Caitlin M. Nass
Johns Hopkins University School of Medicine
Publications 20
#1Richard A. Ferraro (Johns Hopkins University)
#2Caitlin M. Nass (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 9
Last.Sudipa Sarkar (Johns Hopkins University)
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Abstract The treatment of cardiovascular disease in patients with diabetes has seen a sea change in recent years with the development of novel antihyperglycemic agents. The impact of sodium-glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1 RAs), two medication classes introduced in the United States in the wake of increased scrutiny by the US Food and Drug Administration on cardiovascular disease and antihyperglycemic agents, highlight this progressi...
#1Sudipa Sarkar (Johns Hopkins University)
#2Olusola A. Orimoloye (Johns Hopkins University)H-Index: 3
Last.Seth S. Martin (Johns Hopkins University)H-Index: 32
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Current American College of Cardiology/American Heart Association and American Diabetes Association guidelines recommend statin therapy for all patients with diabetes between the ages of 40 and 75, including those without cardiovascular disease (CVD). While diabetes is a major CVD risk factor, not all patients with diabetes have an equal risk of CVD. Thus, a more risk-based approach warrants consideration when recommending statin therapy for the primary prevention of CVD. Coronary artery calcium...
#1Joel B. BraunsteinH-Index: 18
#2Alan ChengH-Index: 3
Last.Roger S. BlumenthalH-Index: 80
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Dyslipidemia is a major risk factor for coronary heart disease (CHD). While some uncertainty exists about the clinical significance of improving high-density lipoprotein cholesterol and triglyceride levels, large primary- and secondary-prevention studies aimed at lowering lowdensity lipoprotein cholesterol levels with statins have convincingly reduced CHD events and total mortality. Despite the strong clinical evidence and widely publicized treatment guidelines, many hyperlipidemic patients rece...
#1Elizabeth A. Martinez (Johns Hopkins University)H-Index: 26
#2Caitlin M. Nass (Johns Hopkins University)H-Index: 9
Last.Lee A. Fleisher (UPenn: University of Pennsylvania)H-Index: 74
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Objective: Several studies suggest that cardiac troponin-I (cTn-I) is a more sensitive indicator of cardiac injury compared with other biochemical markers of injury, but the strategy with the highest diagnostic yield (true positive and true negative) for perioperative surveillance is unknown. The authors undertook a prospective evaluation of the perioperative incidence of myocardial infarction (MI) and evaluated surveillance strategies for the diagnosis of MI. Design: Prospective, cohort study. ...
42 CitationsSource
#1Rita A. Falcone (JHBMC: Johns Hopkins Bayview Medical Center)H-Index: 2
#2Caitlin M. Nass (JHBMC: Johns Hopkins Bayview Medical Center)H-Index: 9
Last.Lee A. Fleisher (JHBMC: Johns Hopkins Bayview Medical Center)H-Index: 74
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Abstract Objective To evaluate the validity of preoperative cardiac stress testing using clinical predictors from the American College of Cardiology/American Heart Association Guidelines on Perioperative Evaluation before Noncardiac Surgery in patients undergoing vascular surgery. Design Prospective, randomized pilot study. Setting Academic medical center. Participants Patients undergoing elective abdominal aortic, infrainguinal, and carotid vascular surgery. Interventions After stratification b...
54 CitationsSource
#1Santhi K. Ganesh (Johns Hopkins University)H-Index: 38
#2Caitlin M. Nass (Johns Hopkins University)H-Index: 9
Last.Roger S. BlumenthalH-Index: 80
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Statins are best-known for their lipid-lowering effects and have been shown to significantly impact the natural progression of coronary atherosclerosis. The mechanism through which they exert this effect is thought to be primarily due to their ability to reduce low-density lipoprotein cholesterol levels. However, there is increasing evidence that statins exert a myriad of other beneficial effects on the vascular wall, thus altering the course of atherosclerotic disease. This article will review ...
16 CitationsSource
Patients undergoing cardiac and high-risk noncardiac surgery have a high incidence of perioperative myocardial infarction. The early diagnosis of perioperative myocardial injury in these patients is complicated. In the perioperative period, there is a high incidence of nonspecific electrocardiographic changes and cardiac biomarker release. It is becoming increasingly imortant to differentiate myocardial necrosis from nonspecific changes because of the need for early intervention and the poential...
3 CitationsSource
#1Alan Cheng (Johns Hopkins University)H-Index: 3
#2Joel B. Braunstein (Johns Hopkins University)H-Index: 18
Last.Roger S. Blumenthal (Johns Hopkins University)H-Index: 80
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Cardiovascular disease (CVD) is the leading cause of death and disability in industrialized societies, due in large part to the lack of a comprehensive approach to control the risk factors for atherosclerosis. One strategy for reducing an individual's global CVD risk relies on a targeted approach that modifies each of the major independent risk factors prevalent in both symptomatic (secondary prevention) and asymptomatic (primary prevention) patients. These interventions include lipid lowering, ...
26 CitationsSource
#1Megan Rist Haymart (Johns Hopkins University)H-Index: 2
#2Timm Dickfeld (Johns Hopkins University)H-Index: 33
Last.Roger S. Blumenthal (Johns Hopkins University)H-Index: 80
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There have been eight major studies assessing percutaneous coronary intervention (PCI) vs. medical therapy in the past 10 years. Women were inadequately represented in many of these studies, but because of similar long-term survival curves in women and men, most of the PCI data can be applied to women until more trials are published. According to currently available data, PCI offers greater angina relief and improvement in exercise tolerance than medicine alone, but has a greater risk of procedu...
2 CitationsSource