Abida Raza
Aga Khan University
Publications 40
#1Asad Zia (QAU: Quaid-i-Azam University)H-Index: 2
#2Muhammad Ali (QAU: Quaid-i-Azam University)H-Index: 20
Last.Abida RazaH-Index: 9
view all 6 authors...
Background Approximately 10 million people in Pakistan are infected with the hepatitis C virus (HCV). Most patients develop chronic hepatitis, with rare cases of spontaneous clearance. However, little is known about multidrug resistant viral variants in Pakistan.
#1Asad Zia (QAU: Quaid-i-Azam University)H-Index: 2
#2Sumra Wajid Abbasi (QAU: Quaid-i-Azam University)H-Index: 4
Last.Abida RazaH-Index: 9
view all 5 authors...
Abstract The nonstructural protein 3 (NS3) helicase of HCV is believed to be a plausible target for the identification and designing of potent antiviral drugs. NS3 protein is involved in a positive sense single-stranded viral replication as well as it also cleaves viral poly protein into diverse mature proteins at different time spans. Structural exploration of NS3 revealed that HCV helicase could also act as translocase. In order to identify potential inhibitors for HCV-3a, the current study ha...
#1Farhad Ullah (UoP: University of Peshawar)H-Index: 2
#2Zafar Iqbal (UoP: University of Peshawar)H-Index: 48
Last.Muhammad Hassan (UoP: University of Peshawar)H-Index: 6
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Methotrexate (MTX) is an anticancer drug while metoclopramide (MCP) is an antiemetic agent. Both the drugs are commonly coprescribed to avoid the emesis caused by anticancer drug. In this study, a novel, rapid, sensitive, and cost-effective reverse-phase high-performance liquid chromatography method was developed and validated for simultaneous determination of the methotrexate and metoclopramide in biological and pharmaceutical samples using sparfloxacin as internal standard. The analytes were s...
#1Awan UaH-Index: 4
#2Shaukat Ali (University of Azad Jammu and Kashmir)H-Index: 4
Last.Abida RazaH-Index: 9
view all 7 authors...
Gold nanorods (GNRs) are ideal choice in biomedical research due to their amenability of synthesis, tunable plasmonic properties, less toxicity and ease of detection but their diverse biological applications necessitate stable structure. Despite two decades' efforts made towards reproducible anisotropic structures synthesis, still the kinetic control during GNRs growth has not been achieved. This study is an attempt to apprehend thermodynamic and kinetic parameters for synthesising mono-disperse...
Objectives: The present study aimed to examine the impact of rapid virological response (RVR) and early virological response (EVR) on sustained virological respon
#1Majid Mahmood (Pir Mehr Ali Shah Arid Agriculture University)H-Index: 2
#2Muhammad Asim Anwar (Pakistan Atomic Energy Commission)H-Index: 1
Last.Abida RazaH-Index: 9
view all 5 authors...
Background Hepatitis B virus (HBV) genotype and its role in disease progression and patients’ response to antiviral treatment, is not well studied in Pakistan. This comprehensive study was aimed to determine the distribution of HBV genotypes in Pakistan and their possible association with phases of HBV infection.