitative fi delity of a cultured cell to its in vivo counterpart. Active speci fi c apicobasal ion transport reabsorbs 90-99% of the fi ltered load of salt and water in the kidney. In a bioengineered kidney, tubular transport concentrates wastes and eliminates the need for hemodia...
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#1Rebecca C. Gologorsky (UCSF: University of California, San Francisco)H-Index: 1
#2Shuvo Roy (UCSF: University of California, San Francisco)H-Index: 32
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Introduction Bioengineering an implantable artificial kidney (IAK) will require renal epithelial cells capable of reabsorption of salt and water. We used genome engineering to modify cells for improved Na+/H+ exchange and H2O reabsorption. The non-viral piggyBac transposon system enables genome engineering cells to stably overexpress one or more transgenes simultaneously.
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#1Nina Hojs (UCSF: University of California, San Francisco)H-Index: 1
#2William H. Fissell (VUMC: Vanderbilt University Medical Center)H-Index: 27
Last. Shuvo Roy (UCSF: University of California, San Francisco)H-Index: 32
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CKD is a worldwide health problem and the number of patients requiring kidney replacement therapy is rising. In the United States, most patients with ESKD rely on in-center hemodialysis, which is burdensome and does not provide the same long-term benefits as kidney transplantation. Intensive hemodialysis treatments have demonstrated improved clinical outcomes, but its wider adoption is limited by equipment complexity and patient apprehension. Ambulatory devices for hemodialysis offer the potenti...
1 CitationsSource
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#1Sam Mansfield (UCSC: University of California, Santa Cruz)H-Index: 1
Last. Shuvo Roy (UCSF: University of California, San Francisco)H-Index: 32
view all 6 authors...
The healthcare industry has placed significant effort on reducing pressure injuries as they often occur while patients are seeking treatment for an unrelated condition, lengthen the stay of the patient, impact treatment options, are extremely painful, and can result in death. Current work has shown that an increase in nursing care can reduce pressure injury occurrence, but increased nursing care is not sustainable. The Braden Scale is the current method of stratifying patients by risk of forming...
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#1William H. Fissell (VUMC: Vanderbilt University Medical Center)H-Index: 27
#2Shuvo Roy (UCSF: University of California, San Francisco)H-Index: 32
Kidney disease is one of the leading causes of death and its prevalence continues to increase worldwide. However, the pace at which new treatments have become available has been excruciatingly slow over the past 30 years. A new White House directive promises to focus the spotlight on accelerating innovations for patients with kidney disease.
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#1Colin Yee (UCSF: University of California, San Francisco)H-Index: 1
#2David McCoy (UCSF: University of California, San Francisco)H-Index: 23
Last. Steven W. Hetts (UCSF: University of California, San Francisco)H-Index: 27
view all 13 authors...
Image-guided endovascular chemofiltration with ionic endovascular devices placed nonocclusively in the hepatic venous outflow tract and inferior vena cava during hepatic artery doxorubicin infusion...
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#1Deepika N. Sarode (UCSF: University of California, San Francisco)
#2Shuvo Roy (UCSF: University of California, San Francisco)H-Index: 32
ABSTRACTIntroduction: Blood-recirculating medical devices, such as mechanical circulatory support (MCS), extracorporeal membrane oxygenators (ECMO), and hemodialyzers, are commonly used to treat or improve quality of life in patients with cardiac, pulmonary, and renal failure, respectively. As part of their regulatory approval, guidelines for thrombosis evaluation in pre-clinical development have been established. In vitro testing evaluates a device’s potential to produce thrombosis markers in s...
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#1D LoveHarold (VUMC: Vanderbilt University Medical Center)H-Index: 1
#2AoMingfang (VUMC: Vanderbilt University Medical Center)H-Index: 1
Last. H FissellWilliam (VUMC: Vanderbilt University Medical Center)H-Index: 1
view all 11 authors...
End-stage renal disease afflicts ∼750,000 Americans and claims >100,000 lives annually in the United States. Kidney transplantation is associated with longest survival and least cost but is limited...
2 CitationsSource
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