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Baoshan Wang
Hebei Medical University
Molecular biologyNitric oxide synthaseIntermittent hypoxiaCancer researchBiology
8Publications
4H-index
54Citations
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Publications 9
Newest
#1Lili Lan (Hebei Medical University)
#2Huan Cao (Hebei Medical University)H-Index: 2
Last. Baoshan Wang (Hebei Medical University)H-Index: 4
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Abstract Background Long noncoding RNAs (lncRNAs) play crucial role in formation and progression of tumors. DNA methylation has become increasingly recognized as a frequent event of epigenetic alterations and one of the primary mechanisms of gene inactivation. The research aims to investigate the biofunction of a novel lncRNA in LSCC. Methods qRT-PCR, BGS, and MSP methods were employed to measure the relative expression level and methylation status of LINC00886. Additionally, we examined the eff...
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#1Xin Lv (Hebei Medical University)H-Index: 5
#2Kexin Wang (Hebei Medical University)H-Index: 1
Last. Baoshan Wang (Hebei Medical University)H-Index: 4
view all 7 authors...
1 CitationsSource
#1Weina Cui (Hebei Medical University)H-Index: 2
#2Wenxia Meng (Hebei Medical University)H-Index: 2
Last. Baoshan Wang (Hebei Medical University)H-Index: 4
view all 6 authors...
2 CitationsSource
#1Lei Zhao (Hebei University)H-Index: 2
#2Huan Cao (Hebei Medical University)H-Index: 2
Last. Baoshan Wang (Hebei Medical University)H-Index: 4
view all 7 authors...
Abstract In order to explore the differentially expressed long non-coding RNAs (lncRNAs) in laryngeal squamous cell carcinoma (LSCC), the GSE84957 lncRNA expression profile was included in the present study through data mining in the National Center for Biotechnology Information/Gene Expression Omnibus (NCBI/GEO). Then, the differentially expressed genes (DEGs) of LSCC (1646 lncRNAs and 2713 mRNAs, fold change ≥ 2, P ≤ 0.05) were identified from the GSE84957 dataset using bioinformatics analysis...
2 CitationsSource
#1Wenxia Meng (Hebei Medical University)H-Index: 2
#2Weina Cui (Hebei Medical University)H-Index: 2
Last. Baoshan Wang (Hebei Medical University)H-Index: 4
view all 6 authors...
Background Dysregulated long noncoding RNAs (lncRNAs) are involved in the development of tumor. Aberrant methylation is one of the most frequent epigenetic alterations that regulate the expression of genes. The aim of this study was to determine the expression and methylation status of ZNF667-AS1 and ZNF667, elucidate their biological function in the development of LSCC, and identify a cis-regulation of ZNF667-AS1 to ZNF667.
5 CitationsSource
#1Xin Lv (Hebei Medical University)H-Index: 5
#2Dongmei Song (Hebei Medical University)H-Index: 4
Last. Baoshan Wang (Hebei Medical University)H-Index: 4
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It has been previously reported that cisplatin is a well-known anticancer drug being used against a wide range of malignancies including head and neck, ovarian and non-small cell lung carcinoma, and demonstrated its anticancer activity by reacting with DNA or changing cell structure, immune response, reactive oxygen species level (ROS). In this research we proved that cisplatin induced cell injuries and heme oxygenase-1 (HO-1) expression in laryngeal squamous cell cancer Hep-2 cells through ROS ...
11 CitationsSource
#1Dongmei Song (Hebei Medical University)H-Index: 4
#2Geng Song (Hebei Medical University)H-Index: 1
Last. Baoshan Wang (Hebei Medical University)H-Index: 4
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Background and Purpose Ulinastatin (UTI), a serine protease inhibitor, was recently found to have an anti-inflammatory action. However, the mechanisms mediating this anti-inflammatory effect are not well understood. This study tested the hypothesis that UTI suppresses allergic inflammation by inducing the expression of haem oxygenase 1 (HO1). Experimental Approach Control mice and mice sensitized (on days 1, 9 and 14) and challenged (on days 21 to 27) with ovalbumin (OVA) were treated with UTI. ...
4 CitationsSource
#1Baoshan Wang (Hebei Medical University)H-Index: 4
#2Baoyong Yan (Hebei Medical University)H-Index: 2
Last. Shu Fang Liu (The Feinstein Institute for Medical Research)H-Index: 4
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Abstract Objectives Patients with obstructive sleep apnea have an impaired endothelium-dependent vasodilator response. The mechanisms underlying this impairment remain unclear. We tested the hypothesis that chronic intermittent hypoxia (CIH) impairs endothelium-dependent vasodilatation by NF-κB-mediated down-regulation of endothelial nitric oxide synthase (eNOS) expression. Methods Wild type (WT) mice and mice deficient in NF-κB p50 or TNF-α gene were exposed to sham or CIH. Aortic NF-κB activit...
27 CitationsSource
May 1, 2012 in ATS (American Thoracic Society International Conference)
#1Baoshan Wang (Hebei Medical University)H-Index: 4
#2Baoyong Yan (Hebei Medical University)H-Index: 2
Last. Shu F. LiuH-Index: 1
view all 4 authors...
2 CitationsSource
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