Kate D. Fitzgerald
University of Michigan
Publications 86
#1Katie L. Burkhouse (UIC: University of Illinois at Chicago)H-Index: 11
#2Jagan Jimmy (UIC: University of Illinois at Chicago)
Last.K. Luan Phan (UIC: University of Illinois at Chicago)
view all 9 authors...
Structural variations of neural regions implicated in fear responses have been well documented in the pathophysiology of anxiety and may play an important role in treatment response. We examined whether gray matter volume of three neural regions supporting fear and avoidance responses [bilateral amygdala, nucleus accumbens (NAcc), and ventromedial prefrontal cortex (PFC)] predicted cognitive-behavioral therapy (CBT) and selective serotonin reuptake inhibitor (SSRI) treatment outcome in two indep...
#1Christie L Burton (Hospital for Sick Children)H-Index: 1
#2Mathieu Lemire (Hospital for Sick Children)
Last.Paul D. Arnold (U of C: University of Calgary)H-Index: 8
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This study examined the genetic correlates of obsessive-compulsive (OC) traits and their shared genetic risks with obsessive-compulsive disorder (OCD). We conducted genome-wide association analyses on OC traits in 5018 unrelated Caucasian children and adolescents. Overall OC traits and trait dimensions (e.g., cleaning/contamination) were measured with the Toronto Obsessive-Compulsive scale (TOCS). One locus tagged by rs7856850 in an intron of PTPRD (protein tyrosine phosphatase delta;) was assoc...
#1Ka I. Ip (UM: University of Michigan)H-Index: 4
#2Yanni Liu (UM: University of Michigan)H-Index: 13
Last.Kate D. Fitzgerald (UM: University of Michigan)H-Index: 23
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Abstract The error-related negativity (ERN) is a neurophysiologic response to errors that associates with anxiety. Despite the potential relevance of the ERN for understanding mechanisms of early anxiety problems in the developing brain, the relation between ERN and anxious symptoms in young children remains poorly understood. Emerging evidence suggests that ERN-anxiety associations could vary by developmental stage, but this work requires replication and consideration of gender effects, given e...
Mood and anxiety disorders affect 20–30 percent of school-age children, contributing to academic failure, substance abuse, and adult psychopathology, with immense social and economic impact. These disorders are treatable, but only a fraction of students in need have access to evidence-based treatment practices (EBPs). Access could be substantially increased if school professionals were trained to identify students at risk and deliver EBPs in the context of school-based support services. However,...
#2Daan van RooijH-Index: 12
Last.Odile A. van den HeuvelH-Index: 26
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ABSTRACT Objective Attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and obsessive-compulsive disorder (OCD) are common neurodevelopmental disorders that frequently co-occur. We aimed to directly compare all three disorders. The ENIGMA consortium is ideally positioned to investigate structural brain alterations across these disorders. Methods Structural T1-weighted whole-brain MRI of controls (n=5,827) and patients with ADHD (n=2,271), ASD (n=1,777), and OCD (n=2,3...
#1Luke Norman (UM: University of Michigan)H-Index: 9
#2Stephan F. Taylor (UM: University of Michigan)H-Index: 43
Last.Kate D. Fitzgerald (UM: University of Michigan)H-Index: 23
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Abstract Background Error processing and inhibitory control enable the adjustment of behaviors to meet task demands. Functional magnetic resonance imaging studies report brain activation abnormalities in patients with obsessive-compulsive disorder (OCD) during both processes. However, conclusions are limited by inconsistencies in the literature and small sample sizes. Therefore, the aim here was to perform a meta-analysis of the existing literature using unthresholded statistical maps from previ...
5 CitationsSource
#1Luke NormanH-Index: 9
#2Stephan F. TaylorH-Index: 43
Last.Kate D. FitzgeraldH-Index: 23
view all 21 authors...
#1Luke NormanH-Index: 9
#2Mike AngstadtH-Index: 34
Last.Stephan F. TaylorH-Index: 43
view all 7 authors...
#1Xiangzhen Kong (MPG: Max Planck Society)H-Index: 10
#2Premika S.W. Boedhoe (VU: VU University Amsterdam)H-Index: 6
Last.Clyde Francks (MPG: Max Planck Society)H-Index: 42
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Background: Lateralized dysfunction has been suggested in obsessive-compulsive disorder (OCD). However, it is currently unclear whether OCD is characterized by abnormal patterns of brain structural asymmetry. Here we carried out what is by far the largest study of brain structural asymmetry in OCD. Methods: We studied a collection of 16 pediatric datasets (501 patients with OCD and 439 healthy control subjects), as well as 30 adult datasets (1777 patients and 1654 control subjects) from the OCD ...
4 CitationsSource